Aberration Dmel\Df(2L)b84a2

General Information
Symbol	Dmel\Df(2L)b84a2	Species	D. melanogaster
Name	Deficiency (2L) black	FlyBase ID	FBab0001730
Feature type	chromosomal_deletion

Computed Breakpoints include	34C3;35B1
Deleted segment	34C3--35B1
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	gamma ray
Class of aberration (relative to progenitor)	chromosomal_deletion (Gubb et al., 1990, Roote et al., 1996, Tinker et al., 1998)
Breakpoints	34C3;35A4 (Gubb et al., 1990, Roote et al., 1996) 34C3;35B1 (Tinker et al., 1998)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << kuz << elA << bk2 << noc
Genetic mapping information
Comments
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0051930) Limits of break 2 from polytene analysis (FBrf0103384)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	crle (Davis et al., 1997) elA (Davis et al., 1990, Roote et al., 1996, Davis et al., 1997) elB (Davis et al., 1990, Roote et al., 1996, Davis et al., 1997) kuz (Roote et al., 1996) l(2)34Fc (Roote et al., 1996) l(2)34Fd (Davis et al., 1990, Roote et al., 1996) ms(2)34Fe (Davis et al., 1990, Roote et al., 1996) pburs (Davis et al., 1990, Roote et al., 1996, Davis et al., 1997) Pgant35A (Davis et al., 1990, Roote et al., 1996)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Adh (Roote, 2002.1.15, Roote et al., 1996) mol (Roote et al., 1996) noc (Davis et al., 1990, Cheah et al., 1994, Roote et al., 1996, Davis et al., 1997) osp (Roote et al., 1996) vas (Tinker et al., 1998)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Ts(Y;2Lt)GT2+Ts(YSt;2Rt)A80/Df(2L)b84a2 and Ts(Y;2Lt)a15+Ts(YSt;2Rt)A80/Df(2L)b84a2 animals usually die as pharate adults, escapers have crippled legs. Df(2L)A400/Df(2L)b84a2, Df(2L)el14/Df(2L)b84a2 and Ts(Y;2Lt)el⁴+Ts(YSt;2Rt)R15/Df(2L)b84a2 animals die as pharate adults with crippled legs. Df(2L)TE35B-12/Df(2L)b84a2, Df(2L)TE35BC-8/Df(2L)b84a2 and Df(2L)TE35B-1/Df(2L)b84a2 animals have an early lethal phenotype. Df(2L)el16/Df(2L)b84a2 and Df(2L)fn2/Df(2L)b84a2 animals usually die as pharate adults, rare escapers have crippled legs and show an "elbow" phenotype. Df(2L)el28/Df(2L)b84a2 animals often do not survive to adulthood, those that do have have an "elbow" phenotype. Df(2L)TE35B-6/Df(2L)b84a2 animals often do not survive to adulthood, those that do have an "elbow" phenotype. (Davis et al., 1997) Does not suppress the zeste phenotype in a z¹ w^11E4; Tp(1;2)TE35B homologue. (Gubb et al., 1990)
NOT in combination with other aberrations	Chromosome has no effect on the physical interaction between tandemly duplicated copies of w⁺ and z¹, despite having breakpoints within the critical region. (Gubb et al., 1990)
Stocks ( 0 )

Notes on Origin
Discoverer	G. Harrington.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	Reported to not delete Adhr in error; see FBrf0141768 for correction. (Roote et al., 1996)
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Df(2L)b84a2
Name Synonym	Deficiency (2L) black
Secondary FlyBase IDs

References ( 10 )
Research paper	Tinker et al., 1998, Dev. Biol. 199(1): 1--10 Requirement for the vasa RNA helicase in gurken mRNA localization. [FBrf0103384] Davis et al., 1997, Hereditas 126(1): 67--75 Genetic and phenotypic analysis of the genes of the elbow-no-ocelli region of chromosome 2L of Drosophila melanogaster. [FBrf0093413] Roote et al., 1996, D. I. S. 77: 55--65 Aberrations in the l(2)34Fc - l(2)35Bb region of chromosome arm 2L. [FBrf0091422] Cheah et al., 1994, Mol. Cell. Biol. 14(2): 1487--1499 The Drosophila l(2)35Ba/nocA gene encodes a putative Zn finger protein involved in the development of the embryonic brain and the adult ocellar structures. [FBrf0066938] Davis et al., 1990, Genetics 126: 105--119 The molecular analysis of the el-noc complex of Drosophila melanogaster. [FBrf0051916] Gubb et al., 1990, Genetics 126: 167--176 A novel transvection phenomenon affecting the white gene of Drosophila melanogaster. [FBrf0051930] Chia et al., 1985, J. Mol. Biol. 186(2): 689--706 Molecular analysis of the Adh region of the genome of Drosophila melanogaster. [FBrf0043115]
Personal communication to FlyBase	Roote, 2002.1.15, Adhr status unknown. Adhr status unknown. [FBrf0141768]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]