Aberration Dmel\Df(2L)esc-P3-0

General Information
Symbol	Dmel\Df(2L)esc-P3-0	Species	D. melanogaster
Name		FlyBase ID	FBab0001810
Feature type	chromosomal_deletion
Also Known As	Df(2L)escP3-0

Computed Breakpoints include	33A1;33E
Deleted segment	33A1--33E
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	P-element activity
Class of aberration (relative to progenitor)	chromosomal_deletion (Pauli et al., 1995, Harbecke and Lengyel, 1995)
Breakpoints	33A1-33A2;33B1-33B2 (Pauli et al., 1995) 33A1-33A2;33E (Harbecke and Lengyel, 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << Agi << aret << bk2
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0080317) Right limit of break 1 from inclusion of salm (FBrf0047928) Limits of break 2 from polytene analysis (FBrf0082073)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Agi (Parker and Roberts, 1996) aret (Castrillon et al., 1993, Sugimura and Lilly, 2006) bft (Hardiman et al., 2002) esc (Jurgens, 1988) prd (Jurgens, 1988, Harbecke and Lengyel, 1995) salm (Barrio et al., 1999, Harbecke and Lengyel, 1995, Jurgens, 1988)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Pkd2 (Gao et al., 2004)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	The Df(2L)esc-P3-0 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Homozygous embryos do not complete head involution and tracheae and salivary glands are variable in size. (Harbecke and Lengyel, 1995) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995)
Stocks ( 2 )
Bloomington	3131 Df(2L)esc-P3-0/CyO, amos^Roi-1<P>
Kyoto	106870 Df(2L)esc-P3-0/Cy¹ amos^Roi-1
Notes on Origin
Discoverer	Struhl.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Df(2L)esc^P3-0 (Jurgens, 1988) Df(2L)escP3-0 (Hardiman et al., 2002, Ashton et al., 2001, Barrio et al., 1999, Parker and Roberts, 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Castrillon et al., 1993) Df(2L)esc-P3-0 (Sugimura and Lilly, 2006, Ohno et al., 2008, Nilton et al., 2010, Moore et al., 2009) Df(2R)esc-P3-0 (Gao et al., 2004)
Name Synonym
Secondary FlyBase IDs

References ( 20 )
Research paper	Nilton et al., 2010, Development 137(14): 2427--2437 Crooked, coiled and crimpled are three Ly6-like proteins required for proper localization of septate junction components. [FBrf0211147] Moore et al., 2009, Mech. Dev. 126(7): 503--516 Bruno negatively regulates germ cell-less expression in a BRE-independent manner. [FBrf0215430] Ohno et al., 2008, Mech. Dev. 125(5-6): 527--541 ESC, ESCL and their roles in Polycomb Group mechanisms. [FBrf0205395] Sugimura and Lilly, 2006, Dev. Cell 10(1): 127--135 Bruno inhibits the expression of mitotic cyclins during the prophase I meiotic arrest of Drosophila oocytes. [FBrf0190220] Gao et al., 2004, J. Biol. Chem. 279(14): 14225--14231 Drosophila Pkd2 is haploid-insufficient for mediating optimal smooth muscle contractility. [FBrf0174776] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Presgraves, 2003, Genetics 163(3): 955--972 A fine-scale genetic analysis of hybrid incompatibilities in Drosophila. [FBrf0158988] Hardiman et al., 2002, Genetics 161(1): 231--247 The bereft gene, a potential target of the neural selector gene cut, contributes to bristle morphogenesis. [FBrf0149016] Ashton et al., 2001, Genetics 157(1): 283--294 Quantitative trait loci for the monoamine-related traits heart rate and headless behavior in Drosophila melanogaster. [FBrf0132335] Barrio et al., 1999, Dev. Biol. 215(1): 33--47 Identification of regulatory regions driving the expression of the Drosophila spalt complex at different developmental stages. [FBrf0111797] Webster et al., 1997, Genes Dev. 11(19): 2510--2521 Translational repressor bruno plays multiple roles in development and is widely conserved. [FBrf0098905] Parker and Roberts, 1996, Biochem. Genet. 34(3-4): 117--131 AGI, a previously unreported D. melanogaster -glucosidase: Partial purification, characterization, and cytogenetic mapping. [FBrf0087652] Harbecke and Lengyel, 1995, Rouxs Arch. Dev. Biol. 204(5): 308--329 Genes controlling posterior gut development in the Drosophila embryo. [FBrf0082073] Pauli et al., 1995, Genetics 139(2): 713--732 Identification of regions interacting with ovo^D mutations: Potential new genes involved in germline sex determination or differentiation in Drosophila melanogaster. [FBrf0080317] Pauli et al., 1995, D. I. S. 76: 107--124 Dose dependent enhancers and suppressors of ovoD2. [FBrf0082455] Castrillon et al., 1993, Genetics 135(2): 489--505 Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis. [FBrf0064394] Frei et al., 1988, EMBO J. 7(1): 197--204 Molecular characterization of spalt, a homeotic gene required for head and tail development in the Drosophila embryo. [FBrf0047929] Jurgens, 1988, EMBO J. 7(1): 189--196 Head and tail development of the Drosophila embryo involves spalt, a novel homeotic gene. [FBrf0047928]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]