FlyBase Aberration Report: Dmel\Df(3L)R-G7

General Information

Symbol

Df(3L)R-G7

Species

D. melanogaster

Name

Deficiency (3L) Roughened

FlyBase ID

FBab0002347

Feature type

chromosomal_deletion

Also Known As

Df(3L)R^G7

Computed Breakpoints include

62B9;62E7

Features within 62B7--62E6 (Estimated cytology)

Genomic Maps

JBrowse

Sequence coordinates

3L:1,861,374..1,865,717 (Df(3L)R-G7:bk1)

(Cook et al., 2010.2.12)

3L:2,526,381..2,557,148 (Df(3L)R-G7:bk2)

(Cook et al., 2010.2.12)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Rap1^R-1

(Sliter et al., 1989)

Mutagen

gamma ray

(Sliter et al., 1989)

Class of aberration (relative to wild type)

chromosomal_deletion

(Cook et al., 2010.2.12, FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Zhimulev et al., 1998, Zhimulev et al., 1997.9.29, Coyne, 1996, Pauli et al., 1995, Mason, 19??)

Breakpoints

62B8-62B9;62F2-62F5

(Coyne, 1996, Sliter et al., 1989, Mason, 19??)

62B2-62B8;62F2-62F5

(Pauli et al., 1995)

62B9;62E7

(Zhimulev et al., 1998, Zhimulev et al., 1997.9.29)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

Cdc37 << bk1 << R << ecd << bk2 << msn

Genetic mapping information

Comments

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

(Marygold et al., 2007)

Comments on Cytology

The left Df(3L)R-G7 breakpoint lies within R or CG12025 or in the region between them, and lies in the range 3L:1861374..1865717 (R5) (predicted cytology: 62B7).

(Cook et al., 2010.2.12)

The right Df(3L)R-G7 breakpoint lies within CG32295 or msn or in the region between them, and lies in the range 3L:2526381..2557148 (R5) (predicted cytology: 62E5-62E6) based on the following evidence.

(Cook et al., 2010.2.12)

Left limit of break 1 from polytene analysis (FBrf0098597) Right limit of break 1 from polytene analysis (FBrf0049893) Limits of break 2 from polytene analysis (FBrf0098597)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Partially deleted / disrupted

Molecular Data

Completely deleted

mRpL23

(Marygold et al., 2007)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (84)

Related Comments

Phenotypic Data

In combination with other aberrations

Lethal in combination with Df(3L)BSC116. Inferred to overlap with: Df(3L)BSC116.

(Andrade and Cook, 2005.7.22)

NOT in combination with other aberrations

Flies heterozygous for the deletion do not show a Minute bristle phenotype.

(Marygold et al., 2007)

Df(3L)R-G7 embryos show defects in tracheal cell migration.

(Myat et al., 2005)

The Df(3L)R-G7 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(3L)R-G7 results in 1.9% X chromosome nondisjunction and 1.2% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females.

(Harris et al., 2003)

Dominantly enhances the Kr^If-1/+ eye phenotype.

(Carrera et al., 1998)

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1.

(Halsell and Kiehart, 1998)

Deficient embryos show an uninterpretable mutant midgut phenotype.

(Bilder and Scott, 1995)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Stocks (3)

Bloomington

2400

Df(3L)R-G7, rho^ve-1/TM6B, Tb¹

Kyoto

107311

Df(3L)R-G7, rho^ve-1/TM6B, Tb⁺

103300

Df(3L)R-G7, rho^ve-1 / TM6B, Tb⁺

Notes on Origin

Discoverer

J. Bonner.

T. Sliter.

(Mason, 19??)

Revertant

(Sliter et al., 1989)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

"62B9;62E7" was stated as revision.

(Zhimulev et al., 1998, Zhimulev et al., 1997.9.29)

Used in D.melanogaster/D.simulans hybrids to map at least four non-overlapping regions on the D.simulans 3R that have effects on the species difference of cuticular hydrocarbon profile.

(Coyne, 1996)

Distal breakpoints of Df(3L)R-E and Df(3L)R-G7 are not distinguishable cytogenetically.

(Sliter et al., 1989)

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Df(3)R-G7

(Anderson et al., 2006)

Df(3L)R-G7

(Ribot et al., 2022, Lattao et al., 2021, Syed et al., 2017, Cuykendall et al., 2014, Galindo et al., 2014, Cook et al., 2010.2.12, Lacin et al., 2009, Crest et al., 2007, Slack et al., 2006)

Df(3L)R^G7

(Brumby et al., 2004, Ishimaru et al., 1999, Cripps et al., 1994, Cutforth and Rubin, 1994, Sliter et al., 1989, Mason, 19??)

Df(3L)RG-7

(Harding et al., 1995)

Df(3L)RG7

(Pauli et al., 1995)

Name Synonyms

Deficiency (3L) Roughened

Secondary FlyBase IDs

References (51)

Report Sections

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