FlyBase Aberration Report: Dmel\Df(2R)44CE

General Information

Symbol

Df(2R)44CE

Species

D. melanogaster

Name

FlyBase ID

FBab0001930

Feature type

chromosomal_deletion

Computed Breakpoints include

Features within 44C1--44E4

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

2Lt - 44B9 | 44C3 - 44D2 | 44F1 - 2Rt

(Kumar et al., 2001)

Progenitor

Mutagen

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Kumar et al., 2001, Lindsley and Zimm, 1992, Hooper and Scott, 1989)

Breakpoints

44C;44E1-44E4

(Lindsley and Zimm, 1992, Hooper and Scott, 1989)

44B9-44C1;44C2-44C3;44D2-44D3;44E4-44F1

(Kumar et al., 2001)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

Genetic mapping information

Comments

Breakpoint(s) molecularly mapped

(Hooper and Scott, 1989)

Comments on Cytology

The Df(2R)44CE deficiency, previously thought to be a simple two break event is, on closer inspection, a four break event resulting in two closely linked deficiencies. Deleted segments are 44C1--44C2 and 44D3--44E4.

(Kumar et al., 2001)

FlyBase curator comment: See FBrf0144960 for further description of cytology.

(Lindsley and Zimm, 1992, Hooper and Scott, 1989)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Acsl

(Mohr and Boswell, 2002, Spradling et al., 1999, BDGP Project Members, 1994-1999)

dpn

(Barbash and Cline, 1995)

l(2)44CDa

(Mohr and Boswell, 2002)

l(2)44Da

(Dockendorff et al., 2000)

l(2)44Dc

(Dockendorff et al., 2000)

l(2)44Dd

(Dockendorff et al., 2000)

l(2)44Ea

(Dockendorff et al., 2000)

l(2)k03110

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)s1878

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

pnut

(Spradling et al., 1999, BDGP Project Members, 1994-1999, Neufeld and Rubin, 1994)

ptc

(Vegh and Basler, 2003, Dockendorff et al., 2000, Spradling et al., 1999, Zhang et al., 1996, Kania et al., 1995, BDGP Project Members, 1994-1999, Hooper, 1994, Lindsley and Zimm, 1992, Hooper and Scott, 1989)

Vps25

(Dockendorff et al., 2000, Spradling et al., 1999, BDGP Project Members, 1994-1999)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Ak2

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

babo

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

cri

(Mohr and Boswell, 2002)

CSN4

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

dap

(BDGP Project Members, 1994-1999)

flz

(Mohr and Boswell, 2002)

Gγ1

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

kermit

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)44Fl

(Mohr and Boswell, 2002)

l(2)44Fm

(Mohr and Boswell, 2002)

l(2)44Fn

(Mohr and Boswell, 2002)

l(2)44Fo

(Mohr and Boswell, 2002)

l(2)44Fp

(Mohr and Boswell, 2002)

l(2)45Ab

(Mohr and Boswell, 2002)

l(2)45Ah

(Mohr and Boswell, 2002)

l(2)45Aj

(Mohr and Boswell, 2002)

l(2)45An

(Mohr and Boswell, 2002)

l(2)45Ao

(Mohr and Boswell, 2002)

l(2)45Ap

(Mohr and Boswell, 2002)

l(2)45Aq

(Mohr and Boswell, 2002)

l(2)45Ar

(Mohr and Boswell, 2002)

l(2)45As

(Mohr and Boswell, 2002)

l(2)k07521

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)k08807

(BDGP Project Members, 1994-1999)

lin

(Mohr and Boswell, 2002)

Rho1

(BDGP Project Members, 1994-1999)

Rs1

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

RyR

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

sip

(Mohr and Boswell, 2002)

stmA

(Kumar et al., 2001)

tsu

(Mohr and Boswell, 2002)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

Df(2R)44CE/In(2LR)TE35B-14^LSco^rv1R lethal Df(2R)44CE/In(2LR)TE35B-15^LTE45F^R lethal

(Hooper and Scott, 1989)

NOT in combination with other aberrations

The Df(2R)44CE chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(2R)44CE results in 8.1% X chromosome nondisjunction and 3.5% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females.

(Harris et al., 2003)

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpp^hr4.

(Nicholls and Gelbart, 1998)

Homozygotes show unusually disperse germ cells. Heterozygotes with Df(2R)cn9 exhibit aberrant migration of the germ cell. Homozygotes also exhibit segment polarity phenotype of ptc.

(Zhang et al., 1996)

Dominantly suppresses female-specific lethality of sc^sisB-1 and da¹ mutations.

(Barbash and Cline, 1995)

Midgut development of mutant embryos is wild type.

(Bilder and Scott, 1995)

Stocks (3)

Bloomington

3643

Df(2R)44CE, In(2R)46C, al¹ dpy^ov1 Adc^b-1 pr¹/CyO

Kyoto

107152

Df(2R)44CE, al¹ dpy^ov1 Adc^b-1 pr¹/CyO

101434

Df(2R)44CE, al¹ dpy^ov1 Adc^b-1 pr¹ / CyO, Duox^Cy dpy^lv1 pr¹ cn²

Notes on Origin

Discoverer

Yannopoulos.

(Lindsley and Zimm, 1992)

Associated with: wun^CE.

(Zhang et al., 1996)

Separable from: In(2R)46C. The Df(2R)44CE chromosome carries the In(2R)46C inversion.

(Zhang, 1994.9)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

"44B9--C1;44C2--3;44D2--3;44E4--F1" was stated as revision.

(Kumar et al., 2001)

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Df 44Ce

(Garver et al., 2006)

Df(2R)44C-E

(Bokor and DiNardo, 1996)

Df(2R)44CE

(Casso et al., 2008, Crest et al., 2007)

ptc^CE

(Ramirez-Weber et al., 2001)

ptc^Df(2R)44CE

(Alcedo et al., 2000)

Name Synonyms

Secondary FlyBase IDs

References (36)

Report Sections

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