Aberration Dmel\Df(3L)29A6

General Information
Symbol	Dmel\Df(3L)29A6	Species	D. melanogaster
Name		FlyBase ID	FBab0002286
Feature type	chromosomal_deletion	Created / Updated	2006-08-22/2006-08-22

Formalized genetic data	Argk << bk1 << bol << l(3)67Ab << bk2 << RpS17
Sequence coordinates
Deleted segment	66F5--67B1
Duplicated segment
Computed Breakpoints include	66F5;67B1
Breakpoints Inherited
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	diepoxybutane
Class of aberration (relative to progenitor)	chromosomal_deletion (Munneke and Collier, 1988, Smith et al., 1993, Pauli et al., 1995, Duffy et al., 1996, Hernandez et al., 1997, Harbecke and Lengyel, 1995, Deak et al., 1997)
Breakpoints	66F;67B (Munneke and Collier, 1988) 66F5;67B1 (Smith et al., 1993, Pauli et al., 1995, Harbecke and Lengyel, 1995, Duffy et al., 1996, Deak et al., 1997) 66F3;67B1 (Hernandez et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0065574) Right limit of break 1 from inclusion of Rdl (FBrf0054082) Limits of break 2 from polytene analysis (FBrf0065574)
Molecularly Mapped Breakpoints

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	eIF-4E (Hernandez et al., 1997, Deak et al., 1997, Szeged Stock Center, 1998-, Kankel et al., 2004, Hernandez et al., 2005) nwk (Coyle et al., 2004) Rdl (ffrench-Constant and Roush, 1991, ffrench-Constant et al., 1991, ffrench-Constant et al., 1992, ffrench-Constant, 1993, ffrench-Constant et al., 1993) bol (Castrillon et al., 1993) PGRP-LC (Wu et al., 2001) l(3)S036912 (Deak et al., 1997, Szeged Stock Center, 1998-) S(CycE^JP)3.4 (Brumby et al., 2004)
Molecular Data
Completely deleted	Tequila (Munier et al., 2004)
Genes NOT Deleted / Disrupted
Complementation Data
	fry (Cong et al., 2001) Shc (Luschnig et al., 2000) Argk (Munneke and Collier, 1988) Clk (Allada et al., 1998) vnc (Rees, 1990.8.1)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Df(3L)29A6/+ males are fertile and have no meiotic defects. (Gandhi et al., 2004) Deficient embryos show an uninterpretable mutant midgut phenotype. (Bilder and Scott, 1995) Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome. (Coyne et al., 1998) Dominantly causes tergite defects in less than 50% of run³ heterozygotes. (Duffy et al., 1996) Heterozygosity for this deletion suppresses the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) Homozygous embryos are very abnormal compared to wild-type. (Harbecke and Lengyel, 1995) No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1. (Halsell and Kiehart, 1998) Reduces the activity of the mitochondrial and cytoplasmic isozyme of Argk. (Munneke and Collier, 1988) Shows dominant enhancement of dominant haltere phenotype caused by Ubx¹⁹⁵ and Ubx^9.22. (Burnette et al., 1999) Shows no maternal enhancement of dpp^hr4. (Nicholls and Gelbart, 1998) The Df(3L)29A6 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3\'WP-2,w^var}2Lt insertion). (Mason et al., 2004)
Position Effect Variegation Data

Stocks ( 2 )
Bloomington	2479 Df(3L)29A6, kni^ri-1 p^p/TM3, Sb¹
Kyoto	107358 Df(3L)29A6, kni^ri-1 p^p/TM3, Sb¹
Notes on Origin
Discoverer
	isolated as lethal over Df(3L)AC1
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	29A6 (Yamaguchi et al., 2001, ffrench-Constant and Roush, 1991) Df29A6 (ffrench-Constant, 1993) Df(3L)29A (Frei et al., 2005) Df(3L)29A6 (Crest et al., 2007, Zaffran et al., 2006) l(3)67Ee
Name Synonym
Secondary FlyBase IDs

References ( 59 )

Generate a list of	All references relating to this aberration ( 59 )

List References by type	Research paper ( 53 ) Review ( 1 ) Personal communication to FlyBase ( 1 ) Abstract ( 1 ) FlyBase analysis ( 1 ) Computer file ( 1 ) Book ( 1 )
Recent research papers ( 2 )
	Crest et al., 2007, Genetics 175(2): 567--584 Onset of the DNA replication checkpoint in the early Drosophila embryo. [FBrf0194644] Zaffran et al., 2006, Development 133(20): 4073--4083 Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila. [FBrf0195151] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2006 Show reviews ...