Aberration Dmel\Df(3L)fz-GS1a

General Information
Symbol	Dmel\Df(3L)fz-GS1a	Species	D. melanogaster
Name		FlyBase ID	FBab0002372
Feature type	chromosomal_deletion

Computed Breakpoints include	70D2;70E4-70E5
Deleted segment	70D2--70E5
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen
Class of aberration (relative to progenitor)	chromosomal_deletion (Carpenter, 1994, Pauli et al., 1995, Duffy et al., 1996, Nambu and Nambu, 1996, Landecker et al., 1994, Smyth and Belote, 1999)
Breakpoints	70C6-70C15;70E4-70E5 (Nambu and Nambu, 1996) 70C6-70C15;70E4-70E6 (Landecker et al., 1994, Pauli et al., 1995, Duffy et al., 1996) 70D2;70E5 (Smyth and Belote, 1999) 70D2;70E7 (Carpenter, 1994)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	Hsc70Cb << bk1 << l(3)LG12 << Mpcp << bk2
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0075380) Right limit of break 1 from inclusion of D (FBrf0056113) Left limit of break 2 from polytene analysis (FBrf0076124) Right limit of break 2 from polytene analysis (FBrf0090707)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	btl (Spradling et al., 1999, Burmester et al., 2000, Klambt et al., 1992, Giniger et al., 1993, BDGP Project Members, 1994-1999, Carpenter, 1994, Russell et al., 1996) D (Burmester et al., 2000, Klambt et al., 1992, Carpenter, 1994, Nambu and Nambu, 1996, Russell et al., 1996, Carpenter, 1997.1.10) l(3)L0499 (Spradling et al., 1999, BDGP Project Members, 1994-1999) l(3)LG12 (Klambt et al., 1992) l(3)S072613a (Burmester et al., 2000) Mpcp (Spradling et al., 1999, BDGP Project Members, 1994-1999) Pex1 (Spradling et al., 1999, Burmester et al., 2000, Carpenter, 1994, Russell et al., 1996, Mast et al., 2011) shd (Giesen, 2001.1.24) stwl (Brun et al., 2006, Spradling et al., 1999)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	bru-3 (BDGP Project Members, 1994-1999, Spradling et al., 1999) Hsc70Cb (Spradling et al., 1999, Burmester et al., 2000, BDGP Project Members, 1994-1999, Carpenter, 1994) l(3)00421 (BDGP Project Members, 1994-1999) l(3)S027714 (Burmester et al., 2000) ome (Chihara et al., 2005) Pex1 (BDGP Project Members, 1994-1999) Prosβ2 (Smyth and Belote, 1999) stwl (BDGP Project Members, 1994-1999)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments
	Does not delete P{lacW}endos^S067006 (Burmester et al., 2000)
Phenotypic Data
In combination with other aberrations	Df(3L)D-1rv16/Df(3L)fz-GS1a embryos exhibit variable segmentation defects: deletions removing half of the segments, weaker partial deletions and segment fusions. Embryos also exhibit variable defects in head development. (Russell et al., 1996)
NOT in combination with other aberrations	Heterozygotes show disrupted hygrosensing behaviour; a higher fraction of flies choose moist air (100% humidity) over dry air (0% humidity) compared to wild-type controls in a hygrosensory behaviour assay after five minutes. (Liu et al., 2007) Dominantly causes tergite defects in less than 50% of run³ heterozygotes. (Duffy et al., 1996) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) No, or little, enhancement of Pc (Carpenter, 1994) Homozygous embryos show transformation of the first abdominal segment to a more posterior segment. Asx¹/+ ; Df(3L)fz-GS1a embryos completely lack the head, thorax and ventral denticle belts. (Landecker et al., 1994)
Stocks ( 2 )
Bloomington	3125 Df(3L)fz-GS1a, P{wA^R}66E/TM3, Sb¹
Kyoto	106864 Df(3L)fz-GS1a, P{wA^R}66E/TM3, Sb¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	"70D2;70E7" was stated as revision. (Carpenter, 1994)
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	Df(3L)fz-651a Df(3L)fzGS1a (Duffy et al., 1996) Df(3L)fz-GS1a (Crest et al., 2007, Liu et al., 2007, Mast et al., 2011, Brun et al., 2006) fz (Giniger et al., 1993) fzGs1 (Chihara et al., 2005) GS^1a (Giniger et al., 1993)
Name Synonym
Secondary FlyBase IDs

References ( 27 )

Generate a list of	All references relating to this aberration ( 27 )

List References by type	Research paper ( 21 ) Personal communication to FlyBase ( 3 ) FlyBase analysis ( 1 ) Stock list ( 1 ) Book ( 1 )
Recent research papers ( 1 )
	Mast et al., 2011, Dis. Model Mech. 4(5): 659--672 A Drosophila model for the Zellweger spectrum of peroxisome biogenesis disorders. [FBrf0215017] Show all research papers ...