Open Close
General Information
Symbol
Df(2R)bw5
Species
D. melanogaster
Name
Deficiency (2R) brown
FlyBase ID
FBab0002071
Feature type
Also Known As
Df(2R)bw5
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << bw << egl << bk2

Genetic mapping information
Comments
Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0048677) Right limit of break 1 from polytene analysis (FBrf0080317) Left limit of break 2 from inclusion of egl (FBrf0083926)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    No effect on In(1)wm4h position-effect variegation.

    NOT in combination with other aberrations

    Homozygotes have electrophysiological defects, head defects and the ventral nerve cord fails to contract.

    Heterozygotes with Byron exhibit about 2% eye pigmentation.

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    Stocks (3)
    Notes on Origin
    Discoverer

    Mohr, 28th Nov. 1931.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2R)bw5 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(2R)bw5 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing.

    Synonyms and Secondary IDs (3)
    References (28)