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General Information
Symbol
Df(2R)X1
Species
D. melanogaster
Name
FlyBase ID
FBab0002048
Feature type
Computed Breakpoints include

46C2;47A1

Deleted Segment
Sequence coordinates
2R:9,922,003..9,927,457 [-] (Df(2R)X1:bk1)
2R:10,249,435..10,307,030 (Df(2R)X1:bk2)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 hits Mef2 << Syb << bk2

Genetic mapping information
Comments

The 2R:10249435..10307030 release 6 coordinates of the right breakpoint are estimates. The left extent corresponds to the left end of Syb, which published results say is deleted. The right extent corresponds to the left end of JhI-1, which published results say is not deleted.

This deletion removes multiple ribosomal protein-coding genes (in addition to other genes).

Comments on Cytology

Proximal breakpoint is 15-20kb distal to Fmrf.

Complementation data from unspecified deficiency chromosomes.

Left limit of break 1 from non-inclusion of Fmrf (FBrf0053296) Right limit of break 1 from inclusion of Mef2 (FBrf0078093) Limits of break 2 from polytene analysis (FBrf0058167)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Phenotypic Data
In combination with other aberrations

Lethal in combination with Df(2R)12.

NOT in combination with other aberrations

Flies heterozygous for the deletion do not show a Minute bristle phenotype.

The Df(2R)X1 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

Heterozygosity for Df(2R)X1 results in 2.0% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

Stocks (2)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

Complementation group identified in an EMS and DEB screen to isolate deficiencies that uncover Jra.

Synonyms and Secondary IDs (8)
References (60)