Aberration Dmel\Df(2L)b85b2

General Information
Symbol	Dmel\Df(2L)b85b2	Species	D. melanogaster
Name	Deficiency (2L) black	FlyBase ID	FBab0001742
Feature type	chromosomal_deletion
Also Known As	b^85b2

Computed Breakpoints include	34D4;34D8
Deleted segment	34D4--34D8
Map ( GBrowse )	Untitled Document Error No matching regions found.
Sequence coordinates	2L:13,817,515..13,820,404 [+] (Df(2L)b85b2:bk1) (Simon et al., 1991)
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	gamma ray (Alexandrova et al., 1996, Alexandrov and Alexandrova, 1991, Roote, 1995.3.27, Alexandrov and Alexandrova, 1986) irradiation (The Moscow Regional Drosophila melanogaster Stock Center, Dubna) spontaneous (The Moscow Regional Drosophila melanogaster Stock Center, Dubna)
Class of aberration (relative to progenitor)	chromosomal_deletion (Alexandrova et al., 1996, Alexandrov and Alexandrova, 1991, Alexandrov and Alexandrova, 1986)
Breakpoints	34D2-34D4;34D8-34E2 (Alexandrov and Alexandrova, 1986) 34D2;34D8 (Alexandrov and Alexandrova, 1991) 34D4;34D5 (Alexandrova et al., 1996) [];[] (Roote, 1995.3.27)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	Sos << bk1 << b << tam << bk2 << Sop2
Genetic mapping information
Comments
Comments on Cytology
	Stated to be a cytologically invisible deletion. (Roote, 1995.3.27) Left limit of break 1 from polytene analysis (FBrf0092446) Right limit of break 1 from polytene analysis (FBrf0044054) Left limit of break 2 from inclusion of tam (FBrf0077941) Right limit of break 2 from polytene analysis (FBrf0053558)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	b (Iyengar et al., 1999, Roote, 2000.7.3, Alexandrov and Alexandrova, 1991, Roote, 1995.3.27, Alexandrova et al., 1996) tam (Iyengar et al., 1999, Roote, 2000.7.3, Roote, 1995.3.27, Alexandrova et al., 1996, Roote, 1997.6.3)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Arpc1 (Roote, 2000.7.3, Roote, 1997.6.3) Orc5 (Roote, 1997.6.3) Sos (Roote, 2000.7.3)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Homozygous lethal. (Alexandrov and Alexandrova, 1986)
Stocks ( 0 )

Notes on Origin
Discoverer	Alexandrov. (Roote, 1995.3.27)
	Induced in: a mature sperm. (Alexandrov and Alexandrova, 1986)
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	"irradiation" was stated as tentative. "spontaneous" was stated as tentative. (The Moscow Regional Drosophila melanogaster Stock Center, Dubna)
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	b85b2 (Alexandrova et al., 1996) b^85b2 (Alexandrov and Alexandrova, 1986, The Moscow Regional Drosophila melanogaster Stock Center, Dubna) Df(2L)85b2 (Alexandrov and Alexandrova, 1991) Df(2L)b85b2
Name Synonym	Deficiency (2L) black
Secondary FlyBase IDs

References ( 14 )
Research paper	Iyengar et al., 1999, Genetics 153(4): 1809--1824 The tamas gene, identified as a mutation that disrupts larval behavior in Drosophila melanogaster, codes for the mitochondrial DNA polymerase catalytic subunit (DNApol-125). [FBrf0123061] Alexandrova et al., 1996, Radiat. biol., radioecol., Moskva 36(6): 805--814 [Radiation cytogenetics of multilocus deletions and the principles of the superchromomeric organization of eukaryotic euchromatin.] [FBrf0092446] Bonfini et al., 1992, Science 255: 603--606 The Son of sevenless gene product: a putative activator of Ras. [FBrf0057637] Alexandrov and Alexandrova, 1991, D. I. S. 70: 16 and 19 The genetic and cytogenetic boundaries of the radiation-induced chromosome rearrangements scored as lethal black mutations in D. melanogaster. [FBrf0053558] Simon et al., 1991, Cell 67(23): 701--716 Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase. [FBrf0053392] Alexandrov and Alexandrova, 1986, D. I. S. 63: 159--161 Report of new mutants. [FBrf0044054] Alexandrova, 1986, D. I. S. 63: 21--22 Genetic and cytogenetic mapping of the chromosome rearrangement breakpoints induced by high- and low-LET radiations around the black locus of Drosophila melanogaster. [FBrf0044068] Alexandrov, 1984, D. I. S. 60: 45--47 Comparative genetics of neutron- and -ray-induced lethal b, cn and vg mutations in D. melanogaster. [FBrf0040665]
Personal communication to FlyBase	Roote, 2000.7.3, The first 100 Dfs in the 34-36 region - updates. The first 100 Dfs in the 34-36 region - updates. [FBrf0129267] Roote, 1997.6.3, Formalized genetic data for deletions. Formalized genetic data for deletions. [FBrf0093853] Roote, 1995.3.27, Help FlyBase - Roote 2. Help FlyBase - Roote 2. [FBrf0077941]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Stock list	The Moscow Regional Drosophila melanogaster Stock Center, Dubna, Russia, 1997, D. I. S. 80: 109--130 Stock list. [FBrf0098381]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]

Aberration Dmel\Df(2L)b85b2

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