Aberration Dmel\Df(3L)fz-CAL5

General Information
Symbol	Dmel\Df(3L)fz-CAL5	Species	D. melanogaster
Name	Deficiency (3L) frizzled	FlyBase ID	FBab0002369
Feature type	chromosomal_deletion

Computed Breakpoints include	70C2-70C6;70E1
Deleted segment	70C2--70E1
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	P-element activity
Class of aberration (relative to progenitor)	chromosomal_deletion (Landecker et al., 1994)
Breakpoints	70C2-70C7;70E1-70E3 (Landecker et al., 1994)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	l(3)05871 << bk1 << btl << fz << bk2 << Mpcp
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0076124) Right limit of break 1 from inclusion of dev (FBrf0067338) Left limit of break 2 from polytene analysis (FBrf0076124) Right limit of break 2 from non-inclusion of Mpcp (FBrf0067338)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	balloon (Ghabrial et al., 2011) btl (Netter et al., 1998, Spradling et al., 1999, BDGP Project Members, 1994-1999) constricted (Ghabrial et al., 2011) E(br)121 (Ward et al., 2003) Hsc70Cb (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)j2E11 (BDGP Project Members, 1994-1999) Pex1 (Spradling et al., 1999) stwl (Spradling et al., 1999)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	bru-3 (BDGP Project Members, 1994-1999, Spradling et al., 1999) l(3)00421 (BDGP Project Members, 1994-1999) l(3)j5B2 (BDGP Project Members, 1994-1999) l(3)j6C3 (BDGP Project Members, 1994-1999) l(3)L0499 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)s9999 (BDGP Project Members, 1994-1999) Mpcp (Spradling et al., 1999, BDGP Project Members, 1994-1999) Pex1 (BDGP Project Members, 1994-1999) stv (Spradling et al., 1999, BDGP Project Members, 1994-1999) v(3)03699 (BDGP Project Members, 1994-1999)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Df(3L)fz-GF3b/Df(3L)fz-CAL5 embryos have large holes in the cuticle and many denticle belts are missing. (Landecker et al., 1994) Df(3L)fz-CAL5/Df(3L)fz-D21 lethal Df(3L)fz-CAL5/Df(3L)fz-M21 lethal
NOT in combination with other aberrations	The Df(3L)fz-CAL5 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) No effect on the eye pigment phenotype of w^T81. (Netter et al., 1998) Strong fz phenotype over fz
Stocks ( 2 )
Bloomington	5413 Df(3L)fz-CAL5/TM3, Sb¹
Kyoto	108213 Df(3L)fz-CAL5/TM3, Sb¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	Df(3L)fz-CAL (Mason et al., 2004) Df(3L)fz-CAL5 (Goodliffe et al., 2007, Ghabrial et al., 2011) Df(3L)fz-CALS (Ward et al., 2003)
Name Synonym	Deficiency (3L) frizzled
Secondary FlyBase IDs

References ( 13 )
Research paper	Ghabrial et al., 2011, PLoS Genet. 7(7): e1002087 A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system. [FBrf0214368] Goodliffe et al., 2007, BMC Mol. Biol. 8: 40 Coordinated regulation of Myc trans-activation targets by polycomb and the trithorax group protein Ash1. [FBrf0201535] Goodliffe et al., 2005, Genes Dev. 19(24): 2941--2946 Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila. [FBrf0190544] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Moehring and Mackay, 2004, Genetics 167(3): 1249--1263 The quantitative genetic basis of male mating behavior in Drosophila melanogaster. [FBrf0179348] Ward et al., 2003, Genetics 165(3): 1397--1415 Genetic modifier screens in Drosophila demonstrate a role for Rho1 signaling in ecdysone-triggered imaginal disc morphogenesis. [FBrf0167639] Spradling et al., 1999, Genetics 153(1): 135--177 The Berkeley Drosophila genome project gene disruption project. Single P-element insertions mutating 25% of vital Drosophila genes. [FBrf0111489] Netter et al., 1998, Genetics 149(1): 257--275 white+ transgene insertions presenting a dorsal/ventral pattern define a single cluster of homeobox genes that is silenced by the polycomb-group proteins in Drosophila melanogaster. [FBrf0102846] Landecker et al., 1994, Dev. Genet. 15(5): 425--434 Screen for enhancers of Polycomb and Polycomblike in Drosophila melanogaster. [FBrf0076124] Adler et al., 1987, Dev. Genet. 8(2): 99--119 Allelic variation at the frizzled locus of Drosophila. [FBrf0046044]
Personal communication to FlyBase	BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]