Open Close
General Information
Symbol
Df(2R)vg135
Species
D. melanogaster
Name
Deficiency (2R) vestigial
FlyBase ID
FBab0002246
Feature type
Also Known As
Df(2R)vg135
Computed Breakpoints include
49A;49E1-49E2;47F4-47F18
Deleted Segment
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Cam << bk1 << Gα49B << bk2 << Psc << nompA << bk3 << l(2)k06407
Genetic mapping information
Comments
This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).
Breakpoint(s) molecularly mapped
Comments on Cytology
Ref: Lindsley and Zimm, 1992
Left limit of break 1 from polytene analysis (FBrf0055685) Right limit of break 1 from polytene analysis (FBrf0082455) Right limit of break 2 from non-inclusion of Psc (FBrf0048224) Left limit of break 3 from polytene analysis (FBrf0055685)
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Flies heterozygous for the deletion do not show a Minute bristle phenotype.
Heterozygosity for Df(2R)vg135 results in 2.7% X chromosome nondisjunction and 1.9% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.
Heterozygous adults show fusion of the β lobes in the central brain with intermediate penetrance.
No second site non-complementing phenotype with zipEbr and zipmhc-c6.1.
Shows no maternal enhancement of dpphr4.
Enhances the phenotype of dominant ovo alleles.
Dominantly causes tergite defects in less than 50% of run3 heterozygotes.
Homozygous lethal. Heterozygotes with rdgE1 exhibit absence of a deep pseudopupil after 7 days in constant light.
Deficient embryos show a variably penetrant mutant midgut phenotype: incomplete constriction formation.
Homozygous embryos show abnormal head epithelium differentiation.
Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovoD2.
Homozygous lethal.
Does not exhibit dominant flightlessness.
homozygous lethal
Stocks (3)
Notes on Origin
Discoverer
 
Associated with: nompAvg135.
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
The Df(2R)vg135 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(2L)Prl overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing. In addition, the deficiency chromosome fails to complement lethal mutations of l(2)gl.
"49B2--7;49E2--F1;47F16--18" was stated as revision.
Synonyms and Secondary IDs (7)
Reported As
Name Synonyms
Deficiency (2R) vestigial
Secondary FlyBase IDs
  • FBab0024398
References (57)