Aberration Dmel\Df(3L)R-R2

General Information
Symbol	Dmel\Df(3L)R-R2	Species	D. melanogaster
Name	Deficiency (3L) Roughened	FlyBase ID	FBab0002348
Feature type	chromosomal_deletion
Also Known As	Df(3L)R^R2

Computed Breakpoints include	62B2-62B3;62D3-62D5
Deleted segment	62B2--62D5
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_deletion
Breakpoints	62B2-62B4;62D3-62D5 (Sliter et al., 1989)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << l(3)62Bc << ecd << bk2
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0049893) Right limit of break 1 from inclusion of α-Spec (FBrf0068573) Limits of break 2 from polytene analysis (FBrf0049893)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Cdc37 (Cutforth and Rubin, 1994) dlt (Lee et al., 1993) ecd (Sliter et al., 1989) l(3)62Bb (Lee et al., 1993) l(3)62Bc (Lee et al., 1993) Tmhs (Lee et al., 1993) α-Spec (Lee et al., 1993, de Cuevas et al., 1996)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Stocks ( 0 )

Notes on Origin
Discoverer	J. Bonner.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	Df(3L)R+R2 (Gaziova et al., 2004) Df(3L)R⁺R2 (Henrich et al., 1993) Df(3L)R^R2 (Sliter et al., 1989, Cutforth and Rubin, 1994) Df(3L)R-R2
Name Synonym	Deficiency (3L) Roughened
Secondary FlyBase IDs

References ( 10 )
Research paper	Avidor-Reiss et al., 2004, Cell 117(4): 527--539 Decoding cilia function; defining specialized genes required for compartmentalized cilia biogenesis. [FBrf0174448] Gaziova et al., 2004, Development 131(11): 2715--2725 Cell-autonomous roles of the ecdysoneless gene in Drosophila development and oogenesis. [FBrf0179218] Lee et al., 1997, Development 124(2): 353--362 alpha-Spectrin is required for ovarian follicle monolayer integrity in Drosophila melanogaster. [FBrf0092605] de Cuevas et al., 1996, Development 122(12): 3959--3968 -spectrin is required for germline cell division and differentiation in the Drosophila ovary. [FBrf0091300] Cutforth and Rubin, 1994, Cell 77(7): 1027--1036 Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila. [FBrf0072892] Henrich et al., 1993, Dev. Genet. 14(5): 369--377 Developmental requirements for the ecdysoneless (ecd) locus in Drosophila melanogaster. [FBrf0065422] Lee et al., 1993, J. Cell Biol. 123(6 Pt. 2): 1797--1809 Cell shape and interaction defects in -spectrin mutants of Drosophila melanogaster. [FBrf0068573] Sliter et al., 1989, Genetics 123: 327--336 The genetics of the Dras3-Roughened-ecdysoneless chromosomal region (62B3-4 to 62D3-4) in Drosophila melanogaster: analysis of recessive lethal mutations. [FBrf0049893]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]