FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(3L)GN24
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General Information
Symbol
Df(3L)GN24
Species
D. melanogaster
Name
FlyBase ID
FBab0002318
Feature type
chromosomal_deletion
Computed Breakpoints include

63F6-63F7;64C13-64C15

Features within 63F6--64C9 (Estimated cytology)
Genomic Maps
Sequence coordinates
3L:3,910,034..3,935,268 (Df(3L)GN24:bk1)
(Cook et al., 2010.2.12)
3L:5,184,785..5,235,796 (Df(3L)GN24:bk2)
(Cook et al., 2010.2.12)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
chromosomal_deletion
(Cook et al., 2010.2.12, FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Boube et al., 1997, Gepner et al., 1996, Rawson, 1992)
Breakpoints

63F4-63F7;64C13-64C15

(Boube et al., 1997, Gepner et al., 1996, Rawson, 1992)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

Sc2 << bk1 << l(3)rG166 << Srp54k << bk2 << sinu

Genetic mapping information
Comments

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

(Marygold et al., 2007)
Comments on Cytology

The left Df(3L)GN24 breakpoint lies within Eip63F-1 or Eip63F-2 or in the region between them, and lies in the range 3L:3910034..3935268 (R5) (predicted cytology: 63F6-63F7).

(Cook et al., 2010.2.12)

The right Df(3L)GN24 breakpoint lies within shep and perhaps also within the intronic gene CG4669 in the range 3L:5177885..5228896 (R5) (predicted cytology: 64C8-64C9).

(Cook et al., 2010.2.12)

Left limit of break 1 from non-inclusion of Sc2 (FBrf0067338) Right limit of break 1 from polytene analysis (FBrf0075338) Limits of break 2 from polytene analysis (FBrf0075338)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (193)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations

Flies heterozygous for the deletion do not show a Minute bristle phenotype.

(Marygold et al., 2007)

Heterozygotes are moderately sensitive to ionising radiation compared to control flies.

(Holmes et al., 2006)

Df(3L)GN24 embryos show defects in tracheal cell migration within specific metameres.

(Myat et al., 2005)

The Df(3L)GN24 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(3L)GN24 results in 13.1% X chromosome nondisjunction and 7.3% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.

(Harris et al., 2003)

Homozygous embryos have abnormal gut morphology; visceral mesoderm cells do not migrate dorsoventrally and dorsal midgut closure fails.

(Merabet et al., 2002)

Weak second site non-complementing phenotype with zipEbr and zipmhc-c6.1 : malformed phenotype penetrance 10-24%.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpphr4.

(Nicholls and Gelbart, 1998)

Shows a dose-sensitive interaction with pbhs.PB.

(Boube et al., 1997)

Deficient embryos show an uninterpretable mutant midgut phenotype.

(Bilder and Scott, 1995)
Stocks (2)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (4)
References (58)