FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2R)Egfr5
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General Information
Symbol
Df(2R)Egfr5
Species
D. melanogaster
Name
Deficiency (2R) Epidermal growth factor
FlyBase ID
FBab0001960
Feature type
chromosomal_deletion
Computed Breakpoints include

57D2-57D8;58D1

Features within 57D2--58D1
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
gamma ray
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Price, 1999.5.25)
Breakpoints

57D2-57D8;58D1

(Price, 1999.5.25)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << l(2)57Db << l(2)57Eb << bk2

Genetic mapping information
Comments
Comments on Cytology

All limits from polytene analysis (citation unavailable)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Egfr
(Price et al., 1989)
l(2)57Db
(Price et al., 1989)
l(2)57Eb
(Price et al., 1989)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    The Df(2R)Egfr5 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    (Mason et al., 2004)

    Behaves phenotypically as a severe Egfr point mutation.

    (Price et al., 1989)
    Stocks (2)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (9)
    Reported As
    Symbol Synonym
    Df(2R)Egfr
    (Muhammad et al., 2008)
    Df(2R)Egfr5
    (Muraoka et al., 2018, Galindo et al., 2014, Fernandes and Rao, 2011)
    Df(2R)Egfr5D
    Df(2R)Egfr5D
    DfVPS35
    (Muhammad et al., 2008)
    Egfrtop-5D
    In(2R)top5D
    (Price et al., 1989)
    top5D
    (Price et al., 1989)
    Name Synonyms
    Deficiency (2R) Epidermal growth factor
    Secondary FlyBase IDs
    • FBal0029756
    References (17)