FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(3L)Cat
Open Close
General Information
Symbol
Df(3L)Cat
Species
D. melanogaster
Name
Deficiency (3L) Catalase
FlyBase ID
FBab0002301
Feature type
chromosomal_deletion
Also Known As
Df(3L)CatDH104
Computed Breakpoints include

75C1-75C2;75F1

Features within 75B4--75E2 (Estimated cytology)
Genomic Maps
Sequence coordinates
3L:18,040,689..18,085,663 (Df(3L)Cat:bk1)
(Cook et al., 2010.2.12)
3L:18,840,455..18,841,891 (Df(3L)Cat:bk2)
(Cook et al., 2010.2.12)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
gamma ray
Class of aberration (relative to wild type)
chromosomal_deletion
(Cook et al., 2010.2.12, FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Deak et al., 1997, Salzberg et al., 1997, Duffy et al., 1996, Orr et al., 1996, Addison et al., 1995, Harbecke and Lengyel, 1995, Pauli et al., 1995, Smith et al., 1993, Mackay et al., 1986)
Breakpoints

75B8;75F1

(Duffy et al., 1996, Harbecke and Lengyel, 1995, Smith et al., 1993, Mackay et al., 1986)

75C1-75C2;75F1

(Deak et al., 1997, Salzberg et al., 1997, Orr et al., 1996, Pauli et al., 1995)

75B8-75B11;75F1

(Addison et al., 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

W << bk1 << not << l(3)03647 << bk2

Genetic mapping information
Comments
Comments on Cytology

The left Df(3L)Cat breakpoint lies within CG32192 or to its right in the range 3L:18033789..18078763 (R5) (predicted cytology: 75B4-75B7) based on the following evidence.

(Cook et al., 2010.2.12)

The right Df(3L)Cat breakpoint lies within Indy and perhaps within CG32027 in the range 3L:18833555..18834991 (R5) (predicted cytology: 75E2) based on the following evidence.

(Cook et al., 2010.2.12)

Left limit of break 1 from polytene analysis (FBrf0080317) Right limit of break 1 from inclusion of rpr (FBrf0074787) Limits of break 2 from polytene analysis (FBrf0044501)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
ads
(Addison et al., 1995)
bora
(Hutterer et al., 2006)
Capr
(Papoulas et al., 2010)
Cat
(Orr et al., 1996, Wheeler et al., 1995, Harshman et al., 1991)
E(ftz)2828
(Kankel et al., 2004)
ftz-f1
(Kankel et al., 2004, Broadus et al., 1999, Spradling et al., 1999)
hid
(Spradling, 1999.12.9)
l(3)00864
(Spradling et al., 1999)
l(3)03647
(Addison et al., 1995)
l(3)S000625a
(Szeged Stock Center, 1998-)
l(3)S004021
(Szeged Stock Center, 1998-)
l(3)S023825
(Szeged Stock Center, 1998-, Deak et al., 1997)
l(3)S023837b
(Deak et al., 1997)
l(3)S027614b
(Deak et al., 1997)
l(3)S041315b
(Deak et al., 1997)
l(3)S041316a
(Deak et al., 1997)
l(3)S042806b
(Deak et al., 1997)
l(3)S042834a
(Deak et al., 1997)
l(3)S043005a
(Deak et al., 1997)
l(3)S048301a
(Szeged Stock Center, 1998-, Deak et al., 1997)
l(3)S049413b
(Deak et al., 1997)
l(3)S051701b
(Deak et al., 1997)
l(3)S056003b
(Deak et al., 1997)
l(3)S059706a
(Deak et al., 1997)
l(3)S061207
(Szeged Stock Center, 1998-, Deak et al., 1997)
l(3)S073002a
(Szeged Stock Center, 1998-, Deak et al., 1997)
l(3)S088205
(Szeged Stock Center, 1998-)
l(3)S095109
(Szeged Stock Center, 1998-)
l(3)S116415
(Szeged Stock Center, 1998-, Deak et al., 1997)
l(3)S119607b
(Deak et al., 1997)
l(3)S122407b
(Deak et al., 1997)
l(3)S122413a
(Deak et al., 1997)
l(3)S132214
(Deak et al., 1997)
l(3)S132312
(Deak et al., 1997)
l(3)S144607b
(Szeged Stock Center, 1998-)
l(3)S146604b
(Deak et al., 1997)
l(3)S146901
(Deak et al., 1997)
l(3)S147402
(Deak et al., 1997)
l(3)S147406a
(Deak et al., 1997)
l(3)S147410
(Deak et al., 1997)
not
(Addison et al., 1995, Martin et al., 1995)
ripp
(Giesen et al., 2003)
rpr
(White et al., 1994)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (96)
Phenotypic Data
In combination with other aberrations

Fails to complement Df(3L)Δ26, Df(3L)Δ32, Df(3L)Δ54, Df(3L)Δ215 and Df(3L)Δ3002. Lethal in combination with Df(3L)GR844X22, Df(3L)GR844X31 or Df(3L)GR844X33.

(Addison et al., 1995)
NOT in combination with other aberrations

The wing discs of Df(3L)Cat/+ mutant third instar larvae exhibit reduced levels of apoptosis in response to X-ray induced irradiation with 4000 rads compared to controls.

(Brodsky et al., 2004)

The Df(3L)Cat chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(3L)Cat results in 14.5% X chromosome nondisjunction and 2.1% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

(Harris et al., 2003)

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

Weak second site non-complementing phenotype with zipEbr and zipmhc-c6.1 : malformed phenotype penetrance 10-24%.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpphr4.

(Nicholls and Gelbart, 1998)

Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

(Duffy et al., 1996)

Midgut development of mutant embryos is wild type.

(Bilder and Scott, 1995)

Homozygous embryos do not complete head involution, tracheae are disrupted, salivary glands are abnormal and there are holes in the epidermis. Midgut constrictions are incomplete and Malpighian tubules have a variable diameter along their length.

(Harbecke and Lengyel, 1995)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

(Pauli et al., 1995)

Homozygotes show the full cell death defective phenotype.

(White et al., 1994)

Replication defective.

(Smith et al., 1993)

Recessive lethal. Exhibits gene dosage effect for catalase activity as a heterozygote.

(Mackay and Bewley, 1989)

Exerts a dosage effect for Cat activity.

(Mackay et al., 1986)

Deficiency heterozygotes show dosage effect for catalase activity.

Stocks (2)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (13)
References (70)