FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(3L)Pc
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General Information
Symbol
Df(3L)Pc
Species
D. melanogaster
Name
Deficiency (3L) Polycomb
FlyBase ID
FBab0002338
Feature type
deficient_inversion
Also Known As
Df(3L)Asc, Df(3R)Pc, Df(3L)Pc(ASC)
Computed Breakpoints include

78C4-78C5;78C9-78D1;79E2-79E3

Features within 78D1--79C1
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
deficient_inversion
Class of aberration (relative to progenitor)
deficient_inversion
(Levine et al., 1997, Russell et al., 1996, Carpenter, 1994)
chromosomal_deletion
(Duffy et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Landecker et al., 1994)
Breakpoints

78D1-78D2;79A4-79C1

(Duffy et al., 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Landecker et al., 1994, Phillips and Shearn, 1990)

78C1-78C5;78C9-78D3;79E2

(Levine et al., 1997, Russell et al., 1996, Carpenter, 1994)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

l(3)07615 << bk1 << Pc << bk2 << l(3)00534 << l(3)78Da << bk3

Genetic mapping information
Comments
Comments on Cytology

Right breakpoint of Df(3L)Pc-MK maps approximately 70kb proximal to the right breakpoint of Df(3L)Pc.

(Lin et al., 1996)

Ref: FBrf0039217.

(Phillips and Shearn, 1990)

Left limit of break 1 from non-inclusion of Ilk (FBrf0075380) Right limit of break 1 from polytene analysis (FBrf0075380) Left limit of break 2 from polytene analysis (FBrf0075380) Right limit of break 2 from non-inclusion of l(3)00534 (FBrf0067338) Limits of break 3 from polytene analysis (FBrf0075380)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    The penetrance of the extra sex comb teeth phenotype seen in Df(3L)Pc flies is suppressed by Df(2R)Pu-D17 or Df(2L)cl-h3.

    (Gildea et al., 2000)

    The phenotype of heterozygous Df(3L)Pc males is partially suppressed by Dp(3;3)S2a3.

    (Phillips and Shearn, 1990)
    NOT in combination with other aberrations

    Heterozygous males have ectopic sex combs on the second and third legs (37% and 6% of flies respectively).

    (Qi et al., 2006)

    14.5% of heterozygous males have sex combs on the second and/or third legs.

    (Swaminathan et al., 2005)

    Heterozygous adults show transformation of second and third legs to first leg. The frequency and severity of this transformation is suppressed by mod(mdg4)ul or mod(mdg4)T16. Dominantly suppresses the effect of mod(mdg4)ul on the y2 phenotype.

    (Gerasimova and Corces, 1998)

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    (Duffy et al., 1996)

    Heterozygosity for this deletion suppresses the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    Shows no significant dominant suppression of the nos mutant phenotype.

    (Pelegri and Lehmann, 1994)

    Heterozygous males have sex comb teeth on all legs with an average of over 4 teeth per leg on the second leg and over 2 teeth per leg on the third leg.

    (Phillips and Shearn, 1990)
    Stocks (5)
    Notes on Origin
    Discoverer

    Jurgens.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    "78C1--5;78C9--D3;79E2+" was stated as revision. "deficient_inversion ; SO:1000171" was stated as revision.

    (Carpenter, 1994)
    Synonyms and Secondary IDs (6)
    Reported As
    Symbol Synonym
    Df(3L)ASC
    (Jurgens et al., 1984)
    Df(3L)Asc
    (Fyodorov et al., 2004, Gildea et al., 2000)
    Df(3L)Pc
    (Kugler et al., 2011, Qi et al., 2006)
    Df(3L)Pc(ASC)
    (Levine et al., 1997, Levine et al., 1994)
    Df(3R)Pc
    (Swaminathan et al., 2005, Gerasimova and Corces, 1998)
    Name Synonyms
    Deficiency (3L) Polycomb
    Secondary FlyBase IDs
      References (29)