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General Information
Symbol
Df(2R)B
Species
D. melanogaster
Name
FlyBase ID
FBab0001940
Feature type
Computed Breakpoints include

[h39--h41];[h41]

Deleted Segment
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

Rsp << bk1 << l(2)41Ab << l(2)41Aa << bk2 << rl

Genetic mapping information
Comments
Comments on Cytology

Left limit of break 1 from non-inclusion of Rsp (citation unavailable) Right limit of break 1 from inclusion of l(2)41Aa (citation unavailable) Left limit of break 2 from inclusion of l(2)41Aa (citation unavailable) Right limit of break 2 from non-inclusion of rl (citation unavailable)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Phenotypic Data
In combination with other aberrations

Df(2R)B/Df(2R)IR7 mutant larvae have abnormal wing discs. Df(2R)B/Df(2R)IR7 mutant larval neuroblast cells exhibit a higher anaphase/metaphase ratio than wild-type cells. The total number of Df(2R)B/Df(2R)IR7 larval neuroblast cells undergoing mitosis is reduced compared to wild-type cells (mitotic index of 0.41 vs 0.81). 25% of Df(2R)B/Df(2R)IR7 mutant larval spermatids carry micronuclei. 12% of Df(2R)IR7/Df(2R)B mutant larval spermatids have large Nebenkerns associated with either two or four nuclei or micronuclei. In 30% of Df(2R)IR7/Df(2R)B mutant larval spermatids, bivalents do not condense properly and chromatin filaments are visible along the three major dots of chromatin. In Df(2R)B/Df(2R)IR7 mutant larval spermatids, 28% of chromosomes are seen to be lagging during anaphase/telophase I, while 21% lag during anaphase/telophase II.

Df(2R)B/Df(2R)M41A4 viable (Hilliker, 1976) Df(2R)B/Df(2R)M41A8 viable (Hilliker, 1976) Df(2R)B/Df(2R)M41A10 lethal (Hilliker, 1976)

NOT in combination with other aberrations

83% of Df(2R)B/Df(2R)B mutant larvae show abnormally condensed chromosomes. In Df(2R)B/Df(2R)B mutants, the total number of larval neuroblast cells undergoing mitosis is reduced (mitotic index of 0.2 vs 0.81 for wild-types).

Stocks (0)
Notes on Origin
Discoverer
 

reconstitution of chromosome 2 by detachment of compound second chromosomes (Hilliker and Holm, 1975).

Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

Group B deficiencies have been generated from the progenitor genotype of C(2L)RM-SH3 in combination with C(2R)RM-SH3.

Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (7)