FB2020_06, released Dec 22, 2020

Aberration: Dmel\Df(2R)Px1

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General Information
Symbol
Df(2R)Px1
Species
D. melanogaster
Name
Deficiency (2R) Plexate
FlyBase ID
FBab0002026
Feature type
chromosomal_deletion
Also Known As
Df(2R)Px
Computed Breakpoints include

60B8-60B10;60D1

Features within 60B8--60D1
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
spontaneous
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Wang et al., 1997, Pauli et al., 1995, Ludwig et al., 1991, Peng and Mount, 1990, Sunkel and Whittle, 1987)
Breakpoints

60B;60D1

(Sunkel and Whittle, 1987)

60B8-60B10;60D1-60D2

(Wang et al., 1997, Pauli et al., 1995, Ludwig et al., 1991, Peng and Mount, 1990)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

Dat << bk1 << l(2)NS << Pin << bk2 << Dll

Genetic mapping information
Comments
Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0051917) Limits of break 2 from polytene analysis (FBrf0047276)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
bs
(Guillemin et al., 1996, Affolter et al., 1994, Bridges, 1937)
ifm(2)RU3
(Babu and Ramachandra, 2007, Nongthomba and Ramachandra, 1999)
speck
(Peng and Mount, 1990, Bridges, 1937)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Lethal in combination with Df(2R)Px5.

    (Thompson, 1963)

    Df(2R)Px1/Df(2R)Px2 lethal Df(2R)Px1/Df(2R)Px5 lethal

    NOT in combination with other aberrations

    The Df(2R)Px1 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    (Mason et al., 2004)

    The tracheal phenotypes previously reported for this deficiency in FBrf0051997 and FBrf0072461, where the primary branches are disrupted and discontinuous, are due to the deletion of a gene other than bs, or more than one gene in the region.

    (Guillemin et al., 1996)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    Wing veins of heterozygote with px-like or Dl-like thickenings, most often near posterior crossvein and free fragments of vein, most often in third posterior cell; L4 vein bent near margin. Wings smaller and narrower than wild type and dusky textured. Closely resembles bs. Expression more extreme in female; enhanced by cold (19o). homozygous lethal as embryo (Li, 1927).

    Stocks (0)
    Notes on Origin
    Discoverer

    Bridges, 6th June 1922.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Complementation tests reported for Df(2R)Px1 may have used a Df(2R)Px2 stock. The Mid-America Stock Center stock 1779 and the Bloomington Stock Center stock 750, which were labeled Df(2R)Px1, were in fact Df(2R)Px2 stocks. The mix-up predates 1991.

    (Bloomington Drosophila Stock Center, 2003.8.1)

    FlyBase curator comment: See personal communication from Bloomington Drosophila Stock Center, 2003.8.1, for note about possible confusion between Df(2R)Px1 and Df(2R)Px2 stocks.

    (Krishnan and Basole, 1999.4.2, Nongthomba and Ramachandra, 1999, Wang et al., 1997, Guillemin et al., 1996, Pauli et al., 1995, Affolter et al., 1994, Ludwig et al., 1991, Peng and Mount, 1990, Sunkel and Whittle, 1987, Jackson et al., 1985, Huntley, 1978, Bridges, 1937)
    Synonyms and Secondary IDs (7)
    References (28)