FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2R)eve
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General Information
Symbol
Df(2R)eve
Species
D. melanogaster
Name
Deficiency (2R) even-skipped
FlyBase ID
FBab0002177
Feature type
chromosomal_deletion
Also Known As
Df(2R)eve1.27, Df(2R)eve1.27, eve1.27
Computed Breakpoints include

46C3-46C4;46C9-46C11

Features within 46C3--46C11
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Duffy et al., 1996, Harbecke and Lengyel, 1995, Kania et al., 1995, Pauli et al., 1995, Landecker et al., 1994, Schupbach and Wieschaus, 1991)
Breakpoints

46C3-46C4;46C9-46C11

(Duffy et al., 1996, Harbecke and Lengyel, 1995, Kania et al., 1995, Pauli et al., 1995, Landecker et al., 1994, Schupbach and Wieschaus, 1991)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

Mef2 << bk1 << l(2)46Cp << l(2)46Cd << bk2 << TER94

Genetic mapping information
Comments
Comments on Cytology

Ref: Lindsley and Zimm, 1992

(Kania et al., 1995)

Ref: Nusslein-Volhard et al., 1985, Cold Spring Harbor Symp. Quant. Biol. 50: 145--154. Proximal breakpoint is 40-45kb distal to Fmrf.

(O'Brien et al., 1994)

All limits from polytene analysis (FBrf0054123)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Complementation Data
 
14-3-3ζ
(Goldstein et al., 2001)
Etf-QO
(O'Brien et al., 1994)
FMRFa
(O'Brien et al., 1994, Nambu et al., 1988)
Hr3
(Goldstein et al., 2001)
Jra
(Goldstein et al., 2001)
l(2)46Cb
(O'Brien et al., 1994)
l(2)46CFn
(Goldstein et al., 2001)
l(2)46Ci
(Goldstein et al., 2001)
l(2)46Cj
(Goldstein et al., 2001)
l(2)46Ck
(Goldstein et al., 2001)
l(2)46Cl
(Goldstein et al., 2001)
l(2)46Cm
(Goldstein et al., 2001)
l(2)46Cn
(Goldstein et al., 2001)
l(2)46Da
(O'Brien et al., 1994)
l(2)46Dc
(O'Brien et al., 1994)
l(2)46Dd
(O'Brien et al., 1994)
l(2)46De
(O'Brien et al., 1994)
l(2)46DEa
(Ranganayakulu et al., 1995)
l(2)46DEb
(Ranganayakulu et al., 1995)
l(2)46DEc
(Ranganayakulu et al., 1995)
l(2)46DEd
(Ranganayakulu et al., 1995)
l(2)46Df
(O'Brien et al., 1994)
l(2)46Dg
(O'Brien et al., 1994)
l(2)46Dh
(Goldstein et al., 2001)
l(2)46Di
(Goldstein et al., 2001)
l(2)46Dj
(Goldstein et al., 2001)
l(2)46Ea
(Goldstein et al., 2001)
l(2)46Eb
(Goldstein et al., 2001)
l(2)46Ec
(Goldstein et al., 2001)
l(2)46Ed
(Goldstein et al., 2001)
l(2)46Eg
(Goldstein et al., 2001)
l(2)46Eh
(Goldstein et al., 2001)
l(2)46Ei
(Goldstein et al., 2001)
l(2)46Ej
(Goldstein et al., 2001)
l(2)46Fa
(Goldstein et al., 2001)
l(2)46Fb
(Goldstein et al., 2001)
l(2)gl
(Mason et al., 2004)
l(2)k05422a
(Kania et al., 1995, BDGP Project Members, 1994-1999)
l(2)k06408
(BDGP Project Members, 1994-1999)
l(2)k07803
(BDGP Project Members, 1994-1999)
Mef2
(Goldstein et al., 2001, Schulz et al., 1996, Lilly et al., 1995, Ranganayakulu et al., 1995)
Syb
(Goldstein et al., 2001)
TER94
(Goldstein et al., 2001, BDGP Project Members, 1994-1999, O'Brien et al., 1994)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    No effect on In(1)wm4h position-effect variegation.

    (Wustmann et al., 1989)
    NOT in combination with other aberrations

    Mutant animals exhibit defects in axonal projections

    (Fujioka et al., 2003)

    Shows no maternal enhancement of dpphr4.

    (Nicholls and Gelbart, 1998)

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    (Duffy et al., 1996)

    Deficient embryos show an uninterpretable mutant midgut phenotype.

    (Bilder and Scott, 1995)

    Homozygous embryos do not complete head involution, tracheae are disconnected and salivary glands are bulgy. Formation and maintenance of the midgut epithelium is variable, and midgut constrictions do not form.

    (Harbecke and Lengyel, 1995)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    Reduced ventral cord.

    (Smith et al., 1993)
    Stocks (3)
    Notes on Origin
    Discoverer

    Nusslein-Volhard.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2R)eve chromosome acts as a dominant moderate suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies. The suppressor maps to the tip of 2L rather than to the site of the deficiency.

    (Mason et al., 2004)
    Synonyms and Secondary IDs (11)
    References (76)