FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2R)cn9
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General Information
Symbol
Df(2R)cn9
Species
D. melanogaster
Name
Deficiency (2R) cinnabar
FlyBase ID
FBab0002170
Feature type
chromosomal_deletion
Computed Breakpoints include

42E;44C1

Features within 42E--44C1
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
MRF23.5 induced male recombination
male recombination induced by dysgenesis
(Yannopoulos et al., 1981)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Duffy et al., 1996, Zhang et al., 1996, Harbecke and Lengyel, 1995, Kania et al., 1995, Pauli et al., 1995, Yannopoulos et al., 1981)
Breakpoints

42E;44C

(Duffy et al., 1996, Zhang et al., 1996, Harbecke and Lengyel, 1995, Kania et al., 1995, Pauli et al., 1995, Yannopoulos et al., 1981)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

Eb1 << bk1 << so << sax << bk2 << pnut

Genetic mapping information
Comments
Comments on Cytology

Ref: Lindsley and Zimm, 1992

(Kania et al., 1995)

Limits of break 1 from polytene analysis (FBrf0037137) Left limit of break 2 from polytene analysis (FBrf0037137) Right limit of break 2 from non-inclusion of pnut (FBrf0067338)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
l(2)08492
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
Rpt1
(Spradling et al., 1999, BDGP Project Members, 1994-1999)
sax
(Nellen et al., 1994)
so
(Yannopoulos et al., 1981)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Heterozygosity for Df(2R)cn9 results in 1.3% X chromosome nondisjunction and 0.9% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

    (Harris et al., 2003)

    No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

    (Halsell and Kiehart, 1998)

    Shows no maternal enhancement of dpphr4.

    (Nicholls and Gelbart, 1998)

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    (Duffy et al., 1996)

    Heterozygotes with Df(2R)44CE exhibit aberrant migration of the germ cell.

    (Zhang et al., 1996)

    Deficient embryos show an uninterpretable mutant midgut phenotype.

    (Bilder and Scott, 1995)

    Homozygous embryos show abnormal dorsal closure and tracheae are abnormal.

    (Harbecke and Lengyel, 1995)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)
    Stocks (1)
    Notes on Origin
    Discoverer
     

    The stock contains a second-site deletion uncovering l(2)gl.

    (Roegiers et al., 2009)

    Associated with: wunCN.

    (Zhang et al., 1996)

    Recovered as apparent cn double recombinants from test crosses of dysgenic-type males that were heterozygous for a maternally derived dp b cn bw second chromosome and paternally derived autosomes extracted from natural populations and capable of promoting male recombination.

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2R)cn9 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies.

    (Mason et al., 2004)
    Synonyms and Secondary IDs (5)
    References (47)