h44-h46;h46-41A3
41A;41A
41C;41F8-41F9
uex << bk1 << l(2)IR4 << stw << bk2 << ap
This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).
The z1 In(1)wis eye colour phenotype is enhanced by Df(2R)M41A8.
Lethal in combination with Df(2R)M41A4 or Df(2R)M41A10.
Lethal in combination with Df(2R)M41A10.
Flies heterozygous for the deletion show a Minute bristle phenotype.
Strongly (over 4-fold) enhances the ct53d cut wing phenotype.
Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.
Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovoD2.
Heterozygotes show a Minute phenotype. Homozygous lethal.
homozygous lethal Long-bristled Minute; readily classifiable. Pale body color. Eyes often deformed; postscutellar bristles may be erect or absent.
The Df(2R)M41A8 chromosome acts as a dominant moderate suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is assumed to be a false positive result (the suppressor may not be within the bounds of the deficient region) because the 2L TAS array on the chromosome is missing (as assayed by in situ hybridization) and it has previously been shown (FBrf0137248, FBrf0158986) that partial or complete deficiency of the 2L TAS array on the homologue suppresses silencing of brown-red variants of P{3'WP-2,wvar}2Lt. In addition, the deficiency chromosome fails to complement lethal mutations of l(2)gl and deficiencies that are mutant for l(2)gl are often also deficient for the 2L TAS array (FBrf0137248).
Left limit of break 1 from non-inclusion of uex (FBrf0042654) Right limit of break 1 from inclusion of l(2)41Ae (FBrf0027524) Left limit of break 2 from inclusion of RpL38 (FBrf0027524) Right limit of break 2 from polytene analysis (FBrf0080317)