FlyBase Aberration Report: Dmel\Df(3L)fz-D21

General Information

Symbol

Df(3L)fz-D21

Species

D. melanogaster

Name

FlyBase ID

FBab0002370

Feature type

chromosomal_deletion

Also Known As

fz^D21, Df(3L)fz^D21, Df(3L)fzD21

Computed Breakpoints include

70D2;70E8

Features within 70D2--70E8

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

gamma ray

(Smyth and Belote, 1999)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Smyth and Belote, 1999, Deak et al., 1997, Nambu and Nambu, 1996, Harbecke and Lengyel, 1995, Pauli et al., 1995, Carpenter, 1994, Landecker et al., 1994)

Breakpoints

70D2;70E8

(Smyth and Belote, 1999, Carpenter, 1994)

70D3;70E3-70E8

(Deak et al., 1997, Landecker et al., 1994)

70D;71F

(Harbecke and Lengyel, 1995, Pauli et al., 1995)

70D1-70D2;70E7

(Nambu and Nambu, 1996)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

Hsc70Cb << bk1 << D << shd << bk2 << gnu

Genetic mapping information

Comments

Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0075380) Right limit of break 1 from inclusion of D (FBrf0075380) Limits of break 2 from polytene analysis (FBrf0075380)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

gnu

(Tearle and Nusslein-Volhard, 1987, Freeman et al., 1986)

Hsc70Cb

(Burmester et al., 2000, BDGP Project Members, 1994-1999, Carpenter, 1994)

l(3)00421

(BDGP Project Members, 1994-1999)

l(3)S027714

(Burmester et al., 2000)

ome

(Chihara et al., 2005)

Pex1

(BDGP Project Members, 1994-1999)

Prosβ2

(Smyth and Belote, 1999)

stwl

(BDGP Project Members, 1994-1999)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location

Related Comments

Does not delete P{lacW}endos^S067006

(Burmester et al., 2000)

Phenotypic Data

In combination with other aberrations

Df(3L)fz-D21 Df(3L)fz2 embryos derived from fz²³/Df(3L)fz-D21 Df(3L)fz2 females show a "denticle lawn" cuticle phenotype.

(Rulifson et al., 2000)

NOT in combination with other aberrations

The Df(3L)fz-D21 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(3L)fz-D21 results in 1.1% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females.

(Harris et al., 2003)

Double mutants of fz²¹, fz²³ or Df(3L)fz-D21 with Df(3L)fz2 show variable embryonic segmentation defects ranging from a few extra denticles in the posterior part of some segments to complete replacement of naked cuticle with denticles. This phenotype is reminiscent of that for P{en1}wg^en11 loss of function.

(Bhanot et al., 1999)

Shows dominant enhancement of dominant haltere phenotype caused by Ubx¹⁹⁵ and Ubx^9.22.

(Burnette et al., 1999)

No effect on the eye pigment phenotype of w^T81.

(Netter et al., 1998)

Shows no maternal enhancement of dpp^hr4.

(Nicholls and Gelbart, 1998)

Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Exhibit dominant suppression of Pc.

(Carpenter, 1994)

Stocks (3)

Bloomington

3123

Df(3L)fz-D21, Diap1¹ st¹/TM6B, Tb¹

Kyoto

101591

Df(3L)fz-D21 / TM6B, e¹ Tb¹ ca¹

106862

Df(3L)fz-D21, Diap1¹ st¹/TM6B, Tb¹

Notes on Origin

Discoverer

Adler.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

"70D2;70E8" was stated as revision.

(Carpenter, 1994)

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

Df(3L)fz D21

(Kirkpatrick et al., 2004)

Df(3L)fz-D21

(Nakayama et al., 2009, Brun et al., 2006)

Df(3L)fz-d21

(Tearle and Nusslein-Volhard, 1987)

Df(3L)fz.D21

(Ren et al., 2009)

Df(3L)fz^D21

(Strutt and Strutt, 2007, Shimada et al., 2006, Harris et al., 2003, Shimada et al., 2001, Taylor et al., 1998, Jones et al., 1996)

Df(3L)fzD21

(Renault et al., 2003, Carrera et al., 1998, Pauli et al., 1995, Smith et al., 1993, Sullivan et al., 1993)

fz^D21

(Shimizu et al., 2011, Sato et al., 2006, Povelones et al., 2005, Ma et al., 2003, Gao et al., 2000, Rulifson et al., 2000, Bhanot et al., 1999, Chae et al., 1999, Usui et al., 1999, Adler et al., 1998, Adler et al., 1994, Krasnow and Adler, 1994, Park et al., 1994)

fzD21

(Chihara et al., 2005)

Name Synonyms

Secondary FlyBase IDs

FBal0039358

References (53)

Report Sections

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