Aberration Dmel\Df(2R)Su(z)2⁵

General Information
Symbol	Dmel\Df(2R)Su(z)2⁵	Species	D. melanogaster
Name		FlyBase ID	FBab0002038
Feature type	chromosomal_deletion
Also Known As	Su(z)2⁵

Computed Breakpoints include	49D2-49D6;49E6-49F2
Deleted segment	49D2--49F2
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	gamma ray (Wu and Howe, 1995)
Class of aberration (relative to progenitor)	chromosomal_deletion (Wu et al., 1989, Wu and Howe, 1995)
Breakpoints	49D2-49E2;49E2-49F2 (Wu and Howe, 1995) 49D2--E2;[] (Wu et al., 1989)
Causes alleles	Su(z)2⁵ (Wu and Howe, 1995, Wu et al., 1989)
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 hits vg << bk2 hits Su(z)2
Genetic mapping information
Comments	Deficiency breakpoint maps within exon 4 of vg. (Williams et al., 1990)
Comments on Cytology
	Ref: FBrf0041631. (Wu and Howe, 1995) Left limit of break 1 from polytene analysis (FBrf0050577) Right limit of break 1 from inclusion of vg (FBrf0051982) Left limit of break 2 from inclusion of Su(z)2 (FBrf0082794) Right limit of break 2 from polytene analysis (FBrf0082794)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	l(2)49Dc (Wu and Howe, 1995) Mdr49 (Wu and Howe, 1995) Psc (Muller et al., 1999, Wu and Howe, 1995) Su(z)2 (Muller et al., 1999, Wu and Howe, 1995) vg (Williams et al., 1990, Williams et al., 1990)
Partially deleted / disrupted	Su(z)2 (Wu and Howe, 1995) vg (Wu and Howe, 1995)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Cap-G (Wu and Howe, 1995) l(2)49Fa (Wu and Howe, 1995) l(2)49Fb (Wu and Howe, 1995) l(2)49Fg (Wu and Howe, 1995) l(2)49Fh (Wu and Howe, 1995) lat (Wu and Howe, 1995) seq (Wu and Howe, 1995)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Can show a strong dominant suppression on telomeric Position Effect Variegation (PEV) in stocks carrying a variegating w^+mW.hs allele at the telomeres of the second and third chromosomes. Has no effect on pericentric and fourth chromosome insertions. (Cryderman et al., 1999) Intermediate vg phenotype. (Williams et al., 1990)
Stocks ( 0 )

Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	Second breakpoint not reported. (Wu et al., 1989)
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	Df(2R)Psc^Suz2-5 Df(2R)Su(z)2-5 (Wu et al., 1989) Df(2R)Su(z)2⁵ Su(z)2-5 (Bajusz et al., 2001) Su(z)2⁵ (Mason et al., 2000, Cryderman et al., 1999, Williams et al., 1990, Rastelli et al., 1993)
Name Synonym
Secondary FlyBase IDs

References ( 11 )
Research paper	Bajusz et al., 2001, Genetics 159(3): 1135--1150 The Trithorax-mimic allele of Enhancer of zeste renders active domains of target genes accessible to polycomb-group-dependent silencing in Drosophila melanogaster. [FBrf0141551] Mason et al., 2000, Genetica 109(1-2): 61--70 Control of telomere elongation and telomeric silencing in Drosophila melanogaster. [FBrf0135797] Cryderman et al., 1999, EMBO J. 18(13): 3724--3735 Silencing at Drosophila telomeres: nuclear organization and chromatin structure play critical roles. [FBrf0109548] Muller et al., 1999, Genetics 153(3): 1333--1356 The mcp element from the Drosophila melanogaster bithorax complex mediates long-distance regulatory interactions. [FBrf0111986] Wu and Howe, 1995, Genetics 140(1): 139--181 A genetic analysis of the suppressor 2 of zeste complex of Drosophila melanogaster. [FBrf0082794] Rastelli et al., 1993, EMBO J. 12(4): 1513--1522 Related chromosome binding sites for zeste, suppressors of zeste and Polycomb group proteins in Drosophila and their dependence on Enhancer of zeste function. [FBrf0058142] Williams et al., 1990, Genetics 125: 833--844 Genetic and molecular analysis of vg^U and vg^W: two dominant vg alleles associated with gene fusions in Drosophila. [FBrf0051982] Williams et al., 1990, Mol. Gen. Genet. 221(1): 8--16 The functional organization of the vestigial locus in Drosophila melanogaster. [FBrf0052606] Wu et al., 1989, Mol. Gen. Genet. 218: 559--564 Homeosis and the interaction of zeste and white in Drosophila. [FBrf0050577] Williams and Bell, 1988, EMBO J. 7: 1355--1363 Molecular organization of the vestigial region in Drosophila melanogaster. [FBrf0047923]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]

Aberration Dmel\Df(2R)Su(z)25

Aberration Dmel\Df(2R)Su(z)2⁵