Aberration Dmel\Df(3L)M21

General Information
Symbol	Dmel\Df(3L)M21	Species	D. melanogaster
Name		FlyBase ID	FBab0002333
Feature type	chromosomal_deletion

Computed Breakpoints include	62F;63B10
Deleted segment	62F--63B10
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	diepoxybutane (Wohlwill and Bonner, 1991)
Class of aberration (relative to progenitor)	chromosomal_deletion (Mogila, 1998.3.19, Wohlwill and Bonner, 1991)
Breakpoints	62F;63D (Wohlwill and Bonner, 1991, Mogila, 1998.3.19)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	msn << bk1 << rasp << bk2 << l(3)09143
Genetic mapping information
Comments
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0054184) Left limit of break 2 from inclusion of l(3)01029 (FBrf0067338) Right limit of break 2 from non-inclusion of l(3)09143 (FBrf0067338)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Hsp83 (Wohlwill and Bonner, 1991, Dickson et al., 1996) l(3)01029 (BDGP Project Members, 1994-1999) l(3)S085212 (Szeged Stock Center, 1998-) l(3)S103012b (Szeged Stock Center, 1998-) l(3)S103710 (Szeged Stock Center, 1998-) msn (BDGP Project Members, 1994-1999) rasp (Mogila, 1998.3.19, Amanai and Jiang, 2001, Micchelli et al., 2002) scramb2 (Acharya et al., 2006) Shab (Chopra et al., 2000) Spn (BDGP Project Members, 1994-1999)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	fang (Myat et al., 2005) gim (Myat et al., 2005) gloin (Myat et al., 2005) Hsp83 (BDGP Project Members, 1994-1999) kst (BDGP Project Members, 1994-1999) l(3)06803 (BDGP Project Members, 1994-1999) l(3)09143 (BDGP Project Members, 1994-1999) l(3)neo9 (BDGP Project Members, 1994-1999) l(3)S051022a (Szeged Stock Center, 1998-) l(3)S093909 (Szeged Stock Center, 1998-) S(CycE^JP)59S9 (Brumby et al., 2004) sls (BDGP Project Members, 1994-1999)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Lethal when heterozygous with Df(3L)HR218. (Wohlwill and Bonner, 1991)
NOT in combination with other aberrations	Df(3L)M21 embryos have disrupted tracheal branches. (Myat et al., 2005) Wild-type clones made in the ovaries of a mutant female, are significantly larger than clones of heterozygous mutant cells. This size difference is greater in clones initiated at 48 hours after egg laying (AEL) than 2 hours AEL. (Extavour and Garcia-Bellido, 2001) Dominantly suppresses the Kr^If-1/+ eye phenotype. (Carrera et al., 1998) Weak second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1: malformed phenotype penetrance 10-24%. (Halsell and Kiehart, 1998) Has no effect on phl::tor^12D.hs.sev when heterozygous with wild type. (Dickson et al., 1996) Deficient embryos show a variably penetrant mutant midgut phenotype: constrictions absent. (Bilder and Scott, 1995) Mutants exhibit a Minute phenotype: weak female fertility. (Wohlwill and Bonner, 1991)
Stocks ( 2 )
Bloomington	3650 Df(3L)M21, kni^ri-1 p^p/In(3LR)T33^Lf19^R, h¹ th¹ st¹ cu¹ sr¹
Kyoto	107159 Df(3L)M21, kni^ri-1 p^p/In(3LR)T33^Lf19^R, h¹ th¹ st¹ cu¹ sr¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(3L)M21 (Crest et al., 2007, Acharya et al., 2006, Casso et al., 2008, Chopra et al., 2000)
Name Synonym
Secondary FlyBase IDs

References ( 27 )

Generate a list of	All references relating to this aberration ( 27 )

List References by type	Research paper ( 23 ) Personal communication to FlyBase ( 2 ) FlyBase analysis ( 1 ) Stock list ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...