|Name||Deficiency (2R) Epidermal growth factor||FlyBase ID||FBab0001959|
|Also Known As||egfr3F18, flb3F18, DER3F18|
|Computed Breakpoints include||57E1;57F5-57F10|
|Member of large scale dataset(s)|
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|Nature of the Aberration|
|Class of aberration (relative to progenitor)|
|Formalized genetic data||bk1 << l(2)57Eb << bk2|
|Genetic mapping information|
|Comments on Cytology|
Ref: Price et al., 1989, Cell 56: 1085--1092
|Gene Deletion & Duplication Data|
|Genes Deleted / Disrupted|
|Completely deleted / disrupted|
|Genes NOT Deleted / Disrupted|
|Genes NOT Duplicated|
|In combination with other aberrations|
|NOT in combination with other aberrations|
Egfrf3/Df(2R)Egfr3 embryos exhibit no ventral cuticle and the anterior has a large hole. No Egfrf3/Df(2R)Egfr3 mutant discs could be in vivo cultured.
Homozygotes and hemizygotes display a severe 'flb' phenotype.
Abdominal denticle belts and head skeleton are almost absent. Germ band has not retracted and the cuticle size is much reduced.
Severe lethal phenotype: anterior structures deteriorate, ventral denticle bands are missing, germ band does not retract and the CNS shows a collapse of commissure and midline pattern.
|Stocks ( 2 )|
|Notes on Origin|
|Balancer / Genotype Variants of the Aberration|
|Synonyms & Secondary IDs ( 13 )|
Deficiency (2R) Epidermal growth factor
|Secondary FlyBase IDs|
|References ( 17 )|