Aberration Dmel\Df(2L)VA17

General Information
Symbol	Dmel\Df(2L)VA17	Species	D. melanogaster
Name		FlyBase ID	FBab0001670
Feature type	chromosomal_deletion

Computed Breakpoints include	37C1;37F5
Deleted segment	37C1--37F5
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	ethyl methanesulfonate gamma ray (Gilbert et al., 1984, Wright et al., 1981, Stathakis et al., 1995)
Class of aberration (relative to progenitor)	chromosomal_deletion (Gilbert et al., 1984, Rutledge et al., 1992, Wright et al., 1981, Kania et al., 1995, Stathakis et al., 1995, Whalen and Wilson, 1986)
Breakpoints	37B9-37C1;37F5-38A1 (Kania et al., 1995) 37B9-37C2;37F5-38A1 (Wright et al., 1981, Gilbert et al., 1984, Whalen and Wilson, 1986) 37C1-37C2;37F5 (Rutledge et al., 1992) 37C1-37C2;37F5-38A11 (Stathakis et al., 1995)
Causes alleles	Ddc^VA17 (Black et al., 1987, Wright et al., 1982, Baden et al., 1996)
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 hits Ddc << l(2)37Fd << bk2 << scw
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Hirsh and Davidson, 1981, Gilbert et al., 1984, Rutledge et al., 1992) Ddc DNA coordinates from Gilbert, Hirsh and Wright, 1984, Genetics 106: 679-84: Distal breakpoint within the Ddc gene between +1.4 and 2.4 kb removing the first 5' exon
Comments on Cytology
	Ref: Lindsley and Zimm, 1992 (Kania et al., 1995) Distal breakpoint is within Ddc transcription unit. (Black et al., 1987) Left limit of break 1 from polytene analysis (FBrf0056107) Right limit of break 1 from polytene analysis (FBrf0080145) Left limit of break 2 from polytene analysis (FBrf0035993) Right limit of break 2 from polytene analysis (FBrf0056107)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Aats-asn (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) brat (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, BDGP Project Members, 1994-1999, Stathakis et al., 1995, Wright, 1996) Ddc (Wright et al., 1981, Gilbert et al., 1984, Black et al., 1987, Wright et al., 1982, BDGP Project Members, 1994-1999, Stathakis et al., 1995, Baden et al., 1996, Wright, 1996) l(2)37Cb (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) l(2)37Cc (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, Black et al., 1987, Stathakis et al., 1995, Wright, 1996) l(2)37Cd (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) l(2)37Ce (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) l(2)37Cg (Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) l(2)37Db (BDGP Project Members, 1994-1999) l(2)37Fc (Butler et al., 2001) spi (BDGP Project Members, 1994-1999, Schnepp et al., 1996) suo (Bucciarelli et al., 2003) γTub37C (Stathakis et al., 1995, Wright, 1996)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Acn (Pentz et al., 1986, Wright, 1996, Wright et al., 1981, Stathakis et al., 1995, Gilbert et al., 1984) AcpC (Whalen and Wilson, 1986) amd (Wright et al., 1981, Gilbert et al., 1984, Black et al., 1987, Wright et al., 1982, Stathakis et al., 1995, Wright, 1996) anon-37Ca (Black et al., 1987) Catsup (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, BDGP Project Members, 1994-1999, Stathakis et al., 1995, Wright, 1996) CG10561 (Black et al., 1987, Wright, 1996) cub (Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) fs(2)ltoPP43 (Butler et al., 2001, BDGP Project Members, 1994-1999) hk (Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) l(2)37Bb (Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) l(2)10206 (BDGP Project Members, 1994-1999) l(2)k06712 (BDGP Project Members, 1994-1999, Kania et al., 1995) l(2)k10239 (BDGP Project Members, 1994-1999) Lim3 (Wright et al., 1981, Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) mib2 (Gilbert et al., 1984, Pentz et al., 1986, Stathakis et al., 1995, Wright, 1996) neb (Ohkura et al., 1997) pr (Wright et al., 1981) RpL30 (BDGP Project Members, 1994-1999) Rpn3 (Pentz et al., 1986, Gilbert et al., 1984, Wright, 1996, Stathakis et al., 1995) scw (Butler et al., 2001)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Fails to complement Df(2L)Exel9043. (Bloomington Drosophila Stock Center, 2005.2.3)
NOT in combination with other aberrations
Stocks ( 3 )
Bloomington	3785 Df(2L)VA17, Ddc^VA17 pr¹/CyO
Kyoto	107233 Df(2L)VA17, Ddc^VA17 pr¹/CyO 101373 CyO, Cy¹ dp^lv1 pr¹ cn² / Df(2L)VA17, sna^Sco pr¹
Notes on Origin
Discoverer
	Recovered over Ddc^ts2 in a fly with increased developmental time and with incompletely sclerotinized cuticle. (Wright et al., 1981)
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The Df(2L)VA17 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies. (Mason et al., 2004) "37C1--2;37F5--38A11" was stated as revision. 37C1-37C2 breakpoint is between position +2.8 and +3.5 on the Ddc map relative to the HpaI restriction site near the 3' end of Ddc. (Stathakis et al., 1995) Distal breakpoint of Df(2L)VA17 maps within the Ddc gene. (Wright et al., 1982) "γ ray" was stated as tentative. "ethyl methanesulfonate" was stated as tentative.
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(2L)VA17 (Casso et al., 2008)
Name Synonym
Secondary FlyBase IDs

References ( 26 )

Generate a list of	All references relating to this aberration ( 26 )

List References by type	Research paper ( 22 ) Personal communication to FlyBase ( 2 ) FlyBase analysis ( 1 ) Book ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...