FlyBase Aberration Report: Dmel\Df(2L)VA17

General Information

Symbol

Df(2L)VA17

Species

D. melanogaster

Name

FlyBase ID

FBab0001670

Feature type

chromosomal_deletion

Computed Breakpoints include

37C1;37F5

Features within 37C1--37F5

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

gamma ray

(Stathakis et al., 1995, Gilbert et al., 1984, Wright et al., 1981)

ethyl methanesulfonate

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Kania et al., 1995, Stathakis et al., 1995, Rutledge et al., 1992, Whalen and Wilson, 1986, Gilbert et al., 1984, Wright et al., 1981)

Breakpoints

37B9-37C2;37F5-38A1

(Whalen and Wilson, 1986, Gilbert et al., 1984, Wright et al., 1981)

37C1-37C2;37F5

(Rutledge et al., 1992)

37B9-37C1;37F5-38A1

(Kania et al., 1995)

37C1-37C2;37F5-38A11

(Stathakis et al., 1995)

Causes alleles

Ddc^VA17

(Baden et al., 1996, Black et al., 1987, Wright et al., 1982)

Carries alleles

Transposon Insertions

Formalized genetic data

bk1 hits Ddc << l(2)37Fd << bk2 << scw

Genetic mapping information

Comments

Breakpoint(s) molecularly mapped

(Rutledge et al., 1992, Gilbert et al., 1984, Hirsh and Davidson, 1981)

Ddc DNA coordinates from Gilbert, Hirsh and Wright, 1984, Genetics 106: 679-84: Distal breakpoint within the Ddc gene between +1.4 and 2.4 kb removing the first 5' exon

Comments on Cytology

Ref: Lindsley and Zimm, 1992

(Kania et al., 1995)

Distal breakpoint is within Ddc transcription unit.

(Black et al., 1987)

Left limit of break 1 from polytene analysis (FBrf0056107) Right limit of break 1 from polytene analysis (FBrf0080145) Left limit of break 2 from polytene analysis (FBrf0035993) Right limit of break 2 from polytene analysis (FBrf0056107)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

AsnRS

(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)

brat

(Wright, 1996, Stathakis et al., 1995, BDGP Project Members, 1994-1999, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)

DCTN6-p27

(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)

Ddc

(Baden et al., 1996, Wright, 1996, Stathakis et al., 1995, BDGP Project Members, 1994-1999, Black et al., 1987, Gilbert et al., 1984, Wright et al., 1982, Wright et al., 1981)

l(2)37Cb

(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)

l(2)37Cd

(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)

l(2)37Db

(BDGP Project Members, 1994-1999)

l(2)37Fc

(Butler et al., 2001)

Phb1

(Wright, 1996, Stathakis et al., 1995, Black et al., 1987, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)

Polr1D

(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984)

spi

(Schnepp et al., 1996, BDGP Project Members, 1994-1999)

Top2

(Bucciarelli et al., 2003)

γTub37C

(Wright, 1996, Stathakis et al., 1995)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Acn

(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)

AcpC

(Whalen and Wilson, 1986)

amd

(Wright, 1996, Stathakis et al., 1995, Black et al., 1987, Gilbert et al., 1984, Wright et al., 1982, Wright et al., 1981)

anon-37Ca

(Black et al., 1987)

Catsup

(Wright, 1996, Stathakis et al., 1995, BDGP Project Members, 1994-1999, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)

CG10561

(Wright, 1996, Black et al., 1987)

cub

(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984)

fs(2)ltoPP43

(Butler et al., 2001, BDGP Project Members, 1994-1999)

hook

(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984)

l(2)37Bb

(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984)

l(2)10206

(BDGP Project Members, 1994-1999)

l(2)k06712

(Kania et al., 1995, BDGP Project Members, 1994-1999)

l(2)k10239

(BDGP Project Members, 1994-1999)

Lim3

(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984, Wright et al., 1981)

mib2

(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984)

neb

(Ohkura et al., 1997)

(Wright et al., 1981)

RpL30

(BDGP Project Members, 1994-1999)

Rpn3

(Wright, 1996, Stathakis et al., 1995, Pentz et al., 1986, Gilbert et al., 1984)

scw

(Butler et al., 2001)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

Lethal in combination with Df(2L)Exel6042.

(Kahsai et al., 2016)

Fails to complement Df(2L)Exel9043.

(Bloomington Drosophila Stock Center, 2005.2.3)

NOT in combination with other aberrations

Stocks (3)

Bloomington

3785

Df(2L)VA17, Ddc^VA17 pr¹/CyO

Kyoto

107233

Df(2L)VA17, Ddc^VA17 pr¹/CyO

101373

CyO, Duox^Cy dpy^lv1 pr¹ cn² / Df(2L)VA17, sna^Sco pr¹

Notes on Origin

Discoverer

Recovered over Ddc^ts2 in a fly with increased developmental time and with incompletely sclerotinized cuticle.

(Wright et al., 1981)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

The Df(2L)VA17 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

(Mason et al., 2004)

"37C1--2;37F5--38A11" was stated as revision. 37C1-37C2 breakpoint is between position +2.8 and +3.5 on the Ddc map relative to the HpaI restriction site near the 3' end of Ddc.

(Stathakis et al., 1995)

Distal breakpoint of Df(2L)VA17 maps within the Ddc gene.

(Wright et al., 1982)

"γ ray" was stated as tentative. "ethyl methanesulfonate" was stated as tentative.

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Df(2L)VA17

(Ribot et al., 2022, Kahsai et al., 2016, Casso et al., 2008)

Name Synonyms

Secondary FlyBase IDs

References (28)

Report Sections

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