Aberration Dmel\Df(3L)st7P

General Information
Symbol	Dmel\Df(3L)st7P	Species	D. melanogaster
Name	Deficiency (3L) scarlet	FlyBase ID	FBab0002433
Feature type	chromosomal_deletion

Computed Breakpoints include	73A1;73A7
Deleted segment	73A1--73A7
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor	In(3L)P
Mutagen	gamma ray (Wemmer and Klaembt, 1995) X ray
Class of aberration (relative to progenitor)	chromosomal_deletion (Wemmer and Klaembt, 1995, Duffy et al., 1996, Tearle et al., 1989)
Breakpoints	73A1-73A2;73A7-73A9 (Tearle et al., 1989) 73A1;73A7 (Duffy et al., 1996) 73A;73A (Wemmer and Klaembt, 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	bul << bk1 << argos << l(3)73Ac << bk2 << tra
Genetic mapping information
Comments	Deficiency extends from position -25 to +90 (coordinate 0 is the inversion breakpoint in st) of the argos region. (Wemmer and Klaembt, 1995) +80 to +85. DNA coordinates (kb) of proximal breakpoints in the walk in region 73A-B of McKeown and Belote, which originates at the left breakpoint of In(3LR)st^a27 ('+' values to right, '-' values to left). Df(3L)st-E coordinates from Butler et al., 1986; coordinate 0 halfway between right breakpoints of Df(3L)st-E5 and Df(3L)st-E52; positive values to the left
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0049915) Right limit of break 1 from polytene analysis (FBrf0086390) Left limit of break 2 from polytene analysis (FBrf0049915) Right limit of break 2 from polytene analysis (FBrf0086390)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	aos (Gaengel and Mlodzik, 2003, BDGP Project Members, 1994-1999, Wemmer and Klaembt, 1995) l(3)73Aa (McKeown et al., 1987, Belote et al., 1990, Wemmer and Klaembt, 1995) l(3)73Ab (McKeown et al., 1987, Belote et al., 1990, Wemmer and Klaembt, 1995) l(3)73Ac (McKeown et al., 1987, Belote et al., 1990) l(3)73Ad (McKeown et al., 1987, Belote et al., 1990) l(3)73Ae (McKeown et al., 1987, Belote et al., 1990) l(3)73Af (McKeown et al., 1987, Belote et al., 1990) l(3)73Ag (McKeown et al., 1987, Belote et al., 1990) l(3)73Ah (McKeown et al., 1987, Belote et al., 1990) l(3)10532 (BDGP Project Members, 1994-1999) mbf1 (Jindra, 1999.3.12) st (McKeown et al., 1987, Belote et al., 1990, Wemmer and Klaembt, 1995)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Abl (McKeown et al., 1987, Belote et al., 1990) Baldspot (BDGP Project Members, 1994-1999) bul (Wemmer and Klaembt, 1995) l(3)73Bb (McKeown et al., 1987, Belote et al., 1990) l(3)73Bc (McKeown et al., 1987, Belote et al., 1990) mfs(3)73A (McKeown et al., 1987, Belote et al., 1990) Mo25 (BDGP Project Members, 1994-1999) Prosβ6 (McKeown et al., 1987, Belote et al., 1990) soba (McKeown et al., 1987, Belote et al., 1990, Wemmer and Klaembt, 1995) spd-2 (Giansanti et al., 2008) tra (Belote et al., 1985, McKeown et al., 1987, Belote et al., 1990)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	The tracheal system forms normally in homozygous embryos. (Ebner et al., 2002) Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome. (Coyne et al., 1998) Dominantly causes tergite defects in less than 50% of run³ heterozygotes. (Duffy et al., 1996)
Stocks ( 2 )
Bloomington	2997 Df(3L)st7P, In(3L)P/TM3, Ser¹
Kyoto	107517 Df(3L)st7P, In(3L)P/TM3, Ser¹
Notes on Origin
Discoverer	Bonner. Bonner. (Belote et al., 1990)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	Df(3L)7P (Belote et al., 1990) Df(3L)Pst-B7 Df(3L)st7 (Wemmer and Klaembt, 1995) Df(3L)st7P Df(3L)st-7P (Giansanti et al., 2008) PstB7
Name Synonym	Deficiency (3L) scarlet
Secondary FlyBase IDs

References ( 16 )
Research paper	Giansanti et al., 2008, Curr. Biol. 18(4): 303--309 Drosophila SPD-2 is an essential centriole component required for PCM recruitment and astral-microtubule nucleation. [FBrf0203058] Jindra et al., 2004, EMBO J. 23(17): 3538--3547 Coactivator MBF1 preserves the redox-dependent AP-1 activity during oxidative stress in Drosophila. [FBrf0179772] Gaengel and Mlodzik, 2003, Development 130(22): 5413--5423 Egfr signaling regulates ommatidial rotation and cell motility in the Drosophila eye via MAPK/Pnt signaling and the Ras effector Canoe/AF6. [FBrf0167499] Ebner et al., 2002, Gene 287(1-2): 55--66 Tracheal development in Drosophila melanogaster as a model system for studying the development of a branched organ. [FBrf0147036] Firth et al., 2000, Genetics 156(2): 733--748 Identification of genomic regions that interact with a viable allele of the Drosophila protein tyrosine phosphatase corkscrew. [FBrf0129810] Coyne et al., 1998, Genetics 150(3): 1091--1103 Relative paucity of genes causing inviability in hybrids between Drosophila melanogaster and D. simulans. [FBrf0105213] Duffy et al., 1996, Genetics 142(3): 839--852 Dosage-sensitive maternal modifiers of the Drosophila segmentation gene runt. [FBrf0086390] Wemmer and Klaembt, 1995, Genetics 140(2): 629--641 A genetic analysis of the Drosophila closely linked interacting genes bulge, argos and soba. [FBrf0082770] Belote et al., 1990, Genetics 125: 783--793 Cytogenetic analysis of chromosome region 73AD of Drosophila melanogaster. [FBrf0051976] Tearle et al., 1989, Genetics 122: 595--606 Cloning and characterization of the scarlet gene of Drosophila melanogaster. [FBrf0049915] McKeown et al., 1987, Cell 48: 489--499 A molecular analysis of transformer, a gene in Drosophila melanogaster that controls female sexual differentiation. [FBrf0045766] Belote et al., 1985, Cold Spring Harbor Symp. Quant. Biol. 50: 605--614 Control of sexual differentiation in Drosophila melanogaster. [FBrf0042175]
Personal communication to FlyBase	Jindra, 1999.3.12, ADRC-417B. ADRC-417B. [FBrf0107797] BDGP Project Members, 1994-1999, BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) BDGP Project Members, 1994-1999, Berkeley Drosophila Genome Project. (Computer file) [FBrf0067338]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]