Limits of break 1 from polytene analysis (FBrf0053558) Left limit of break 2 from inclusion of vas (FBrf0077941) Right limit of break 2 from polytene analysis (FBrf0080145)
Df(2L)b87e25 in combination with a pair of introgressions from D.simulans spanning 30F1-31E7 to 35D7-36A14 Dsim\Int(2L)S and 21A1 to 22D1--23A2 Dsim\Int(2L)D produces semi-sterile male flies. These flies are female sterile.
The Df(2L)b87e25 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the suppressor maps to the tip of 2L rather than to the site of the deficiency. In addition, the deficiency chromosome fails to complement lethal mutations of l(2)gl.