FB2025_01 , released February 20, 2025
Aberration: Dmel\Df(3L)W10
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General Information
Symbol
Df(3L)W10
Species
D. melanogaster
Name
Deficiency (3L) Wrinkled
FlyBase ID
FBab0002357
Feature type
chromosomal_deletion
Also Known As
Df(3L)WR10, W10, Df(3L)Wr10
Computed Breakpoints include

75A6-75A7;75C2

Features within 75A6--75C2
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Abbott and Lengyel, 1991)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Deak et al., 1997, Prout et al., 1997, Addison et al., 1995, Harbecke and Lengyel, 1995, Pauli et al., 1995, Birchler et al., 1994, Abbott and Lengyel, 1991, Segraves and Hogness, 1990)
Breakpoints

75A6-76A7;75C1-75C2

(Segraves and Hogness, 1990)

75A;75C1-75C2

(Abbott and Lengyel, 1991)

75B3;75C

(Birchler et al., 1994)

75B3-75B6;75C1-75C2

(Pauli et al., 1995)

75B3-75B6;75C

(Harbecke and Lengyel, 1995)

75A6-75A7;75C5-75C7

(Addison et al., 1995)

75A6-75A7;75C1-75C2

(Deak et al., 1997, Prout et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << rhea << bk2 << not

Genetic mapping information
Comments

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

(Marygold et al., 2007)

Breakpoint(s) molecularly mapped

(Segraves and Hogness, 1990)
Comments on Cytology

Ref: FBrf0051843.

(Abbott and Lengyel, 1991)

Left limit of break 1 from polytene analysis (FBrf0051843) Right limit of break 1 from polytene analysis (FBrf0082995) Left limit of break 2 from polytene analysis (citation unavailable) Right limit of break 2 from polytene analysis (FBrf0051843)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    Flies heterozygous for the deletion do not show a Minute bristle phenotype.

    (Marygold et al., 2007)

    The wing discs of Df(3L)W10/+ mutant third instar larvae exhibit reduced levels of apoptosis in response to X-ray induced irradiation with 4000 rads compared to controls.

    (Brodsky et al., 2004)

    Dominantly enhances the KrIf-1/+ eye phenotype.

    (Carrera et al., 1998)

    Causes inviability or low viability in hybrid females when heterozygous with D.simulans chromosome.

    (Coyne et al., 1998)

    Intermediate second site non-complementing phenotype with zipEbr and zipmhc-c6.1 : malformed phenotype penetrance 25-75%.

    (Halsell and Kiehart, 1998)

    Shows no maternal enhancement of dpphr4.

    (Nicholls and Gelbart, 1998)

    Deficient embryos show a mutant midgut phenotype: posterior constriction forms anterior to normal site, anterior constriction fails to form.

    (Bilder and Scott, 1995)

    Homozygous embryos do not complete head involution and germband shortening, and tracheae are disrupted. Maintenance of the midgut epithelium, formation of midgut constrictions and elongation of the Malpighian tubules are variable.

    (Harbecke and Lengyel, 1995)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    Number of cells expressing midline glial cell markers in the embryonic CNS is increased by 60%.

    (Sonnenfeld and Jacobs, 1995)

    Homozygotes show the full cell death defective phenotype.

    (White et al., 1994)

    75B puff is absent.

    (Segraves and Hogness, 1990)
    Stocks (2)
    Notes on Origin
    Discoverer

    Segraves.

     

    Separable from: Cap-H2TH1.

    (Hartl et al., 2008)

    The Cap-H2TH1 mutation was found on the Df(3L)W10 chromosome.

    (Hartl et al., 2008)
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (13)
    References (54)