FlyBase Aberration Report: Dmel\Df(3L)1-166

General Information

Symbol

Df(3L)1-166

Species

D. melanogaster

Name

FlyBase ID

FBab0002281

Feature type

chromosomal_deletion

Also Known As

1-166

Computed Breakpoints include

80F;80F

Features within 80F--80F

Genomic Maps

JBrowse

Sequence coordinates

3L:25,762,779..26,014,112 (Df(3L)1-166:bk1)

(Cook, 2019.5.6)

3L:27,967,244..28,112,227 (Df(3L)1-166:bk2)

(Cook, 2019.5.6)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

C(3R)RM*

C(3L)RM*

Mutagen

detachment

ethyl methanesulfonate

(Marchant and Holm, 1988)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Schulze et al., 2001, Marchant and Holm, 1988)

Breakpoints

[];[]

(Schulze et al., 2001, Marchant and Holm, 1988)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

l(3)80Ff << bk1 << l(3)80Fg << l(3)80Fj << bk2 << l(3)81Fa

Genetic mapping information

Comments

The 3L:25762779..26014112 release 6 coordinates of the left breakpoint are estimates. The left extent corresponds to the right end of FASN3, which Syrzycka et al. (FBrf0242319) say is not deleted. The right extent corresponds to the right end of CG40178, which Syrzycka et al. (FBrf0242319) say is deleted.

(Cook, 2019.5.6)

The 3L:27967244..28112227 release 6 coordinates of the right breakpoint are estimates. The left extent corresponds to the left end of CG17514, which Syrzycka et al. (FBrf0242319) say is deleted. Because Df(3L)1-166 extends into centric heterochromatin according to Syrzycka et al. (FBrf0242319), the right extent is shown arbitrarily as the right end of chromosome 4 genome assembly.

(Cook, 2019.5.6)

Comments on Cytology

Left limit of break 1 from non-inclusion of l(3)80Ff (FBrf0048227) Right limit of break 1 from inclusion of l(3)80Fg (FBrf0048227) Left limit of break 2 from inclusion of l(3)80Fg (FBrf0048227) Right limit of break 2 from polytene analysis (citation unavailable)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Partially deleted / disrupted

Molecular Data

Completely deleted

eIF4B

(Syrzycka et al., 2019)

l(3)80Fj

(Syrzycka et al., 2019)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

FASN3

(Schulze et al., 2001, Marchant and Holm, 1988)

l(3)80Fd

(Schulze et al., 2001)

l(3)81Fa

(Marchant and Holm, 1988)

mRpS5

(Schulze et al., 2001)

nvd

(Schulze et al., 2001)

scro

(Schulze et al., 2001)

Molecular Data

ND-AGGG

(Syrzycka et al., 2019)

scro

(Syrzycka et al., 2019)

Set1

(Syrzycka et al., 2019)

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (22)

Related Comments

Phenotypic Data

In combination with other aberrations

Inferred to overlap with: Df(3L)9-56.

(Syrzycka et al., 2019)

Inferred to overlap with: In(3L)C90.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)AAA.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)Berry.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)JJJ.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)10A-301.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)2A-54.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)5A-406.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)7B-75.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)4A-1677.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)2-30.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)gamma-26.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)gamma-28.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)C-2.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)K-2.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)TTT.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)FX53.

(Syrzycka et al., 2019)

Inferred to overlap with: Df(3L)DDD.

(Syrzycka et al., 2019)

NOT in combination with other aberrations

The Df(3L)1-166 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Dominantly causes tergite defects in less than 50% of run³ heterozygotes.

(Duffy et al., 1996)

Stocks (2)

Bloomington

2590

Df(3L)1-166, kni^ri-1 p^p/TM3, ry^RK Sb¹ Ser¹

Kyoto

107415

Df(3L)1-166, kni^ri-1 p^p/TM3, Sb¹

Notes on Origin

Discoverer