FB2022_03, released June 9, 2022

Aberration: Dmel\Df(3L)fz-GS1a

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General Information
Symbol
Df(3L)fz-GS1a
Species
D. melanogaster
Name
FlyBase ID
FBab0002372
Feature type
chromosomal_deletion
Computed Breakpoints include

70D2;70E4-70E5

Features within 70D2--70E5
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Smyth and Belote, 1999, Duffy et al., 1996, Nambu and Nambu, 1996, Pauli et al., 1995, Carpenter, 1994, Landecker et al., 1994)
Breakpoints

70D2;70E7

(Carpenter, 1994)

70C6-70C15;70E4-70E6

(Duffy et al., 1996, Pauli et al., 1995, Landecker et al., 1994)

70C6-70C15;70E4-70E5

(Nambu and Nambu, 1996)

70D2;70E5

(Smyth and Belote, 1999)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

Hsc70Cb << bk1 << l(3)LG12 << Mpcp << bk2

Genetic mapping information
Comments
Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0075380) Right limit of break 1 from inclusion of D (FBrf0056113) Left limit of break 2 from polytene analysis (FBrf0076124) Right limit of break 2 from polytene analysis (FBrf0090707)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Df(3L)D-1rv16/Df(3L)fz-GS1a embryos exhibit variable segmentation defects: deletions removing half of the segments, weaker partial deletions and segment fusions. Embryos also exhibit variable defects in head development.

    (Russell et al., 1996)
    NOT in combination with other aberrations

    Heterozygotes show disrupted hygrosensing behaviour; a higher fraction of flies choose moist air (100% humidity) over dry air (0% humidity) compared to wild-type controls in a hygrosensory behaviour assay after five minutes.

    (Liu et al., 2007)

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    (Duffy et al., 1996)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    No, or little, enhancement of Pc

    (Carpenter, 1994)

    Homozygous embryos show transformation of the first abdominal segment to a more posterior segment. Asx1/+ ; Df(3L)fz-GS1a embryos completely lack the head, thorax and ventral denticle belts.

    (Landecker et al., 1994)
    Stocks (2)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    "70D2;70E7" was stated as revision.

    (Carpenter, 1994)
    Synonyms and Secondary IDs (7)
    Reported As
    Symbol Synonym
    Def-3125
    (Bonnay et al., 2013)
    Df(3L)fz-651a
    Df(3L)fz-GS1a
    (Bonnay et al., 2013, Shen et al., 2013, Mast et al., 2011, Crest et al., 2007, Liu et al., 2007, Brun et al., 2006)
    Df(3L)fzGS1a
    (Duffy et al., 1996)
    GS1a
    (Giniger et al., 1993)
    fz
    (Giniger et al., 1993)
    fzGs1
    (Chihara et al., 2005)
    Name Synonyms
    Secondary FlyBase IDs
      References (29)