Aberration Dmel\Df(2L)dpp^d14

General Information
Symbol	Dmel\Df(2L)dpp^d14	Species	D. melanogaster
Name	Deficiency (2L) decapentaplegic	FlyBase ID	FBab0001786
Feature type	chromosomal_deletion
Also Known As	Df(2L)dpp¹⁴

Computed Breakpoints include	22F1-22F2;23A2
Deleted segment	22F1--23A2
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_deletion (Hartenstein et al., 1997, Segal and Gelbart, 1985)
Breakpoints	22E4-22F2;22F3-23A1 (Segal and Gelbart, 1985) 22E4-22F2;23A2 (Hartenstein et al., 1997)
Causes alleles	dpp^d14 (Cho et al., 2000, Spencer et al., 1982, Segal and Gelbart, 1985, Posakony et al., 1990, Diaz-Benjumea et al., 1994, Lecuit et al., 1996, Johnson et al., 2007)
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 hits dpp << Drp1 << bk2 << colt
Genetic mapping information
Comments
Comments on Cytology
	Ref: Spencer et al., 1982, Cell 28(3): 451--461. (Littleton and Bellen, 1994) Left limit of break 1 from non-inclusion of dpp (citation unavailable) Right limit of break 1 from inclusion of dpp (FBrf0037609) Limits of break 2 from polytene analysis (FBrf0099765)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	dpp (Spencer et al., 1982, Segal and Gelbart, 1985, BDGP Project Members, 1994-1999) Drp1 (Ly, 2005.3.2, Bergstrom et al., 1995) oaf (Spencer et al., 1982, Bergstrom et al., 1995)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	colt (Hartenstein et al., 1997) l(2)00231 (BDGP Project Members, 1994-1999) l(2)02321 (BDGP Project Members, 1994-1999) l(2)03728 (BDGP Project Members, 1994-1999) l(2)09639 (BDGP Project Members, 1994-1999)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Df(2L)OK371Δ complements Df(2L)dpp^d14. (Mahr and Aberle, 2006)
NOT in combination with other aberrations	The Df(2L)dpp^d14 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004)
Stocks ( 2 )
Bloomington	6648 Df(2L)dpp^d14/In(2LR)Gla, wg^Gla-1
Kyoto	130323 Df(2L)dpp^d14/In(2LR)Gla, wg^Gla-1
Notes on Origin
Discoverer	Spencer.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	Df(2L)dpp14 (Mahr and Aberle, 2006) Df(2L)dpp¹⁴ (Spencer et al., 1982, Littleton and Bellen, 1994) Df(2L)dpp^d1 (Royet and Finkelstein, 1997) Df(2L)dpp^d14 (Johnson et al., 2007) Df(2L)dpp-d14 (Mason et al., 2004)
Name Synonym	Deficiency (2L) decapentaplegic
Secondary FlyBase IDs

References ( 18 )
Research paper	Johnson et al., 2007, Genetics 176(3): 1609--1624 Defective decapentaplegic signaling results in heart overgrowth and reduced cardiac output in Drosophila. [FBrf0201166] Mahr and Aberle, 2006, Gene Expr. Patterns 6(3): 299--309 The expression pattern of the Drosophila vesicular glutamate transporter: a marker protein for motoneurons and glutamatergic centers in the brain. [FBrf0190508] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Cho et al., 2000, Cell 103(2): 331--342 Novel signaling from the Peripodial Membrane is essential for Eye Disc patterning in Drosophila. [FBrf0131275] Hartenstein et al., 1997, Genetics 147(4): 1755--1768 The congested-like tracheae gene of Drosophila melanogaster encodes a member of the mitochondrial carrier family required for gas-filling of the tracheal system and expansion of the wings after eclosion. [FBrf0099765] Royet and Finkelstein, 1997, Development 124(23): 4793--4800 Establishing primordia in the Drosophila eye-antennal imaginal disc: the roles of decapentaplegic, wingless and hedgehog. [FBrf0099885] Lecuit et al., 1996, Nature 381(6581): 387--393 Two distinct mechanisms for long-range patterning by decapentaplegic in the Drosophila wing. [FBrf0087557] Bergstrom et al., 1995, Genetics 139(3): 1331--1346 Regulatory autonomy and molecular characterization of the Drosophila out at first gene. [FBrf0079893] Diaz-Benjumea et al., 1994, Nature 372(6502): 175--179 Cell interaction between compartments establishes the proximal-distal axis of Drosophila legs. [FBrf0076987] Littleton and Bellen, 1994, Genetics 138(1): 111--123 Genetic and phenotypic analysis of thirteen essential genes in cytological interval 22F1-2; 23B1-2 reveals novel genes required for neural development in Drosophila. [FBrf0076536] Posakony et al., 1990, Mech. Dev. 33: 69--82 Wing formation in Drosophila melanogaster requires decapentaplegic gene function along the anterior-posterior compartment boundary. [FBrf0052519] Segal and Gelbart, 1985, Genetics 109: 119--143 Shortvein, a new component of the decapentaplegic gene complex in Drosophila melanogaster. [FBrf0042626] Spencer et al., 1982, Cell 28(3): 451--461 Decapentaplegic: A gene complex affecting morphogenesis in Drosophila melanogaster. [FBrf0037609]
Personal communication to FlyBase	Ly, 2005.3.2, Helping FlyBase: ADRC-50399. Helping FlyBase: ADRC-50399. [FBrf0183137] BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338] Gelbart, 1994.11.17, Df(2L)dpp<up>d33</up>. Df(2L)dpp^d33. [FBrf0075324]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]

Aberration Dmel\Df(2L)dppd14

Aberration Dmel\Df(2L)dpp^d14