A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Aberration Dmel\Df(3L)HR119

General Information
SymbolDmel\Df(3L)HR119SpeciesD. melanogaster
NameFlyBase IDFBab0002322
Feature typechromosomal_deletionCreated / Updated2006-08-22/2006-08-22
Formalized genetic data kst << bk1 << l(3)63Da << Sc2 << bk2 << dib
Sequence coordinates
Deleted segment63C6--63F7
Duplicated segment
Computed Breakpoints include 63C6;63F7
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
P{C28C}
(Wohlwill and Bonner, 1991)
Mutagen
X ray
(Wohlwill and Bonner, 1991)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Wohlwill and Bonner, 1991, Curtiss and Heilig, 1995, Hawkins et al., 1996, Coyne, 1996, Zhimulev et al., 1997.9.29, Deak et al., 1997, Mogila, 1998.3.19, Thomas et al., 1998, Zhimulev et al., 1998)
Breakpoints
63C6;63E
(Mogila, 1998.3.19, Wohlwill and Bonner, 1991, Curtiss and Heilig, 1995, Hawkins et al., 1996, Coyne, 1996)
63C6;63E9
(Thomas et al., 1998, Deak et al., 1997)
63C2;63F7
(Zhimulev et al., 1998, Zhimulev et al., 1997.9.29)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
hide Comments on Cytology
Limits of break 1 from polytene analysis (FBrf0054184) Limits of break 2 from polytene analysis (FBrf0098597)
 
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
ImpE2
(Paine-Saunders et al., 1990)
eIF5B
(Carrera et al., 2000)
sty
(Hacohen et al., 1998, Kramer et al., 1999)
Awh
(Wohlwill and Bonner, 1991, Curtiss and Heilig, 1995)
Sc2
(Wohlwill and Bonner, 1991, BDGP Project Members, 1994-1999)
Gad1
(Featherstone et al., 2000)
l(3)S103710
(Szeged Stock Center, 1998-)
l(3)S051022a
(Szeged Stock Center, 1998-)
l(3)S000903
(Deak et al., 1997)
l(3)SzB63Cd
(Deak et al., 1997)
l(3)S144507a
(Deak et al., 1997)
l(3)SzB63Cb
(Deak et al., 1997)
l(3)63Da
(Wohlwill and Bonner, 1991)
l(3)S144607a
(Deak et al., 1997)
l(3)S126615a
(Deak et al., 1997)
l(3)S014310b
(Deak et al., 1997)
l(3)S138415a
(Deak et al., 1997)
l(3)S140713a
(Deak et al., 1997)
l(3)S113204a
(Deak et al., 1997)
l(3)S138613a
(Deak et al., 1997)
l(3)S052908a
(Deak et al., 1997)
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
rasp
(Wohlwill and Bonner, 1991, Mogila, 1998.3.19, Micchelli et al., 2002)
kst
(BDGP Project Members, 1994-1999)
dib
(Wohlwill and Bonner, 1991)
l(3)neo9
(BDGP Project Members, 1994-1999)
l(3)63Bd
(Wohlwill and Bonner, 1991)
l(3)63Bc
(Wohlwill and Bonner, 1991)
l(3)63Bh
(Wohlwill and Bonner, 1991)
M(3)63B
(Wohlwill and Bonner, 1991)
l(3)63Ab
(Wohlwill and Bonner, 1991)
l(3)63Be
(Wohlwill and Bonner, 1991)
l(3)63Bb
(Wohlwill and Bonner, 1991)
l(3)09143
(BDGP Project Members, 1994-1999)
l(3)63Ba
(Wohlwill and Bonner, 1991)
l(3)63Aa
(Wohlwill and Bonner, 1991)
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Causes inviability or low viability in hybrid females when heterozygous with D.simulans chromosome.
(Coyne et al., 1998)
Deficient embryos show an uninterpretable mutant midgut phenotype.
(Bilder and Scott, 1995)
Dominantly suppresses the KrIf-1/+ eye phenotype.
(Carrera et al., 1998)
Heterozygosity for Df(3L)HR119 results in 1.9% X chromosome nondisjunction and 0.3% fourth chromosome nondisjunction in In(1)FM7/X ; svspa-pol females.
(Harris et al., 2003)
Shows no maternal enhancement of dpphr4.
(Nicholls and Gelbart, 1998)
The Df(3L)HR119 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3\'WP-2,wvar}2Lt insertion).
(Mason et al., 2004)
Weak second site non-complementing phenotype with zipEbr and zipmhc-c6.1: malformed phenotype penetrance 10-24%.
(Halsell and Kiehart, 1998)
hide Position Effect Variegation Data
  
hide Stocks ( 2 )
Bloomington
3649
Df(3L)HR119/TM6B, Tb+ ca1
Kyoto
107158
Df(3L)HR119/TM6B, Tb1 ca1
hide Notes on Origin
Discoverer
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
      hide Other Comments
      Used in D.melanogaster/D.simulans hybrids to map at least four non-overlapping regions on the D.simulans 3R that have effects on the species difference of cuticular hydrocarbon profile.
      (Coyne, 1996)
      "63C2;63F7" was stated as revision.
      (Zhimulev et al., 1997.9.29)
      "63C2;63F7" was stated as revision.
      (Zhimulev et al., 1998)
      hide Synonyms & Secondary IDs ( 4 )
      Reported As
      Symbol Synonym
      Df(3)63C6,63E
      (Curtiss and Heilig, 1995)
      Df(3L)Hr119
      (Hacohen et al., 1998)
      Df(3L)HR119
      (Wilson et al., 2006, Crest et al., 2007)
      HR119
      (Yamaguchi et al., 2001)
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 45 )
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        hide Recent research papers ( 2 )
        Crest et al., 2007, Genetics 175(2): 567--584
        Onset of the DNA replication checkpoint in the early Drosophila embryo. [FBrf0194644]
        Wilson et al., 2006, Genetics 173(3): 1455--1463
        High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster. [FBrf0194188]
        Show all research papers ...