Aberration Dmel\Df(2R)PC29

General Information
Symbol	Dmel\Df(2R)PC29	Species	D. melanogaster
Name		FlyBase ID	FBab0002013
Feature type	chromosomal_deletion
Also Known As	Df(2R)P29, Df(2R)Pu29

Computed Breakpoints include	55C1-55C2;56B1-56B2
Deleted segment	55C1--56B2
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	Tp(1;2)TE55Ea (Bloomington Drosophila Stock Center, 1999.7.2)
Mutagen	X ray (Bloomington Drosophila Stock Center, 1999.7.2)
Class of aberration (relative to progenitor)	chromosomal_deletion (Lindsley and Zimm, 1992, Tearle, 1996.5.14, Doane and Dumapias, 1987, Beaton, 1997.3.4, Bloomington Drosophila Stock Center, 1999.7.2)
Breakpoints	55C1-55C2;56B1-56B2 (Doane and Dumapias, 1987, Lindsley and Zimm, 1992, Tearle, 1996.5.14, Beaton, 1997.3.4, Bloomington Drosophila Stock Center, 1999.7.2)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	adp << bk1 << l(2)PC4-R << l(2)PC4-P << bk2 << prod
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0086812)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	edl (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)03709 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)08717 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)08770 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)PC4-P (Tearle, 1996.5.14) l(2)PC4-Q (Tearle, 1996.5.14) l(2)PC4-R (Tearle, 1996.5.14) l(2)PC4-S (Tearle, 1996.5.14) Prp19 (Spradling et al., 1999, BDGP Project Members, 1994-1999) sbb (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	adp (Doane, 1999, Doane and Dumapias, 1987, Doane, 1996) ena (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(2)k06106 (BDGP Project Members, 1994-1999) l(2)k09021 (BDGP Project Members, 1994-1999) l(2)s1864 (BDGP Project Members, 1994-1999) mama (Doane, 1999) pAbp (Spradling et al., 1999, BDGP Project Members, 1994-1999) prod (Spradling et al., 1999, BDGP Project Members, 1994-1999, Beaton, 1997.3.4) rib (Shim et al., 2001) sbb (Senti et al., 2000) sub (Giunta et al., 2002)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Fails to complement Df(2R)PC4, Df(2R)P34 and Df(2R)PC66; complements Df(2R)Pcl^XM82, Df(2R)Pcl7B and Df(2R)Pcl11B. (Tearle, 1996.5.14)
NOT in combination with other aberrations
Stocks ( 3 )
Bloomington	5243 y¹ w^*/Dp(1;Y)y⁺; Df(2R)PC29/CyO
Kyoto	108114 y¹ w^/Dp(1;Y)y⁺; Df(2R)PC29/CyO 101872 y^ w^* / Dp(1;Y)y⁺ ; Df(2R)PC29 / CyO
Notes on Origin
Discoverer	R. Karp (Bloomington Drosophila Stock Center, 1999.7.2)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The Df(2R)PC29 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by a combination of nonsuppressing deficiencies and deficiencies with suppressors that map to the 2L tip. (Mason et al., 2004)
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Df(2R)C29 (Mason et al., 2004) Df(2R)P29 (Doane, 1996, Doane and Dumapias, 1987, Doane, 1994, ) Df(2R)PC29 Df(2R)Pu29 (Bloomington Drosophila Stock Center, 1999.7.2, Tearle, 1996.5.14)
Name Synonym
Secondary FlyBase IDs

References ( 18 )
Research paper	Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Presgraves, 2003, Genetics 163(3): 955--972 A fine-scale genetic analysis of hybrid incompatibilities in Drosophila. [FBrf0158988] Giunta et al., 2002, Genetics 160(4): 1489--1501 subito encodes a kinesin-like protein required for meiotic spindle pole formation in Drosophila melanogaster. [FBrf0147060] Ashton et al., 2001, Genetics 157(1): 283--294 Quantitative trait loci for the monoamine-related traits heart rate and headless behavior in Drosophila melanogaster. [FBrf0132335] Shim et al., 2001, Development 128(23): 4923--4933 The Drosophila ribbon gene encodes a nuclear BTB domain protein that promotes epithelial migration and morphogenesis. [FBrf0141499] Yedvobnick et al., 2001, genesis 30(4): 250--258 Identification of chromosomal deficiencies that modify Drosophila mastermind mutant phenotypes. [FBrf0138541] Senti et al., 2000, Development 127(11): 2291--2301 brakeless is required for lamina targeting of R1-R6 axons in the Drosophila visual system. [FBrf0127316] Doane, 1999, D. I. S. 82: 53--56 Why is mama not adipose? [FBrf0111850] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489] Doane, 1996, D. I. S. 77: 78--79 The adp^fs and fs(2)lto5 mutations of Drosophila melanogaster show allelic interactions. [FBrf0091429] Doane, 1994, D. I. S. 75: 168 The adipose gene is located in section 55A of chromosome 2R. [FBrf0072971] Doane and Dumapias, 1987, D. I. S. 66: 49 Deletion limits of the adp, map and nw loci in D. melanogaster. [FBrf0045962]
Personal communication to FlyBase	Bloomington Drosophila Stock Center, 1999.7.2, Karp and Cherbas deletions and point mutations. Karp and Cherbas deletions and point mutations. [FBrf0108617] Beaton, 1997.3.4, Update: Deficiencies. Update: Deficiencies. [FBrf0092781] Tearle, 1996.5.14, [title not yet available] [title not yet available] [FBrf0086812] BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]