FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2L)hk-UC2
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General Information
Symbol
Df(2L)hk-UC2
Species
D. melanogaster
Name
FlyBase ID
FBab0001826
Feature type
chromosomal_deletion
Computed Breakpoints include

37B2-37B8;37C5

Features within 37B2--37C5
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
spontaneous
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Stathakis et al., 1995)
Breakpoints

37B2-37B8;37C2-37C5

(Stathakis et al., 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

l(2)37Bi << bk1 << hk << l(2)37Cb << bk2 << l(2)37Cd

Genetic mapping information
Comments

This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).

(Marygold et al., 2007)

Breakpoint(s) molecularly mapped

(Stathakis, 1991, Pentz et al., 1986)

Right breakpoint at +8.15 to +10.95 to the right of Ddc (-0.06 to +3.76).

Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0084402) Left limit of break 2 from inclusion of l(2)37Cb (FBrf0084402) Right limit of break 2 from polytene analysis (FBrf0084402)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Flies heterozygous for the deletion do not show a Minute bristle phenotype.

    (Marygold et al., 2007)

    The Df(2L)hk-UC2 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    (Mason et al., 2004)
    Stocks (2)
    Notes on Origin
    Discoverer

    Gibbs and Marsh.

     

    From 15 generations of repeated backcrossing of Canton-S males to M strain females homozygous for nub b rdo hk pr cn.

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    37C2-37C5 breakpoint is between position +10.3 and +11.0 on the Ddc map relative to the HpaI restriction site near the 3' end of Ddc.

    (Stathakis et al., 1995)
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Df(2L)hk-UC2
    Df(2L)hkUC2
    (Wright, 1996)
    Name Synonyms
    Secondary FlyBase IDs
      References (11)