FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2R)Pu-D17
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General Information
Symbol
Df(2R)Pu-D17
Species
D. melanogaster
Name
FlyBase ID
FBab0002024
Feature type
chromosomal_deletion
Also Known As
Df(2R)PuD17, Df(2R)D17, PuD17
Computed Breakpoints include

57B4;58B1-58B2

Features within 57B4--58B2
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
gamma ray
(O'Donnell et al., 1989)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Duffy et al., 1996, Harbecke and Lengyel, 1995, Kania et al., 1995, Pauli et al., 1995, Landecker et al., 1994, Castrillon et al., 1993, Boswell et al., 1991, Schupbach and Wieschaus, 1991, Baker and Rubin, 1989, Schupbach and Wieschaus, 1989)
Breakpoints

57B4;58B

(Duffy et al., 1996, Harbecke and Lengyel, 1995, Kania et al., 1995, Landecker et al., 1994, Castrillon et al., 1993, Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989)

57B5;58B1-58B2

(Pauli et al., 1995, Boswell et al., 1991, Baker and Rubin, 1989)

57B5--57B6;[]

(Uemura et al., 1996)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

insc << bk1 << prat << l(2)07837 << bk2 << dve

Genetic mapping information
Comments

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

(Marygold et al., 2007)
Comments on Cytology

Ref: Lindsley and Zimm, 1992

(Kania et al., 1995)

Limits of break 1 from polytene analysis (FBrf0049878) Limits of break 2 from polytene analysis (FBrf0050618)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
cpa
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
dom
(Ruhf et al., 2001, Braun et al., 1997, BDGP Project Members, 1994-1999)
Egfr
(Liu et al., 1999, Spradling et al., 1999, Verheyen et al., 1996, Harbecke and Lengyel, 1995, BDGP Project Members, 1994-1999, Baker and Rubin, 1989, O'Donnell et al., 1989)
Fkbp14
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
grau
(Chen et al., 2000, Page and Orr-Weaver, 1996, Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989)
insc
(Kania et al., 1995, BDGP Project Members, 1994-1999)
l(2)57Ba
(O'Donnell et al., 1989)
l(2)57Bb
(O'Donnell et al., 1989)
l(2)57Bc
(O'Donnell et al., 1989)
l(2)57Bd
(O'Donnell et al., 1989)
l(2)57Cb
(O'Donnell et al., 1989)
l(2)57Cc
(O'Donnell et al., 1989)
l(2)57Cd
(O'Donnell et al., 1989)
l(2)57Ce
(O'Donnell et al., 1989)
l(2)57Da
(O'Donnell et al., 1989)
l(2)57Db
(O'Donnell et al., 1989)
l(2)57Dc
(O'Donnell et al., 1989)
l(2)57Eb
(O'Donnell et al., 1989)
l(2)57Ec
(O'Donnell et al., 1989)
l(2)k05614
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
l(2)k07204
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
l(2)k10317
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
mago
(Boswell et al., 1991, O'Donnell et al., 1989)
mat(2)N
(Schupbach and Wieschaus, 1991, O'Donnell et al., 1989, Schupbach and Wieschaus, 1989)
MESK2
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
pratf
(Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989)
Pu
(Sugaya and Fuyama, 1995, O'Donnell et al., 1989, O'Donnell et al., 1989)
Sdc
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
shg
(Spradling et al., 1999, Tepass et al., 1996, Uemura et al., 1996, BDGP Project Members, 1994-1999)
sktl
(Spradling et al., 1999)
tmx
(Castrillon et al., 1993)
tud
(O'Donnell et al., 1989, Schupbach and Wieschaus, 1989, Schupbach and Wieschaus, 1986)
Xbp1
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
Partially deleted / disrupted
Molecular Data
Completely deleted
CG10527
(Burtenshaw et al., 2008)
mRpL54
(Marygold et al., 2007)
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Lethal in combination with Df(2R)BSC814.

    (Kahsai et al., 2016)

    Loss of the anterior crossvein is seen in 41% of Df(2R)Pu-D17 Df(2R)en-SFX31 double heterozygous flies.

    (Layalle et al., 2011)

    The penetrance of the extra sex comb teeth phenotype seen in Df(3L)Pc flies is suppressed by Df(2R)Pu-D17.

    (Gildea et al., 2000)

    Df(2R)E2/Df(2R)Pu-D17 transheterozygotes show gross disorganization of epithelial tissues in the head, ventral epidermis, Malpighian tubules and tracheal ducts. Malpighian tubule tip cells are present and differentiate into neurons, as in wild type. Phenotype is alleviated by shghs.PU.

    (Uemura et al., 1996)
    NOT in combination with other aberrations

    Df(2R)Pu-D17 animals show reduced lifespan compared to controls.

    (Burtenshaw et al., 2008)

    Flies heterozygous for the deletion do not show a Minute bristle phenotype.

    (Marygold et al., 2007)

    The Df(2R)Pu-D17 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    (Mason et al., 2004)

    Heterozygotes show a quantitative effect on wing shape in intervein regions B, C and D compared to wild type.

    (Palsson and Gibson, 2000)

    Homozygotes die during late embryogenesis with a defect in the ventral region.

    (Reynaud et al., 1999)

    Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

    (Coyne et al., 1998)

    No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

    (Halsell and Kiehart, 1998)

    Shows no maternal enhancement of dpphr4.

    (Nicholls and Gelbart, 1998)

    Does not uncover Dsim\jba in D.melanogaster/D.simulans hybrids. Uncovers Dsim\pm in D.melanogaster/D.simulans hybrids.

    (Yamamoto et al., 1997)

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    (Duffy et al., 1996)

    Deficient embryos show an uninterpretable mutant midgut phenotype.

    (Bilder and Scott, 1995)

    Homozygous embryos are very abnormal compared to wild-type.

    (Harbecke and Lengyel, 1995)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    Severe morphological defect.

    (Smith et al., 1993)
    Stocks (4)
    Notes on Origin
    Discoverer

    O'Donnell.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (12)
    References (71)