Aberration Dmel\Df(2R)WMG

General Information
Symbol	Dmel\Df(2R)WMG	Species	D. melanogaster
Name		FlyBase ID	FBab0002046
Feature type	chromosomal_deletion
Also Known As	Df(2R)WMG268.12

Computed Breakpoints include	52A9-52A10;52D9-52D15
Deleted segment	52A9--52D15
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion (Bopp et al., 1989, Rabinow et al., 1991, Davis and MacIntyre, 1988, Pauli et al., 1995, Duffy et al., 1996, Chase and Kankel, 1987, Hellmich et al., 1994, Harbecke and Lengyel, 1995, Awasaki and Kimura, 1997, Schupbach and Wieschaus, 1989)
Breakpoints	52A2-52B4;52D7-52E1 (Hellmich et al., 1994) 52A4-52B2;52D7-52E1 (Davis and MacIntyre, 1988) 52A4-52B12;52D9-52D15 (Chase and Kankel, 1987) 52A9-52A10;52D12-52D15 (Rabinow et al., 1991) 52A;52D (Schupbach and Wieschaus, 1989, Pauli et al., 1995, Harbecke and Lengyel, 1995, Duffy et al., 1996) 52C4;52E3 (Bopp et al., 1989, Awasaki and Kimura, 1997)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << l(2)52ACh << l(2)52Db << bk2 << Got1
Genetic mapping information
Comments
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0054158) Limits of break 2 from polytene analysis (FBrf0046776)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	c (Davis and MacIntyre, 1988) Cdk5 (Sauer et al., 1996) fus (Wakabayashi-Ito et al., 2001) Gpo-1 (Davis and MacIntyre, 1988) ifm(2)RS1 (Babu and Ramachandra, 2007) l(2)52ACa (Davis and MacIntyre, 1988) l(2)52ACb (Davis and MacIntyre, 1988) l(2)52ACc (Davis and MacIntyre, 1988) l(2)52ACd (Davis and MacIntyre, 1988) l(2)52ACe (Davis and MacIntyre, 1988) l(2)52ACf (Davis and MacIntyre, 1988) l(2)52ACg (Davis and MacIntyre, 1988) l(2)52ACh (Davis and MacIntyre, 1988) l(2)52Da (Davis and MacIntyre, 1988) l(2)52Db (Davis and MacIntyre, 1988) Poxn (Bopp et al., 1989, Dambly-Chaudiere et al., 1992, Awasaki and Kimura, 1997, Gautier et al., 1997) sli (Dambly-Chaudiere et al., 1992, Battye et al., 2001)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Got1 (Chase and Kankel, 1987) l(2)52Dc (Davis and MacIntyre, 1988) l(2)52Ea (Davis and MacIntyre, 1988) Prosβ1 (BDGP Project Members, 1994-1999) Rho1 (BDGP Project Members, 1994-1999) spin (BDGP Project Members, 1994-1999)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	The Df(2R)WMG chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Mutant embryos show complete fusion of the longitudinal and commissural nerve trunks - few intersegmental connections are maintained. (Battye et al., 2001) Acts as a dosage sensitive maternal modifier of run: causes tergite defects in greater than 50% of run³ heterozygotes. (Duffy et al., 1996) Homozygous embryos show defects in segmentation, germband retraction, dorsal closure and head involution. Elongation of Malpighian tubule material is variable. (Harbecke and Lengyel, 1995) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995)
Stocks ( 2 )
Bloomington	1887 Df(2R)WMG, wg^Sp-1 Bl¹ lt¹/In(2LR)Gla, wg^Gla-1
Kyoto	106557 Df(2R)WMG, wg^Sp-1 Bl¹ lt¹/In(2LR)Gla, wg^Gla-1
Notes on Origin
Discoverer	Gelbart.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Df(2R)WMG (Davis and MacIntyre, 1988, Keene et al., 2004, Babu and Ramachandra, 2007, Usui-Aoki et al., 2005) Df(2R)WMG268-18 Df(2R)WMG268.12 (Chase and Kankel, 1987, MacIntyre, 2007.8.30) Df(2R)WMG^268-18 (Davis and MacIntyre, 1988)
Name Synonym
Secondary FlyBase IDs
	FBab0002047
References ( 30 )

Generate a list of	All references relating to this aberration ( 30 )

List References by type	Research paper ( 25 ) Personal communication to FlyBase ( 2 ) Abstract ( 1 ) FlyBase analysis ( 1 ) Book ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...