Aberration Dmel\Df(2L)dp-h28

General Information
Symbol	Dmel\Df(2L)dp-h28	Species	D. melanogaster
Name	Deficiency (2L) dumpy	FlyBase ID	FBab0001772
Feature type	chromosomal_deletion
Also Known As	Df(2L)dp^h28

Computed Breakpoints include	24D8;25A1
Deleted segment	24D8--25A1
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_deletion (Semeshin and Szidonya, 1985, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Bryant et al., 1988, Pauli et al., 1995)
Breakpoints	24D7-24D8;24F7-25A1 (Szidonya and Reuter, 1988, Bryant et al., 1988, Szidonya and Reuter, 1988) 24D8;24F6-24F7 (Semeshin and Szidonya, 1985, Pauli et al., 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	l(2)24De << bk1 << tutl << dp << bk2 << slf
Genetic mapping information
Comments
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0042240) Left limit of break 2 from inclusion of dp (FBrf0047784) Right limit of break 2 from polytene analysis (FBrf0047784)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	dp (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Mathew et al., 2009) dw-24E (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)24Fa (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)24Fc (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Psf2 (Mathew et al., 2009) RpL27A (Bryant et al., 1988, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Mathew et al., 2009) Su(var)2-8 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Tps1 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Mathew et al., 2009) tutl (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Mathew et al., 2009)
Molecular Data
Completely deleted	Atet (Mathew et al., 2009) CG3652 (Mathew et al., 2009) CG12677 (Mathew et al., 2009) CG15429 (Mathew et al., 2009) CG15436 (Mathew et al., 2009) CG15631 (Mathew et al., 2009) Tps1 (Mathew et al., 2009) Traf4 (Mathew et al., 2009)
Genes NOT Deleted / Disrupted
Complementation Data
	bcn92 (Mathew et al., 2009) CG11927 (Mathew et al., 2009) cl (Bryant et al., 1988) dp (Bryant et al., 1988) ed (Szidonya and Reuter, 1988, Bryant et al., 1988, Szidonya and Reuter, 1988) ft (Szidonya and Reuter, 1988, Bryant et al., 1988, Szidonya and Reuter, 1988, Mathew et al., 2009) l(2)24Dc (Szidonya and Reuter, 1988, Bryant et al., 1988, Szidonya and Reuter, 1988) l(2)24Dd (Szidonya and Reuter, 1988, Bryant et al., 1988, Szidonya and Reuter, 1988) l(2)24De (Szidonya and Reuter, 1988, Bryant et al., 1988, Szidonya and Reuter, 1988) l(2)25Ab (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Ba (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Bb (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Bc (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Bd (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Be (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Bf (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Bg (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Ca (Bryant et al., 1988) M(2)24D (Szidonya and Reuter, 1988, Bryant et al., 1988, Szidonya and Reuter, 1988) mRpS2 (Mathew et al., 2009) RpL37A (Bryant et al., 1988) slf (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) tkv (Bryant et al., 1988)
Molecular Data
	CG3225 (Mathew et al., 2009) CG11929 (Mathew et al., 2009) CG15634 (Mathew et al., 2009) dp (Mathew et al., 2009)
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Approximately a quarter of embryos from Df(2L)dp-h28 heterozygotes exhibit a delay in the invagination of the ventral furrow as compared to controls. (Mathew et al., 2009) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) olv class of dp phenotype. Reduced viability and fertility. (Szidonya and Reuter, 1988)
Stocks ( 0 )

Notes on Origin
Discoverer
	Isolated over Dp(2;2)B3 = Dp(2;2)23E2-3;26E2-F1
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df(2L)dp^h28 (Bryant et al., 1988, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Semeshin and Szidonya, 1985) Df(2L)dp-h28 (Mathew et al., 2009)
Name Synonym	Deficiency (2L) dumpy
Secondary FlyBase IDs

References ( 9 )
Research paper	Mathew et al., 2009, PLoS ONE 4(10): e7437 A small genomic region containing several loci required for gastrulation in Drosophila. [FBrf0208913] Pauli et al., 1995, Genetics 139(2): 713--732 Identification of regions interacting with ovo^D mutations: Potential new genes involved in germline sex determination or differentiation in Drosophila melanogaster. [FBrf0080317] Pauli et al., 1995, D. I. S. 76: 107--124 Dose dependent enhancers and suppressors of ovoD2. [FBrf0082455] Bryant et al., 1988, Dev. Biol. 129: 541--554 Mutations at the fat locus interfere with cell proliferation control and epithelial morphogenesis in Drosophila. [FBrf0047838] Szidonya and Reuter, 1988, Genet. Res. (Camb.) 51(3): 197--208 Cytogenetic analysis of the echinoid (ed), dumpy (dp) and clot (cl) region in Drosophila melanogaster. [FBrf0048137] Szidonya and Reuter, 1988, D. I. S. 67: 77--79 Cytogenetics of the 24D4-25F2 region of the Drosophila melanogaster 2L chromosome. [FBrf0047784] Semeshin and Szidonya, 1985, D. I. S. 61: 148--154 EM mapping of rearrangements in the 24-25 sections of Drosophila melanogaster 2L chromosomes. [FBrf0042240]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]