Aberration Dmel\Df(3L)lxd15

General Information
Symbol	Dmel\Df(3L)lxd15	Species	D. melanogaster
Name	Deficiency (3L) low xanthine dehydrogenase	FlyBase ID	FBab0002385
Feature type	chromosomal_deletion
Also Known As	Df(3L)lxd¹⁵, lxd¹⁵

Computed Breakpoints include	67E1-67E4;68C10-68C15
Deleted segment	67E1--68C15
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray (Schott et al., 1986)
Class of aberration (relative to progenitor)	chromosomal_deletion (Phillips and Shearn, 1990, Schott et al., 1986)
Breakpoints	67E;68C10-68C15 (Phillips and Shearn, 1990) [];[] (Schott et al., 1986)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bk1 << hay << lxd << bk2
Genetic mapping information
Comments
Comments on Cytology
	Ref: FBrf0043787. (Phillips and Shearn, 1990) Left limit of break 1 from polytene analysis (FBrf0051989) Right limit of break 1 from inclusion of E(z) (FBrf0051989) Limits of break 2 from polytene analysis (FBrf0051989)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	E(z) (Phillips and Shearn, 1990) hay (Regan and Fuller, 1988) Mocs1 (Schott et al., 1986) rs (Schott et al., 1986) Sod (Schott et al., 1986)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	The total level of hydrocarbons and the level of 7-monoenes is significantly reduced in heterozygous males compared to controls. The total level of hydrocarbons and the level of 7,11-dienes is significantly decreased in heterozygous females compared to controls. (Wicker-Thomas and Jallon, 2000) Mutation does not affect the level of w expression in ph-p^lac+3 flies. (Fauvarque et al., 1995) Male sterile when heterozygous with hay^nc2. (Regan and Fuller, 1988) Homozygous lethal. (Schott et al., 1986)
Stocks ( 0 )

Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	Df(3L)lxd15 Df(3L)lxd¹⁵ (Mollaaghababa et al., 2001, Phillips and Shearn, 1990, Fauvarque et al., 1995) Df lxd¹⁵ (Wicker-Thomas and Jallon, 2000) lxd¹⁵ (Fuller, 1986, Schott et al., 1986)
Name Synonym	Deficiency (3L) low xanthine dehydrogenase
Secondary FlyBase IDs

References ( 12 )
Research paper	Boivin et al., 2003, Genetics 164(1): 195--208 Telomeric associated sequences of Drosophila recruit Polycomb-group proteins in vivo and can induce pairing-sensitive repression. [FBrf0158993] Mollaaghababa et al., 2001, Proc. Natl. Acad. Sci. U.S.A. 98(7): 3958--3963 Mutations in Drosophila heat shock cognate 4 are enhancers of Polycomb. [FBrf0135926] Wicker-Thomas and Jallon, 2000, Naturwissenschaften 87(2): 76--79 Role of Enhancer of zeste on the production of Drosophila melanogaster pheromonal hydrocarbons. [FBrf0125446] Fauvarque et al., 1995, Mech. Dev. 52(2-3): 343--355 Regulation of polyhomeotic transcription may involve local changes in chromatin activity in Drosophila. [FBrf0083917] Jones and Gelbart, 1990, Genetics 126: 185--199 Genetic analysis of the enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster. [FBrf0051932] Phillips and Shearn, 1990, Genetics 125: 91--101 Mutations in polycombeotic, a Drosophila Polycomb-group gene, cause a wide range of maternal and zygotic phenotypes. [FBrf0051989] Regan and Fuller, 1988, Genes Dev. 2: 82--92 Interacting genes that affect microtubule function: the nc2 allele of the haywire locus fails to complement mutations in the testis-specific -tubulin gene of Drosophila. [FBrf0048123] Fuller, 1986, Gall, 1986: 19--41 Genetic analysis of spermatogenesis in Drosophila: The role of the testis-specific -tubulin and interacting genes in cellular morphogenesis. [FBrf0066557] Schott et al., 1986, Biochem. Genet. 24: 509--527 Molybdenum hydroxylases in Drosophila. [FBrf0043787] Schott and Finnerty, 1983, Genetics 104(1/2): s62--s63 Characterization of lxd a molybdenum cofactor mutant. [FBrf0039525]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]