FB2021_05, released October 15, 2021

Aberration: Dmel\Df(2L)b87e25

Open Close
General Information
Symbol
Df(2L)b87e25
Species
D. melanogaster
Name
Deficiency (2L) black
FlyBase ID
FBab0001747
Feature type
chromosomal_deletion
Computed Breakpoints include

34C1;35C1

Features within 34C1--35C1
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
gamma ray
(Alexandrova et al., 1996, Roote, 1995.3.27, Alexandrov and Alexandrova, 1991)
irradiation
(The Moscow Regional Drosophila melanogaster Stock Center, Dubna)
spontaneous
(The Moscow Regional Drosophila melanogaster Stock Center, Dubna)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Tinker et al., 1998, The Moscow Regional Drosophila melanogaster Stock Center, Dubna, Alexandrova et al., 1996, Harbecke and Lengyel, 1995, Kania et al., 1995, Roote, 1995.3.27, Alexandrov and Alexandrova, 1991)
Breakpoints

34C1;35C1-35C2

(Roote, 1995.3.27, Alexandrov and Alexandrova, 1991)

34B12-34C1;35B10-35C1

(Harbecke and Lengyel, 1995, Kania et al., 1995)

34D3;35B10

(Alexandrova et al., 1996)

34C1;35B10

(The Moscow Regional Drosophila melanogaster Stock Center, Dubna)

34C1-34C2;35B10-35C1

(Tinker et al., 1998)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << kuz << vas << bk2 << stc

Genetic mapping information
Comments

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

(Marygold et al., 2007)
Comments on Cytology

Ref: Lindsley and Zimm, 1992

(Kania et al., 1995)

Limits of break 1 from polytene analysis (FBrf0053558) Left limit of break 2 from inclusion of vas (FBrf0077941) Right limit of break 2 from polytene analysis (FBrf0080145)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Inferred to overlap with: Df(2L)BSC345.

    (Christensen et al., 2007.10.29)
    NOT in combination with other aberrations

    Flies heterozygous for the deletion do not show a Minute bristle phenotype.

    (Marygold et al., 2007)

    Lethal in combination with: Df(2L)BSC147. Inferred to overlap with: Df(2L)BSC147.

    (Christensen and Cook, 2006.3.8)

    Df(2L)b87e25 in combination with a pair of introgressions from D.simulans spanning 30F1-31E7 to 35D7-36A14 Dsim\Int(2L)S and 21A1 to 22D1--23A2 Dsim\Int(2L)D produces semi-sterile male flies. These flies are female sterile.

    (Sawamura et al., 2000)

    Suppresses the ommatidial polarity phenotype of dshhs.sev.B. Suppresses the ommatidial polarity phenotype of msnEP549 when driven by Scer\GAL4hs.2sev.

    (Paricio et al., 1999)

    No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

    (Halsell and Kiehart, 1998)

    Shows no maternal enhancement of dpphr4.

    (Nicholls and Gelbart, 1998)

    Deficient embryos show an uninterpretable mutant midgut phenotype.

    (Bilder and Scott, 1995)

    Homozygous embryos are very abnormal compared to wild-type.

    (Harbecke and Lengyel, 1995)
    Stocks (3)
    Notes on Origin
    Discoverer
     

    The stock contains a second-site deletion uncovering l(2)gl.

    (Roegiers et al., 2009)
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2L)b87e25 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the suppressor maps to the tip of 2L rather than to the site of the deficiency. In addition, the deficiency chromosome fails to complement lethal mutations of l(2)gl.

    (Mason et al., 2004)

    "irradiation" was stated as tentative. "spontaneous" was stated as tentative.

    (The Moscow Regional Drosophila melanogaster Stock Center, Dubna)
    Synonyms and Secondary IDs (11)
    References (43)