Aberration Dmel\Df(3L)W10

General Information
Symbol	Dmel\Df(3L)W10	Species	D. melanogaster
Name	Deficiency (3L) Wrinkled	FlyBase ID	FBab0002357
Feature type	chromosomal_deletion
Also Known As	Df(3L)WR10, W10, Df(3L)W^r10

Computed Breakpoints include	75A6-75A7;75C2
Deleted segment	75A6--75C2
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray (Abbott and Lengyel, 1991)
Class of aberration (relative to progenitor)	chromosomal_deletion (Segraves and Hogness, 1990, Birchler et al., 1994, Abbott and Lengyel, 1991, Pauli et al., 1995, Harbecke and Lengyel, 1995, Addison et al., 1995, Prout et al., 1997, Deak et al., 1997)
Breakpoints	75A6-75A7;75C1-75C2 (Prout et al., 1997, Deak et al., 1997) 75A6-75A7;75C5-75C7 (Addison et al., 1995) 75A6-76A7;75C1-75C2 (Segraves and Hogness, 1990) 75A;75C1-75C2 (Abbott and Lengyel, 1991) 75B3-75B6;75C (Harbecke and Lengyel, 1995) 75B3-75B6;75C1-75C2 (Pauli et al., 1995) 75B3;75C (Birchler et al., 1994)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << rhea << bk2 << not
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Segraves and Hogness, 1990)
Comments on Cytology
	Ref: FBrf0051843. (Abbott and Lengyel, 1991) Left limit of break 1 from polytene analysis (FBrf0051843) Right limit of break 1 from polytene analysis (FBrf0082995) Left limit of break 2 from polytene analysis (citation unavailable) Right limit of break 2 from polytene analysis (FBrf0051843)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Eip75B (Spradling et al., 1999, Segraves and Hogness, 1984, BDGP Project Members, 1994-1999) l(3)rL061 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)S000107 (Szeged Stock Center, 1998-, Deak et al., 1997) l(3)S000625a (Szeged Stock Center, 1998-) l(3)S001717 (Szeged Stock Center, 1998-) l(3)S005302a (Szeged Stock Center, 1998-) l(3)S012613b (Deak et al., 1997) l(3)S017014a (Szeged Stock Center, 1998-) l(3)S024135 (Szeged Stock Center, 1998-) l(3)S034305 (Szeged Stock Center, 1998-) l(3)S044823 (Szeged Stock Center, 1998-) l(3)S045608 (Szeged Stock Center, 1998-) l(3)S064316a (Deak et al., 1997) l(3)S080707a (Deak et al., 1997) l(3)S097001 (Szeged Stock Center, 1998-, Deak et al., 1997) l(3)S102211 (Szeged Stock Center, 1998-) l(3)S103408 (Szeged Stock Center, 1998-) l(3)S141110 (Szeged Stock Center, 1998-, Deak et al., 1997) l(3)S146004 (Szeged Stock Center, 1998-) l(3)S147006 (Szeged Stock Center, 1998-) not (BDGP Project Members, 1994-1999, Martin et al., 1995) rhea (Prout et al., 1997) rpr (White et al., 1994, Sonnenfeld and Jacobs, 1995, Fujikawa et al., 1995) Su(rst)C451 (Tanenbaum et al., 2000) term (Baldarelli et al., 1988) W (Spradling et al., 1999, BDGP Project Members, 1994-1999, Harbecke and Lengyel, 1995, Fujikawa et al., 1995)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	aos (Gaengel and Mlodzik, 2003) Cat (Spradling et al., 1999) HipHop (BDGP Project Members, 1994-1999) l(3)02634 (BDGP Project Members, 1994-1999) l(3)S004021 (Szeged Stock Center, 1998-) l(3)S073002a (Szeged Stock Center, 1998-) S(CycE^JP)3.1 (Brumby et al., 2004) tws (Szeged Stock Center, 1998-) Wow (Birchler et al., 1994)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Dominantly enhances the Kr^If-1/+ eye phenotype. (Carrera et al., 1998) Causes inviability or low viability in hybrid females when heterozygous with D.simulans chromosome. (Coyne et al., 1998) Intermediate second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1: malformed phenotype penetrance 25-75%. (Halsell and Kiehart, 1998) Shows no maternal enhancement of dpp^hr4. (Nicholls and Gelbart, 1998) Deficient embryos show a mutant midgut phenotype: posterior constriction forms anterior to normal site, anterior constriction fails to form. (Bilder and Scott, 1995) Homozygous embryos do not complete head involution and germband shortening, and tracheae are disrupted. Maintenance of the midgut epithelium, formation of midgut constrictions and elongation of the Malpighian tubules are variable. (Harbecke and Lengyel, 1995) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) Number of cells expressing midline glial cell markers in the embryonic CNS is increased by 60%. (Sonnenfeld and Jacobs, 1995) Homozygotes show the full cell death defective phenotype. (White et al., 1994) 75B puff is absent. (Segraves and Hogness, 1990)
Stocks ( 2 )
Bloomington	2608 Df(3L)W10, ru¹ h¹ Cap-H2^TH1 Sb^sbd-2/TM6B, Tb¹
Kyoto	107428 Df(3L)W10, ru¹ h¹ Sb^sbd-2/TM6B, Tb¹
Notes on Origin
Discoverer	Segraves.
	Separable from: Cap-H2[TH1]. (Hartl et al., 2008) The Cap-H2[TH1] mutation was found on the Df(3L)W10 chromosome. (Hartl et al., 2008)
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 13 )
Reported As
Symbol Synonym	Df(3L)w10 (Gaengel and Mlodzik, 2003) Df(3L)W10 (Hartl et al., 2008) Df(3L)W^+R Df(3L)W^r10 (Addison et al., 1995) Df(3L)W^R10 (Segraves and Hogness, 1990) Df(3L)W^R+10 (Abbott and Lengyel, 1991) Df(3L)W^rv Df(3L)WR10 (Sonnenfeld and Jacobs, 1995, Prout et al., 1997, Hengartner, 1994, Sonnenfeld and Jacobs, 1995, White et al., 1994, Hirose et al., 2001) Df(3L)W-R10 W10 (Provost et al., 2006, Hirose et al., 2001) W^+R10 (Baldarelli et al., 1988) W^R10 (Fujikawa et al., 1995)
Name Synonym	Deficiency (3L) Wrinkled
Secondary FlyBase IDs

References ( 48 )

Generate a list of	All references relating to this aberration ( 48 )

List References by type	Research paper ( 40 ) Supplementary material ( 1 ) Review ( 1 ) Personal communication to FlyBase ( 1 ) Abstract ( 2 ) FlyBase analysis ( 1 ) Stock list ( 1 ) Book ( 1 )
Recent research papers (0)
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Recent reviews (0)
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