Aberration Dmel\Df(2L)fn5

General Information
Symbol	Dmel\Df(2L)fn5	Species	D. melanogaster
Name	Deficiency (2L) formaldehyde induced	FlyBase ID	FBab0001822
Feature type	chromosomal_deletion

Computed Breakpoints include	34F4;35C3
Deleted segment	34F4--35C3
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	formaldehyde (O'Donnell et al., 1977)
Class of aberration (relative to progenitor)	chromosomal_deletion (O'Donnell et al., 1977, Furukawa et al., 1992)
Breakpoints	34E4-34E5;35D1-35D2 (O'Donnell et al., 1977) 34F4;35C3 (Furukawa et al., 1992)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	l(2)34Fa << bk1 << wb << stc << bk2 << rd
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0055544)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Adh (O'Donnell et al., 1977, Ashburner et al., 1982, Furukawa et al., 1992) ck (O'Donnell et al., 1977, Ashburner et al., 1982, Furukawa et al., 1992) dyn-p25 (O'Donnell et al., 1977, Ashburner et al., 1982, Furukawa et al., 1992) elA (O'Donnell et al., 1977, Ashburner et al., 1982) l(2)34Fc (Ashburner et al., 1982, O'Donnell et al., 1977) l(2)34Fd (Ashburner et al., 1982, O'Donnell et al., 1977) l(2)35Bc (Furukawa et al., 1992, Ashburner et al., 1982, O'Donnell et al., 1977) l(2)35Bd (O'Donnell et al., 1977, Ashburner et al., 1982, Furukawa et al., 1992) l(2)35Be (Furukawa et al., 1992, Ashburner et al., 1982, O'Donnell et al., 1977) l(2)35Bg (O'Donnell et al., 1977, Ashburner et al., 1982, Furukawa et al., 1992) mol (O'Donnell et al., 1977, Ashburner et al., 1982, Furukawa et al., 1992) noc (O'Donnell et al., 1977, Ashburner et al., 1982) osp (Ashburner et al., 1982) pburs (O'Donnell et al., 1977, Ashburner et al., 1982) Pgant35A (O'Donnell et al., 1977, Ashburner et al., 1982) stc (Ashburner et al., 1982, Furukawa et al., 1992) Su(H) (O'Donnell et al., 1977, Ashburner et al., 1982, Furukawa et al., 1992) TfIIS (Furukawa et al., 1992) vas (Furukawa et al., 1992) wb (Ashburner et al., 1982, O'Donnell et al., 1977)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Ance (Ashburner et al., 1982) Arpc1 (Ashburner et al., 1982) b (O'Donnell et al., 1977, Ashburner et al., 1982) Cul-3 (Ashburner et al., 1982, Furukawa et al., 1992) CycE (Ashburner et al., 1982, Furukawa et al., 1992) DNApol-γ35 (Ashburner et al., 1982) esg (Furukawa et al., 1992) l(2)34Db (Ashburner et al., 1982) l(2)35Cc (Furukawa et al., 1992) l(2)35De (Furukawa et al., 1992) l(2)35Df (Furukawa et al., 1992) lace (Ashburner et al., 1982, Furukawa et al., 1992) NimA (O'Donnell et al., 1977, Ashburner et al., 1982) NimC3 (Ashburner et al., 1982) rd (O'Donnell et al., 1977, Ashburner et al., 1982, Furukawa et al., 1992) rk (O'Donnell et al., 1977, Ashburner et al., 1982) RpII33 (Ashburner et al., 1982) sna (Ashburner et al., 1982, Furukawa et al., 1992) Sos (Ashburner et al., 1982) tam (Ashburner et al., 1982) wor (Ashburner et al., 1982, Furukawa et al., 1992)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	The Df(2L)fn5 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004)
Stocks ( 2 )
Bloomington	6066 Df(2L)fn5, pr¹ cn¹/CyO, Adh^nB
Kyoto	108580 Df(2L)fn5, pr¹ cn¹/CyO, Adh^nB
Notes on Origin
Discoverer	Sofer.
	elected as ADH null on 1-penten-3-ol.
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df(2L)fn5 fn5 (Furukawa et al., 1992)
Name Synonym	Deficiency (2L) formaldehyde induced
Secondary FlyBase IDs

References ( 8 )
Research paper	Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Pasyukova et al., 2000, Genetics 156(3): 1129--1146 Deficiency mapping of quantitative trait loci affecting longevity in Drosophila melanogaster. [FBrf0131237] Furukawa et al., 1992, Cell 69: 1191--1197 The Drosophila homolog of the immunoglobulin recombination signal-binding protein regulates peripheral nervous system development. [FBrf0055544] Ashburner et al., 1990, Genetics 126: 679--694 The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase. [FBrf0051973] Ashburner et al., 1982, Genetics 102: 421--435 The genetics of a small autosomal region of Drosophila melanogaster, including the structural gene for alcohol dehydrogenase. [FBrf0038050] O'Donnell et al., 1977, Genetics 86: 553--566 Genetic and cytogenetic analysis of the Adh region in Drosophila melanogaster. [FBrf0030161]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]