FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(2R)vg-D
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General Information
Symbol
Df(2R)vg-D
Species
D. melanogaster
Name
Deficiency (2R) vestigial-Depilate
FlyBase ID
FBab0002235
Feature type
chromosomal_deletion
Also Known As
Df(2R)vgD, Df(2R)vgD, vgD
Computed Breakpoints include

49C1-49C2;49E6

Features within 49C1--49E6
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
spontaneous
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Pennetta and Pauli, 1997, Price et al., 1997, Zars and Hyde, 1996, Pauli et al., 1995, Wu and Howe, 1995, Brunk and Adler, 1990, Rabinow and Birchler, 1990, Bownes and Roberts, 1981)
Breakpoints

49C1-49C2;49E2-49E6

(Pennetta and Pauli, 1997, Pauli et al., 1995, Brunk and Adler, 1990, Schupbach and Wieschaus, 1989, Bownes and Roberts, 1981)

49C;49E

(Rabinow and Birchler, 1990)

49D3-49D4;50A2-50A3

(Rabinow et al., 1991)

49C1-49D1;49E2-49F2

(Zars and Hyde, 1996, Wu and Howe, 1995)

49C1-49C2;49E4-49E5

(Price et al., 1997)
Causes alleles
Su(z)2vgD
(Wu and Howe, 1995, Brunk et al., 1991, Adler et al., 1989)
PscvgD
(Lopez et al., 2001, Simon et al., 1992)
Carries alleles
Transposon Insertions
Formalized genetic data

rdgE << bk1 << E(Egfr)B56 << Su(z)2 << bk2 << Psc

Genetic mapping information
Comments

Breakpoint(s) molecularly mapped

(Brunk and Adler, 1990)
Comments on Cytology

Ref: FBrf0050577.

(Wu and Howe, 1995)

Limits of break 1 from polytene analysis (FBrf0036848) Left limit of break 2 from inclusion of Su(z)2 (FBrf0049524) Right limit of break 2 from polytene analysis (FBrf0036848)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Df(2R)Exel8056/Df(2R)vg-D transheterozygosity is lethal.

    (Ahmad and Spens, 2019)

    Lethal in combination with Df(2R)Su(z)25.

    (Wu and Howe, 1995)
    NOT in combination with other aberrations

    Df(2R)vg-D homozygosity is lethal.

    (Ahmad and Spens, 2019)

    The Df(2R)vg-D chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    (Mason et al., 2004)

    Has no effect on the phenotype of dominant ovo alleles.

    (Pennetta and Pauli, 1997)

    Complementation tests with E(Egfr)B56B56 reveal defects in wing vein L2, L4 and L5.

    (Price et al., 1997)

    Heterozygotes with rdgE1 exhibit presense of a deep pseudopupil after 7 days in constant light.

    (Zars and Hyde, 1996)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    Strong notum bristle loss phenotype. Phenotype enhanced after heat shock when in combination with Su(z)2hs.PS.

    (Sharp et al., 1994)

    Macrochaetae on the dorsal thorax are lost or reduced in size, a loss or duplication of bristles on the femur and tibia and a reduction in the number of frontal and postorbital bristles on the head is evident.

    (Brunk et al., 1991)

    Greatly enhances dorsal dominant phenotype of dl mutant embryos.

    (Steward and Nusslein-Volhard, 1986)

    Heterozygotes have sparse hairs and bristles on the thorax.

    (Bownes and Roberts, 1981)

    Enhances BicD in heterozygotes (Mohler and Wieschaus, 1986, Genetics 112: 803-22) Df(2R)vgD/+ flies show dominant flightlessness (Cripps and Sparrow, 1989, Dev. Genet. 10: 98-105) and loss of bristles on legs and anterior dorsal thorax (Morgan, et al., 1938) homozygous lethal

    Stocks (3)
    Notes on Origin
    Discoverer

    Bridges, 22 Jan. 1931.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Removes most of the Psc transcription unit.

    (Simon et al., 1992)

    Deletion ends within 20kb proximal to the distal break of In(2R)Arp1.

    (Brunk et al., 1991)
    Synonyms and Secondary IDs (8)
    References (44)