FlyBase Aberration Report: Dmel\Df(2R)pk78s

General Information

Symbol

Df(2R)pk78s

Species

D. melanogaster

Name

Inversion (2R) prickle

FlyBase ID

FBab0002198

Feature type

deficient_inversion

Also Known As

Df(2R)pk^78s, In(2R)pk78s

Computed Breakpoints include

42C7;43F8;59F5-59F8

Features within 42C7--43F8

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

(Ashburner et al., 1981)

Class of aberration (relative to wild type)

deficient_inversion

Class of aberration (relative to progenitor)

deficient_inversion

(Beaton, 1997.3.4, Nellen et al., 1994, Ashburner et al., 1981)

chromosomal_deletion

(Chandrashekaran and Sarla, 1993)

Breakpoints

42C1-42C7;43F5-43F8;59F5-59F8

(Ashburner et al., 1981)

42C1-42C7;43F5-43F8

(Harbecke and Lengyel, 1995, Pauli et al., 1995, Castrillon et al., 1993, Grau and Simpson, 1987)

42C1-42C7;43F8-43F9

(Chandrashekaran and Sarla, 1993)

43C1--43C7;43F5--8;[]

(Nellen et al., 1994)

42C7;43F5-43F8;2ce-2Rt

(Beaton, 1997.3.4)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

l(2)01289 << bk1 << nec << sax << bk2

Genetic mapping information

Comments

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0092781) Right limit of break 1 from polytene analysis (FBrf0036112) Left limit of break 2 from polytene analysis (FBrf0065355) Right limit of break 2 from polytene analysis (FBrf0036112) Limits of break 3 from polytene analysis (FBrf0036112)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Aldh-III

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

(Ashburner et al., 1981)

cos

(BDGP Project Members, 1994-1999, Grau and Simpson, 1987)

crib

(Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989)

Cyt-b5

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Dscam1

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

fs(2)ltoRN73

(Schupbach and Wieschaus, 1991)

l(2)43Bb

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(2)08492

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

mat(2)cell-J

(Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989)

ms(2)42D

(Castrillon et al., 1993)

Orc1

(Schupbach and Wieschaus, 1991)

(Ashburner et al., 1981)

pwn

(Ashburner et al., 1981)

Rpt1

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

sax

(Bilder and Scott, 1995, Nellen et al., 1994, Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989)

scra

(Spradling et al., 1999, BDGP Project Members, 1994-1999, Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989)

tor

(Schupbach and Wieschaus, 1991, Schupbach and Wieschaus, 1989, Schupbach and Wieschaus, 1986)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
In these cases, there will be no "Export to Hitlist" button to the left.

Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

The Df(2R)pk78s chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(2R)pk78s results in 1.1% X chromosome nondisjunction and 0.6% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females.

(Harris et al., 2003)

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpp^hr4.

(Nicholls and Gelbart, 1998)

Dominantly suppresses the wing basal cell 1 swirl phenotype of Vang alleles.

(Taylor et al., 1998)

Deficient embryos show a mutant midgut phenotype: central constriction is absent.

(Bilder and Scott, 1995)

Homozygous embryos have fewer segments than normal and the tracheae are abnormal. The midgut does not constrict and Malpighian tubules are not fully elongated.

(Harbecke and Lengyel, 1995)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Large ventral cord cells.

(Smith et al., 1993)

Stocks (2)

1930

106584

Notes on Origin

Discoverer

D. Gubb.

(Ashburner et al., 1981)

Gubb.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

"42C7;43F5--8;2cen--2Rt" was stated as revision.

(Beaton, 1997.3.4)

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

Df(2R)pk78S

(LaJeunesse et al., 2001)

Df(2R)pk^78s

(Crest et al., 2007, Abrell et al., 2000, Taylor et al., 1998, Grau and Simpson, 1987, Ashburner et al., 1981)

In(2R)pk78s

(Cole et al., 2005, Brumby et al., 2004)

In(2R)pk⁷⁸

In(2R)pk^78s

(Ashburner et al., 1981)

Name Synonyms

Inversion (2R) prickle

Secondary FlyBase IDs

FBab0005134

References (39)

Report Sections

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