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General Information
D. melanogaster
Deficiency (2R) vestigial
FlyBase ID
Feature type
Also Known As
Computed Breakpoints include


Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Class of aberration (relative to wild type)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

Cam << bk1 << Gα49B << bk2 << Psc << nompA << bk3 << l(2)k06407

Genetic mapping information

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

Breakpoint(s) molecularly mapped

Comments on Cytology

Ref: Lindsley and Zimm, 1992

Left limit of break 1 from polytene analysis (FBrf0055685) Right limit of break 1 from polytene analysis (FBrf0082455) Right limit of break 2 from non-inclusion of Psc (FBrf0048224) Left limit of break 3 from polytene analysis (FBrf0055685)

Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
Molecular Data
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Flies heterozygous for the deletion do not show a Minute bristle phenotype.

    Heterozygosity for Df(2R)vg135 results in 2.7% X chromosome nondisjunction and 1.9% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

    Heterozygous adults show fusion of the β lobes in the central brain with intermediate penetrance.

    No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.

    Shows no maternal enhancement of dpphr4.

    Enhances the phenotype of dominant ovo alleles.

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    Homozygous lethal. Heterozygotes with rdgE1 exhibit absence of a deep pseudopupil after 7 days in constant light.

    Deficient embryos show a variably penetrant mutant midgut phenotype: incomplete constriction formation.

    Homozygous embryos show abnormal head epithelium differentiation.

    Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovoD2.

    Homozygous lethal.

    Does not exhibit dominant flightlessness.

    homozygous lethal

    Stocks (3)
    Notes on Origin

    Associated with: nompAvg135.

    Balancer / Genotype Variants of the Aberration
    Separable Components
    Other Comments

    The Df(2R)vg135 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(2L)Prl overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing. In addition, the deficiency chromosome fails to complement lethal mutations of l(2)gl.

    "49B2--7;49E2--F1;47F16--18" was stated as revision.

    Synonyms and Secondary IDs (7)
    References (60)