Aberration Dmel\Df(3L)R-G7

General Information
Symbol	Dmel\Df(3L)R-G7	Species	D. melanogaster
Name	Deficiency (3L) Roughened	FlyBase ID	FBab0002347
Feature type	chromosomal_deletion
Also Known As	Df(3L)R^G7

Computed Breakpoints include	62B9;62E7
Deleted segment	62B7--62E6 (Estimated cytology)
Map ( GBrowse )	Untitled Document
Sequence coordinates	3L:1,861,374..1,865,717 (Df(3L)R-G7:bk1) (Cook et al., 2010.2.12) 3L:2,526,381..2,557,148 (Df(3L)R-G7:bk2) (Cook et al., 2010.2.12)
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	R¹ (Sliter et al., 1989)
Mutagen	gamma ray (Sliter et al., 1989)
Class of aberration (relative to progenitor)	chromosomal_deletion (Mason, 19??, Pauli et al., 1995, Coyne, 1996, Zhimulev et al., 1997.9.29, Zhimulev et al., 1998)
Breakpoints	62B2-62B8;62F2-62F5 (Pauli et al., 1995) 62B8-62B9;62F2-62F5 (Sliter et al., 1989, Mason, 19??, Coyne, 1996) 62B9;62E7 (Zhimulev et al., 1997.9.29, Zhimulev et al., 1998)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	Cdc37 << bk1 << R << ecd << bk2 << msn
Genetic mapping information
Comments
Comments on Cytology
	The left Df(3L)R-G7 breakpoint lies within R or CG12025 or in the region between them, and lies in the range 3L:1861374..1865717 (R5) (predicted cytology: 62B7). (Cook et al., 2010.2.12) The right Df(3L)R-G7 breakpoint lies within CG32295 or msn or in the region between them, and lies in the range 3L:2526381..2557148 (R5) (predicted cytology: 62E5-62E6) based on the following evidence. (Cook et al., 2010.2.12) Left limit of break 1 from polytene analysis (FBrf0098597) Right limit of break 1 from polytene analysis (FBrf0049893) Limits of break 2 from polytene analysis (FBrf0098597)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Aprt (Sliter et al., 1989) Dbx (Lacin et al., 2009) ecd (Sorrentino et al., 2002) l(3)L1910 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)S093909 (Szeged Stock Center, 1998-) l(3)S140410 (Szeged Stock Center, 1998-) mu2 (Wang et al., 1994) S(CycE^JP)59S9 (Brumby et al., 2004) sls (Szeged Stock Center, 1998-, Spradling et al., 1999, BDGP Project Members, 1994-1999, Harding et al., 1995)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Cdc37 (Cutforth and Rubin, 1994) fang (Myat et al., 2005) gim (Myat et al., 2005) gloin (Myat et al., 2005) l(3)02104 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)06265 (BDGP Project Members, 1994-1999) l(3)Lak (Cripps et al., 1994) l(3)neo8 (Spradling et al., 1999) l(3)S085212 (Szeged Stock Center, 1998-) msn (Spradling et al., 1999, BDGP Project Members, 1994-1999) S(CycE^JP)59S18 (Brumby et al., 2004) Spn (BDGP Project Members, 1994-1999) Tmhs (Spradling et al., 1999, BDGP Project Members, 1994-1999)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Lethal in combination with Df(3L)BSC116. Inferred to overlap with: Df(3L)BSC116. (Andrade and Cook, 2005.7.22)
NOT in combination with other aberrations	Df(3L)R-G7 embryos show defects in tracheal cell migration. (Myat et al., 2005) The Df(3L)R-G7 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Heterozygosity for Df(3L)R-G7 results in 1.9% X chromosome nondisjunction and 1.2% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females. (Harris et al., 2003) Dominantly enhances the Kr^If-1/+ eye phenotype. (Carrera et al., 1998) Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome. (Coyne et al., 1998) No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1. (Halsell and Kiehart, 1998) Deficient embryos show an uninterpretable mutant midgut phenotype. (Bilder and Scott, 1995) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995)
Stocks ( 3 )
Bloomington	2400 Df(3L)R-G7, rho^ve-1/TM6B, Tb¹
Kyoto	107311 Df(3L)R-G7, rho^ve-1/TM6B, Tb⁺ 103300 Df(3L)R-G7, rho^ve-1 / TM6B, Tb⁺
Notes on Origin
Discoverer	J. Bonner. T. Sliter. (Mason, 19??)
	Revertant (Sliter et al., 1989)
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	"62B9;62E7" was stated as revision. (Zhimulev et al., 1997.9.29, Zhimulev et al., 1998) Used in D.melanogaster/D.simulans hybrids to map at least four non-overlapping regions on the D.simulans 3R that have effects on the species difference of cuticular hydrocarbon profile. (Coyne, 1996) Distal breakpoints of Df(3L)R-E and Df(3L)R-G7 are not distinguishable cytogenetically. (Sliter et al., 1989)
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	Df(3)R-G7 (Anderson et al., 2006) Df(3L)R^G7 (Brumby et al., 2004, Ishimaru et al., 1999, Cripps et al., 1994, Cutforth and Rubin, 1994, Mason, 19??, Sliter et al., 1989) Df(3L)RG-7 (Harding et al., 1995) Df(3L)RG7 (Pauli et al., 1995) Df(3L)R-G7 (Crest et al., 2007, Cook et al., 2010.2.12, Lacin et al., 2009, Slack et al., 2006)
Name Synonym	Deficiency (3L) Roughened
Secondary FlyBase IDs

References ( 44 )

Generate a list of	All references relating to this aberration ( 44 )

List References by type	Research paper ( 36 ) Personal communication to FlyBase ( 5 ) FlyBase analysis ( 1 ) Stock list ( 1 ) Book ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...