Aberration Dmel\Df(2L)VA19

General Information
Symbol	Dmel\Df(2L)VA19	Species	D. melanogaster
Name		FlyBase ID	FBab0001672
Feature type	chromosomal_deletion

Computed Breakpoints include	37C2-37C7;38A6-38B1
Deleted segment	37C2--38B1
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	ethyl methanesulfonate (Stathakis et al., 1995) gamma ray (Stathakis et al., 1995)
Class of aberration (relative to progenitor)	chromosomal_deletion (Stathakis et al., 1995, Tavosanis et al., 1997)
Breakpoints	37C2-37D1;38A6-38B1 (Stathakis et al., 1995) 37C2--D1;[] (Tavosanis et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	l(2)37Cg << bk1 << brat << swm << bk2
Genetic mapping information
Comments	Ddc DNA coordinates from Gilbert, Hirsh and Wright, 1984, Genetics 106: 679-84: Distal breakpoint between +30 and +32 kb (E.S. Pentz)
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0084402) Right limit of break 1 from inclusion of γTub37C (FBrf0084402) Limits of break 2 from polytene analysis (FBrf0084402)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	barr (Butler et al., 2001, BDGP Project Members, 1994-1999) brat (Brittnacher and Ganetzky, 1983, BDGP Project Members, 1994-1999, Stathakis et al., 1995, Wright, 1996) fs(2)ltoPP43 (Butler et al., 2001) l(2)37Db (Brittnacher and Ganetzky, 1983, BDGP Project Members, 1994-1999) l(2)37Dc (Brittnacher and Ganetzky, 1983) l(2)37De (Brittnacher and Ganetzky, 1983) l(2)37Di (Brittnacher and Ganetzky, 1983) l(2)37Fe (Butler et al., 2001) l(2)38Ab (Butler et al., 2001) l(2)k09314b (BDGP Project Members, 1994-1999) neb (Butler et al., 2001, BDGP Project Members, 1994-1999) pr (Butler et al., 2001) spi (BDGP Project Members, 1994-1999) swm (Brittnacher and Ganetzky, 1983) γTub37C (Stathakis et al., 1995, Wright, 1996, Tavosanis et al., 1997)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Aats-asn (Stathakis et al., 1995, Wright, 1996) Acn (Stathakis et al., 1995, Wright, 1996) amd (Stathakis et al., 1995, Wright, 1996) cad (Butler et al., 2001) Catsup (Stathakis et al., 1995, Wright, 1996) cub (Stathakis et al., 1995, Wright, 1996) Ddc (BDGP Project Members, 1994-1999, Stathakis et al., 1995, Wright, 1996) Fs(2)Ket (Butler et al., 2001) hk (Stathakis et al., 1995, Wright, 1996) l(2)37Bb (Stathakis et al., 1995, Wright, 1996) l(2)37Cb (Stathakis et al., 1995, Wright, 1996) l(2)37Cc (Stathakis et al., 1995, Wright, 1996) l(2)37Cd (Stathakis et al., 1995, Wright, 1996) l(2)37Ce (Stathakis et al., 1995, Wright, 1996) l(2)37Cg (Stathakis et al., 1995, Wright, 1996) l(2)38Db (Butler et al., 2001) l(2)38EFd (Butler et al., 2001, BDGP Project Members, 1994-1999) Lim3 (Stathakis et al., 1995, Wright, 1996) mib2 (Stathakis et al., 1995, Wright, 1996) RpL30 (BDGP Project Members, 1994-1999) Rpn3 (Stathakis et al., 1995, Wright, 1996) spir (Butler et al., 2001)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Stocks ( 0 )

Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	37C2-37D1 breakpoint is between position +30.8 and +31.8 on the Ddc map relative to the HpaI restriction site near the 3' end of Ddc. (Stathakis et al., 1995) "γ ray" was stated as tentative. "ethyl methanesulfonate" was stated as tentative.
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(2L)VA19
Name Synonym
Secondary FlyBase IDs

References ( 10 )
Research paper	De Luca et al., 2003, Nat. Genet. 34(4): 429--433 Dopa decarboxylase (Ddc) affects variation in Drosophila longevity. [FBrf0162261] Butler et al., 2001, Genetics 158(4): 1597--1614 Map position and expression of the genes in the 38 region of Drosophila. [FBrf0138405] Tavosanis et al., 1997, EMBO J. 16(8): 1809--1819 Essential role for -tubulin in the acentriolar female meiotic spindle of Drosophila. [FBrf0093749] Krueger et al., 1996, Cell 84(4): 611--622 The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila. [FBrf0086508] Wright, 1996, J. Hered. 87(3): 175--190 The Wilhelmine E. Key 1992 Invitational lecture. Phenotypic analysis of the Dopa decarboxylase gene cluster mutants in Drosophila melanogaster. [FBrf0089206] Stathakis et al., 1995, Genetics 141(2): 629--655 The genetic and molecular organization of the Dopa decarboxylase gene cluster of Drosophila melanogaster. [FBrf0084402] Brittnacher and Ganetzky, 1983, Genetics 103: 659--673 On the components of Segregation Distortion in Drosophila melanogaster. [FBrf0039473]
Personal communication to FlyBase	BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]