Aberration Dmel\Df(2L)cl7

General Information
Symbol	Dmel\Df(2L)cl7	Species	D. melanogaster
Name	Deficiency (2L) clot	FlyBase ID	FBab0001762
Feature type	chromosomal_deletion
Also Known As	Df(2L)clot-7, Df(2L)clot7, Df(2L)cl-7, Df(2L)cl⁷

Computed Breakpoints include	25D7;26A7
Deleted segment	25D7--26A7
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray (Kotarski et al., 1983, Knipple and MacIntyre, 1984, Ashburner et al., 1980)
Class of aberration (relative to progenitor)	chromosomal_deletion (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Schupbach and Wieschaus, 1991, Pauli et al., 1995, de Belle et al., 1989, Knipple and MacIntyre, 1984, Landecker et al., 1994, George and Terracol, 1997, Ashburner et al., 1980, Giansanti et al., 1998, Locke et al., 1988)
Breakpoints	25D5-25D6;26A7 (Landecker et al., 1994, Giansanti et al., 1998) 25D5-25D6;26A7-26A8 (Szidonya and Reuter, 1988, George and Terracol, 1997) 25D5-25D7;26A7-26A8 (Szidonya and Reuter, 1988) 25D7-25E1;26A7-26A8 (Kotarski et al., 1983, Schupbach and Wieschaus, 1989, Schupbach and Wieschaus, 1991, Pauli et al., 1995) 25D7;26A7 (Ashburner et al., 1980) 25D7;26A7-26A8 (Locke et al., 1988) 25E1-25E2;26A7 (Knipple and MacIntyre, 1984) 25E1-25E2;26A7-26A8 (de Belle et al., 1989)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	cype << bk1 << nompC << l(2)26Aa << bk2 << eIF-4a
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Knipple et al., 1991)
Comments on Cytology
	All limits from polytene analysis (FBrf0034393)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	bchs (Finley et al., 2003) cl (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Davis and MacIntyre, 1988, Knipple et al., 1991) dsf (Finley et al., 1997) E(var)25F (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) E(var)26A (Locke et al., 1988) Gpdh (Kotarski et al., 1983, Davis and MacIntyre, 1988, Knipple et al., 1991, Wojtas et al., 1997) Hel25E (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) ifc (Kotarski et al., 1983) l(2)25Ea (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Ed (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Ee (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Ef (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Eg (Kotarski et al., 1983) l(2)25Fa (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Fb (Kotarski et al., 1983) l(2)25Fc (Kotarski et al., 1983) l(2)25Fd (Kotarski et al., 1983) l(2)25Fe (Kotarski et al., 1983) l(2)PN-6 (Racine et al., 1980) l(2)PN-11 (Racine et al., 1980) Lam (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, BDGP Project Members, 1994-1999) mid (Szidonya and Reuter, 1988, Kotarski et al., 1983, Tearle and Nusslein-Volhard, 1987, Szidonya and Reuter, 1988) nompC (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, George and Terracol, 1997) Vm26Aa (Schupbach and Wieschaus, 1991) Vm26Ab (Savant and Waring, 1989)
Molecular Data
Completely deleted	dsf (Finley et al., 2003)
Genes NOT Deleted / Disrupted
Complementation Data
	chic (Giansanti et al., 1998, Wills et al., 1999) cype (BDGP Project Members, 1994-1999) dp (Kotarski et al., 1983) eIF-4a (Kotarski et al., 1983, Dorn et al., 1993) for (de Belle et al., 1989) fusl (Long et al., 2008) Gal (Knipple and MacIntyre, 1984) l(2)25Ca (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Cc (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Cd (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Ce (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Cf (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Cg (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)26Ad (Kotarski et al., 1983) l(2)26Ae (Kotarski et al., 1983) l(2)26Cf (Kotarski et al., 1983) l(2)04884 (BDGP Project Members, 1994-1999) Msp-300 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) RpL37A (Szidonya and Reuter, 1988, Kotarski et al., 1983, Szidonya and Reuter, 1988) tkv (Kotarski et al., 1983, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) vri (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, George and Terracol, 1997) wg (Kotarski et al., 1983)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Df(2L)cl7 causes reduced lifespan in combination with either Df(2L)dsf3 or Df(2L)dsf4. (Finley et al., 2003) Effect on variegation of y in In(1)y^3P and Sb in T(2;3)Sb^V studied: inactivation of y occurs independently of inactivation of Sb. (Bishop, 1992) Enhances position effect variegation at the w locus caused by In(1)w^m4, C(1;YL)w^mMc or T(1;4)w^m5 and position effect variegation at the y locus caused by In(1)y^3P. (Locke et al., 1988) Lethal in combination with Df(2L)Gpdh78 (some survivors are seen). Lethal in combination with Df(2L)Gpdh75. Lethal in combination with Df(2L)cl1. Lethal in combination with Df(2L)cl2. Lethal in combination with Df(2L)GpdhA. Viable in combination with T(Y;2)H151. Viable in combination with T(Y;2)D222. (Racine et al., 1980)
NOT in combination with other aberrations	The lifespan of Df(2L)cl7/+ flies is not significantly different to wild type. (Finley et al., 2003) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) Enhance mottling in w^m4. (Tartof et al., 1989) Suppresses In(1)w^m4h position-effect variegation. (Szidonya and Reuter, 1988)
Stocks ( 3 )
Bloomington	3365 Df(2L)cl7, pr¹ cn¹/CyO
Kyoto	107009 Df(2L)cl7, pr¹ cn¹/CyO 101369 CyO, Cy¹ dp^lv1 pr¹ cn² / Df(2L)cl7, Adh^nC1 cn¹ bw¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The presence of a variegating chromosome and a modifier chromosome in the same parental genome can alter the amount the amount of variegation formed in the progeny. The genomic imprinting is not determined by the parental origin of the variegating chromosome but is instead determined by the genetic background the variegating chromosome is subjected to during gametogenesis. (Bishop and Jackson, 1996)
Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym	Df(2L)c17 (Landecker et al., 1994) Df(2L)cl-7 (Racine et al., 1980, Tearle and Nusslein-Volhard, 1987, Wojtas et al., 1997, Kotarski et al., 1983) Df(2L)cl7 (Khodosh et al., 2006, Long et al., 2008, Casso et al., 2008, Popkova et al., 2012) Df(2L)cl.7 (Ashburner et al., 1980) Df(2L)cl⁷ (Wills et al., 1999, George and Terracol, 1997, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Df(2L)clot7 (Finley et al., 2003, Giansanti et al., 1998, Simonsen et al., 2007, Kriston-Vizi et al., 2011) Df(2L)clot-7 (Bishop and Jackson, 1996, Knipple and MacIntyre, 1984, Davis and MacIntyre, 1988, Dorn et al., 1993, Knipple et al., 1991, Sullivan et al., 2003)
Name Synonym	Deficiency (2L) clot
Secondary FlyBase IDs

References ( 40 )

Generate a list of	All references relating to this aberration ( 40 )

List References by type	Research paper ( 36 ) Personal communication to FlyBase ( 1 ) FlyBase analysis ( 1 ) Stock list ( 1 ) Book ( 1 )
Recent research papers ( 2 )
	Popkova et al., 2012, PLoS Genet. 8(12): e1003159 Polycomb controls gliogenesis by regulating the transient expression of the gcm/glide fate determinant. [FBrf0220515] Kriston-Vizi et al., 2011, BMC Bioinformatics 12: 232 Gebiss: an ImageJ plugin for the specification of ground truth and the performance evaluation of 3d segmentation algorithms. [FBrf0214312] Show all research papers ...