Aberration Dmel\Df(2L)net-PM47C

General Information
Symbol	Dmel\Df(2L)net-PM47C	Species	D. melanogaster
Name		FlyBase ID	FBab0001852
Feature type	chromosomal_deletion

Computed Breakpoints include	21A1;21B6-21B7
Deleted segment	21A1--21B7
Sequence coordinates
Recent Updates
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion (Prout et al., 1997)
Breakpoints	21A1;21B6-21B7 (Prout et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << net << Gs1 << bk2 << kis
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0093664)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Aac11 (BDGP Project Members, 1994-1999) bub (Prout et al., 1997) l(2)04207a (BDGP Project Members, 1994-1999) net (LaJeunesse et al., 2001) spen (Staehling-Hampton et al., 1999, Rebay et al., 2000, BDGP Project Members, 1994-1999, Eun et al., 2007)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Hop (BDGP Project Members, 1994-1999) kis (Daubresse et al., 1999, BDGP Project Members, 1994-1999) l(2)k01206 (BDGP Project Members, 1994-1999) l(2)k06019 (BDGP Project Members, 1994-1999) l(2)k10003a (BDGP Project Members, 1994-1999) l(2)k10111 (BDGP Project Members, 1994-1999) l(2)k10237 (BDGP Project Members, 1994-1999) l(2)k13604 (BDGP Project Members, 1994-1999) numb (BDGP Project Members, 1994-1999) Rpp30 (BDGP Project Members, 1994-1999) α-Adaptin (BDGP Project Members, 1994-1999)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Stocks ( 2 )
Bloomington	3636 Df(2L)net-PM47C/SM6a
Kyoto	107145 Df(2L)net-PM47C/SM6a
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The Df(2L)net-PM47C chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but this is assumed to be a false positive result (the suppressor may not be within the bounds of the deficient region) because the 2L TAS array on the chromosome is missing or reduced (as assayed by in situ hybridization) and it has previously been shown (FBrf0137248, FBrf0158986) that partial or complete deficiency of the 2L TAS array on the homologue suppresses silencing of brown-red variants of P{3'WP-2,w^var}2Lt. (Mason et al., 2004)
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df(2L)net-PM47C (Eun et al., 2007) Df(2L)PM47C (Caggese et al., 1988, ) Df(2L)PMF47c (LaJeunesse et al., 2001, Rebay et al., 2000)
Name Synonym
Secondary FlyBase IDs

References ( 12 )
Research paper	Eun et al., 2007, Genetics 175(3): 1163--1174 Identification of genes that interact with Drosophila liquid facets. [FBrf0200036] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] LaJeunesse et al., 2001, Genetics 158(2): 667--679 A Systematic screen for dominant second-site modifiers of Merlin/NF2 Phenotypes reveals an interaction with blistered/DSRF and scribbler. [FBrf0136951] Rebay et al., 2000, Genetics 154(2): 695--712 A genetic screen for novel components of the Ras/Mitogen-activated protein kinase signaling pathway that interact with the yan gene of Drosophila identifies split ends, a new RNA recognition motif-containing protein. [FBrf0125429] Daubresse et al., 1999, Development 126(6): 1175--1187 The Drosophila kismet gene is related to chromatin-remodeling factors and is required for both segmentation and segment identity. [FBrf0107669] Staehling-Hampton et al., 1999, Genetics 153(1): 275--287 A genetic screen for modifiers of E2F in Drosophila melanogaster. [FBrf0111491] Prout et al., 1997, Genetics 146(1): 275--285 Autosomal mutations affecting adhesion between wing surfaces in Drosophila melanogaster. [FBrf0093664] Caggese et al., 1988, Biochem. Genet. 26(9--10): 571--584 Genetic determinants of glutamine synthetase in Drosophila melanogaster: a gene for glutamine synthetase I resides in the 21B3-6 region. [FBrf0047556]
Abstract	Sakamoto et al., 2001, A. Dros. Res. Conf. 42: 745A spen/MINT negatively regulates transcription in Notch signaling pathway. [FBrf0133580]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Computer file	BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0067338]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]