Aberration Dmel\Df(2R)b23

General Information
Symbol	Dmel\Df(2R)b23	Species	D. melanogaster
Name		FlyBase ID	FBab0002063
Feature type	chromosomal_deletion

Computed Breakpoints include	59F8;60A3
Deleted segment	59F8--60A3
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray (Gundacker et al., 1993)
Class of aberration (relative to progenitor)	chromosomal_deletion (Gundacker et al., 1993)
Breakpoints	59F8;60A3 (Gundacker et al., 1993)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	l(2)tid << bk1 << bgcn << bk2
Genetic mapping information
Comments
Comments on Cytology
	All limits from polytene analysis (FBrf0057980)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	bgcn (Munn and Steward, 2000, Ohlstein et al., 2000) gbb (Wharton et al., 1999) l(2)60A-F (Wharton et al., 1999) l(2)60Af (Wharton et al., 1999) l(2)60Ag (Wharton et al., 1999) l(2)60Ai (Wharton et al., 1999) l(2)60A-K (Wharton et al., 1999) l(2)60A-L (Wharton et al., 1999) l(2)60A-M (Wharton et al., 1999) l(2)60A-N (Wharton et al., 1999) l(2)60A-O (Wharton et al., 1999) shu (Munn and Steward, 2000) ytr (Sinenko et al., 2004)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	kcc (Wharton et al., 1999, Hekmat-Scafe et al., 2006) l(2)60A-A (Wharton et al., 1999) l(2)60A-B (Wharton et al., 1999) l(2)60A-D (Wharton et al., 1999) l(2)60A-E (Wharton et al., 1999) l(2)60A-H (Wharton et al., 1999) l(2)60Ah (Wharton et al., 1999) l(2)60A-I (Wharton et al., 1999) l(2)tid (Gundacker et al., 1993) l(2)vsp (Wharton et al., 1999)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Stocks ( 0 )

Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(2R)b23 (Hekmat-Scafe et al., 2006)
Name Synonym
Secondary FlyBase IDs

References ( 11 )
Research paper	Hekmat-Scafe et al., 2006, J. Neurosci. 26(35): 8943--8954 Mutations in the K+/Cl- cotransporter gene kazachoc (kcc) increase seizure susceptibility in Drosophila. [FBrf0192588] Sinenko et al., 2004, Dev. Biol. 273(1): 48--62 Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. [FBrf0179728] Munn and Steward, 2000, Genetics 156(1): 245--256 The shut-down gene of Drosophila melanogaster encodes a novel FK506-binding protein essential for the formation of germline cysts during oogenesis. [FBrf0129984] Ohlstein et al., 2000, Genetics 155(4): 1809--1819 The Drosophila cystoblast differentiation factor, benign gonial cell neoplasm, is related to DExH-box proteins and interacts genetically with bag-of-marbles. [FBrf0130002] Lavoie et al., 1999, Dev. Biol. 212(2): 405--413 Localization and function of bam protein require the benign gonial cell neoplasm gene product. [FBrf0110155] Wharton et al., 1999, Genetics 152(2): 629--640 Genetic analysis of the bone morphogenetic protein-related gene, gbb, identifies multiple requirements during Drosophila development. [FBrf0109147] Gundacker et al., 1993, D. I. S. 72: 129 Genetic and molecular characterization of breakpoints of five deficiencies in the genomic region 59F-60A. [FBrf0057980] Kurzik-Dumke et al., 1992, Differentiation 51(2): 91--104 Genetic, cytogenetic and developmental analysis of the Drosophila melanogaster tumor suppressor gene lethal(2)tumorous imaginal discs (l(2)tid). [FBrf0055923] Loffler et al., 1990, Environ. Hlth Perspect. 88: 157--161 Genetic and molecular analysis of six tumor suppressor genes in Drosophila melanogaster. [FBrf0051687]
Review	Gateff and Mechler, 1989, Crit. Rev. Oncogen. 1: 221--245 Tumor-suppressor genes of Drosophila melanogaster. [FBrf0049455]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]