FB2022_02, released March 29, 2022

Aberration: Dmel\Df(2R)ST1

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General Information
Symbol
Df(2R)ST1
Species
D. melanogaster
Name
FlyBase ID
FBab0002037
Feature type
chromosomal_deletion
Also Known As
Df(2R)ST1, noc3, Df(2R)1888
Computed Breakpoints include

42B3-42B4;43E18

Features within 42B3--43E18
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
gamma ray
(Ashburner et al., 1981)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Holmes et al., 1998, Rodriguez et al., 1996, Feger et al., 1995, Pauli et al., 1995, Cheyette et al., 1994, Landecker et al., 1994, Chandrashekaran and Sarla, 1993, Heitzler et al., 1993, Schupbach and Wieschaus, 1991, Grau and Simpson, 1987, Gubb et al., 1985, Ashburner et al., 1981)
Breakpoints

43B3-43B5;43E18

(Gubb et al., 1985, Ashburner et al., 1981)

42B3-42B4;43E18

(Feger et al., 1995)

43B3-43B5;43E15-43E18

(Holmes et al., 1998)

43B3-43B5;43E1-43E8

(Pauli et al., 1995, Cheyette et al., 1994, Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989, Grau and Simpson, 1987)

42B3-42B5;43E15-43E18

(Heitzler et al., 1993)

43B3;43E18

(Chandrashekaran and Sarla, 1993)

43B3-43B4;43E18

(Rodriguez et al., 1996, Landecker et al., 1994)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

stmA << bk1 << rambl << bk2

Genetic mapping information
Comments

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

(Marygold et al., 2007)
Comments on Cytology

Ref: Bloomington Stock Centre.

(Cheyette et al., 1994)

Ref: Ashburner et al., 1981, D. I. S. 56: 186--191.

(Heitzler et al., 1993)

Ref: Lindsley and Zimm, 1987, D. I. S. 65: 1--224

(Schupbach and Wieschaus, 1991)

Left limit of break 1 from polytene analysis (FBrf0058613) Right limit of break 1 from polytene analysis (FBrf0085022) Limits of break 2 from polytene analysis (FBrf0036112)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Aldh-III
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
Bap170
(Rendina et al., 2010)
blow
(Eeken et al., 2001)
boca
(Eeken et al., 2001)
CanB2
(Gajewski et al., 2003)
cn
(Eeken et al., 2001, Ashburner et al., 1981)
cos
(Spradling et al., 1999, BDGP Project Members, 1994-1999, Grau and Simpson, 1987)
Cyt-b5
(Spradling et al., 1999, Kimbrell, 1996.4.28, Rodriguez et al., 1996, BDGP Project Members, 1994-1999)
Dscam1
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
Eb1
(Brumby et al., 2004, Spradling et al., 1999)
Egfr
(Eeken et al., 2001)
fs(2)43Ei
(Eeken et al., 2001)
fs(2)ltoRN73
(Schupbach and Wieschaus, 1991)
geminin
(Quinn et al., 2001)
jing
(Sedaghat et al., 2002, Liu and Montell, 2001)
l(2)43Bb
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
l(2)43Ef
(Eeken et al., 2001)
l(2)43Eg
(Eeken et al., 2001)
l(2)43Eh
(Eeken et al., 2001)
l(2)08492
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
Mccc2
(BDGP Project Members, 1994-1999)
Orc1
(Schupbach and Wieschaus, 1991)
pk
(Ashburner et al., 1981)
rambl
(Holmes et al., 1998)
Rpt1
(Eeken et al., 2001, BDGP Project Members, 1994-1999)
scra
(Eeken et al., 2001, Spradling et al., 1999, BDGP Project Members, 1994-1999, Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989)
so
(Ashburner et al., 1981)
Tdc1
(Cole et al., 2005)
Tdc2
(Cole et al., 2005)
tor
(Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989)
U2A
(Eeken et al., 2001)
Partially deleted / disrupted
Molecular Data
Completely deleted
mRpL52
(Marygold et al., 2007)
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    No effect on In(1)wm4h position-effect variegation.

    (Wustmann et al., 1989)
    NOT in combination with other aberrations

    Flies heterozygous for the deletion do not show a Minute bristle phenotype.

    (Marygold et al., 2007)

    Heterozygosity for Df(2R)ST1 results in 1.9% X chromosome nondisjunction and 0.8% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

    (Harris et al., 2003)

    Homozygotes exhibit tracheal defects, with losses of the dorsal drunk, severely disrupted transverse connectives and absences of the visceral branch.

    (Sedaghat et al., 2002)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    The ocelli are reduced in size. The number of anterior postalar bristles and ocellar bristles are reduced. The pattern of the interocellar microchaetae is disturbed.

    (Ashburner et al., 1981)

    Heterozygotes have small ocelli (Ashburner).

    Stocks (3)
    Notes on Origin
    Discoverer

    S.I. Tsubota.

    (Ashburner et al., 1981)

    Tsubota.

     

    The stock contains a second-site deletion uncovering l(2)gl.

    (Roegiers et al., 2009)
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2R)ST1 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

    (Mason et al., 2004)

    Mistakenly interpreted as carrying a noc allele induced simultaneously.

    (Gubb et al., 1985, Ashburner et al., 1981)

    mistakenly interpreted as carrying a noc allele induced simultaneously

    (Ashburner et al., 1982)
    Synonyms and Secondary IDs (10)
    References (59)