A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Aberration Dmel\Df(2L)b87e25

General Information
SymbolDmel\Df(2L)b87e25SpeciesD. melanogaster
NameDeficiency (2L) blackFlyBase IDFBab0001747
Feature typechromosomal_deletionCreated / Updated2006-08-22/2006-08-22
Formalized genetic data bk1 << kuz << vas << bk2 << stc
Sequence coordinates
Deleted segment34C1--35C1
Duplicated segment
Computed Breakpoints include 34C1;35C1
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)
Breakpoints
34C1-34C2;35B10-35C1
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
hide Comments on Cytology
Limits of break 1 from polytene analysis (FBrf0053558) Left limit of break 2 from inclusion of vas (FBrf0077941) Right limit of break 2 from polytene analysis (FBrf0080145)
 
Ref: Lindsley and Zimm, 1992
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Df(2L)b87e25 in combination with a pair of introgressions from D.simulans spanning 30F1-31E7 to 35D7-36A14 Dsim\Int(2L)S and 21A1 to 22D1--23A2 Dsim\Int(2L)D produces semi-sterile male flies. These flies are female sterile.
Deficient embryos show an uninterpretable mutant midgut phenotype.
Homozygous embryos are very abnormal compared to wild-type.
Lethal in combination with: Df(2L)BSC147. Inferred to overlap with: Df(2L)BSC147.
No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.
Shows no maternal enhancement of dpphr4.
Suppresses the ommatidial polarity phenotype of dshhs.sev.B. Suppresses the ommatidial polarity phenotype of msnEP549 when driven by Scer\GAL4hs.2sev.
hide Position Effect Variegation Data
  
hide Stocks ( 3 )
Bloomington
Kyoto
hide Notes on Origin
Discoverer
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
      hide Other Comments
      "irradiation" was stated as tentative. "spontaneous" was stated as tentative.
      The Df(2L)b87e25 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the suppressor maps to the tip of 2L rather than to the site of the deficiency. In addition, the deficiency chromosome fails to complement lethal mutations of l(2)gl.
      hide Synonyms & Secondary IDs ( 9 )
      Reported As
      Symbol Synonym
      Df(2L)b80e25
      Df(2L)b87E25
       
      Df(2L)b87e35
      Name Synonym
      Deficiency (2L) black
       
      Secondary FlyBase IDs
        hide References ( 34 )
        Generate a list of
        List References by type
        hide Recent research papers ( 1 )
        Crest et al., 2007, Genetics 175(2): 567--584
        Onset of the DNA replication checkpoint in the early Drosophila embryo. [FBrf0194644]