FlyBase Aberration Report: Dmel\Df(3L)pbl-X1

General Information

Symbol

Df(3L)pbl-X1

Species

D. melanogaster

Name

FlyBase ID

FBab0002391

Feature type

chromosomal_deletion

Also Known As

Df(3L)pbl^X1, Df(3L)pblX1, Df(3L)pb1-X1, Df(3L)pbl-X, pbl-X1

Computed Breakpoints include

65F3;66B10

Features within 65F6--66B8 (Estimated cytology)

Genomic Maps

JBrowse

Sequence coordinates

3L:7,356,061..7,357,525 (Df(3L)pbl-X1:bk1)

(Cook et al., 2010.2.12)

3L:8,132,130..8,141,044 (Df(3L)pbl-X1:bk2)

(Cook et al., 2010.2.12)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

(Hime and Saint, 1992)

Class of aberration (relative to wild type)

chromosomal_deletion

(Cook et al., 2010.2.12, FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Lai et al., 1998, Long et al., 1998, Deak et al., 1997, Fischer et al., 1997, Gonzalez-Reyes et al., 1997, Coyne, 1996, Fyrberg et al., 1994)

Breakpoints

65F3;66B9

(Long et al., 1998, Fyrberg et al., 1994, Hime and Saint, 1992)

65F3;66B10

(Lai et al., 1998, Deak et al., 1997, Fischer et al., 1997, Coyne, 1996)

65F3;66B3-66B9

(Gonzalez-Reyes et al., 1997)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

qm << bk1 << mus301 << lqf << bk2 << Nmt

Genetic mapping information

Comments

Comments on Cytology

The left Df(3L)pbl-X1 breakpoint lies within CTCF or pst or in the region between them, and lies in the range 3L:7349161..7350625 (R5) (predicted cytology: 65F6-65F6).

(Cook et al., 2010.2.12)

The right Df(3L)pbl-X1 breakpoint lies within CG7504 or mus301 or in the region between them, and lies in the range 3L:8125230..8134144 (R5) (predicted cytology: 66B7-66B8).

(Cook et al., 2010.2.12)

Limits of break 1 from polytene analysis (FBrf0055848) Limits of break 2 from polytene analysis (FBrf0086978)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Abd-B

(Ghabrial et al., 2011)

Ank2

(Koch et al., 2008)

Arp3

(Rajan et al., 2009, Berger et al., 2008, Fyrberg et al., 1994)

Cds

(Ghabrial et al., 2011)

Clk

(Allada et al., 1998)

ivy

(Ghabrial et al., 2011)

l(3)07217

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(3)j1D5

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(3)S072611

(Szeged Stock Center, 1998-, Deak et al., 1997)

lqf

(Csikós et al., 2009, Cadavid et al., 2000, Szeged Stock Center, 1998-, Deak et al., 1997, Fischer et al., 1997)

ltl

(Cook, 2014.12.4)

msk

(Pepple et al., 2007, Baker et al., 2002)

mus301

(Gonzalez-Reyes et al., 1997)

nmo

(Choi and Benzer, 1994)

pbl

(Spradling et al., 1999, Szeged Stock Center, 1998-, Deak et al., 1997, Salzberg et al., 1997, BDGP Project Members, 1994-1999, Hime and Saint, 1992)

Rac2

(Sawamoto et al., 1999, Boutros et al., 1998)

smid

(Spradling et al., 1999, Long et al., 1998, Long et al., 1998, BDGP Project Members, 1994-1999)

stertorous

(Ghabrial et al., 2011)

Partially deleted / disrupted

Molecular Data

Completely deleted

eIF4E5

(Marygold et al., 2007)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (110)

Related Comments

Phenotypic Data

In combination with other aberrations

Fails to complement Df(3L)ZP1.

(Maroy, 1997.10.17)

NOT in combination with other aberrations

The size of the tracheal lumen is different to wild type in Df(3L)pbl-X1 embryos.

(Myat et al., 2005)

The Df(3L)pbl-X1 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(3L)pbl-X1 results in 1.3% X chromosome nondisjunction and 0.4% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females.

(Harris et al., 2003)

Shows dominant enhancement of dominant haltere phenotype caused by Ubx¹⁹⁵ and Ubx^9.22.

(Burnette et al., 1999)

Dominant suppressor of dsh^hs.sev.B mutant polarity phenotype.

(Boutros et al., 1998)

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1.

(Halsell and Kiehart, 1998)

Shows no maternal enhancement of dpp^hr4.

(Nicholls and Gelbart, 1998)

Deficient embryos show an uninterpretable mutant midgut phenotype.

(Bilder and Scott, 1995)

Stocks (2)

Bloomington

1420

w¹¹¹⁸; Df(3L)pbl-X1/TM6C, Sb¹

Kyoto

106707

Df(3L)pbl-X1/TM6B, Tb¹

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Used in D.melanogaster/D.simulans hybrids to map at least four non-overlapping regions on the D.simulans 3R that have effects on the species difference of cuticular hydrocarbon profile.

(Coyne, 1996)

Synonyms and Secondary IDs (12)

Reported As

Symbol Synonym

Df(3L)PBIX1

(Rajan et al., 2009)

Df(3L)Pbl

(Jenny et al., 2003)

Df(3L)pb-X1

(Harris et al., 2003)

Df(3L)pb1-X1

(Fanara et al., 2002, Spradling et al., 1999, Lai et al., 1998, Saeboe-Larssen et al., 1997)

Df(3L)pbl-X

(Jackson et al., 2005, Park et al., 2000)

Df(3L)pbl-X1

(Lee et al., 2018, Cook, 2014.12.4, Cuykendall et al., 2014, Galindo et al., 2014, Fernandes and Rao, 2011, Ghabrial et al., 2011, Miller et al., 2011, Cook et al., 2010.2.12, Elsaesser et al., 2010, Sinenko et al., 2010, Csikós et al., 2009, Merino et al., 2009, Berger et al., 2008, Wang et al., 2008, Avet-Rochex et al., 2007, Crest et al., 2007, Pepple et al., 2007, Wilson et al., 2006)

Df(3L)pbl-XI

(Deak et al., 1997)

Df(3L)pbl-x1

(Greaves et al., 1999)

Df(3L)pbl^X1

(Schumacher et al., 2004, Ghabrial and Schupbach, 1999, Boutros et al., 1998, Fischer et al., 1997, Gonzalez-Reyes et al., 1997, Maroy, 1997.10.17, Fyrberg et al., 1994)

Df(3L)pblX1

(Koch et al., 2008, Findley et al., 2003, Long et al., 1998, Long et al., 1998, Hime et al., 1997)

Df(3R)pbl^X1

(Lu et al., 1999)

pbl-X1

(Yamaguchi et al., 2001, Yamaguchi et al., 1999)

Name Synonyms

Secondary FlyBase IDs

References (77)

Report Sections