FB2020_06, released Dec 22, 2020

Aberration: Dmel\Df(3L)th102

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General Information
Symbol
Df(3L)th102
Species
D. melanogaster
Name
Deficiency (3L) thread
FlyBase ID
FBab0002437
Feature type
chromosomal_deletion
Computed Breakpoints include

72A2;72D10

Features within 72A2--72D10
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Ashburner et al., 1980)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Elfring et al., 1998, Zhimulev et al., 1998, Zhimulev et al., 1997.9.29, Coyne, 1996, Duffy et al., 1996, Pauli et al., 1995, Brizuela et al., 1994, Tamkun et al., 1991, Ashburner et al., 1980)
Breakpoints

72B1;72D12

(Duffy et al., 1996, Pauli et al., 1995, Tamkun et al., 1991, Ashburner et al., 1980)

71F3-71F5;72D12

(Coyne, 1996, Brizuela et al., 1994)

72A2;72E12

(Zhimulev et al., 1998, Zhimulev et al., 1997.9.29)

72A1;72D12

(Elfring et al., 1998)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

Sgs6 << bk1 << l(3)72Ad << l(3)72Dn << bk2 << ms(3)72D

Genetic mapping information
Comments

This deletion removes a single ribosomal protein-coding gene (though other genes are also removed).

(Marygold et al., 2007)

Breakpoint(s) molecularly mapped

(Tamkun et al., 1992)
Comments on Cytology

Ashburner et al., 1980, D. I. S. 55: 193 reports cytology as 72B1 to 72D12, from cytological analysis it is thought the chromosome is deficient for 72A as well.

(Brizuela et al., 1994)

Limits of break 1 from polytene analysis (FBrf0098597) Left limit of break 2 from inclusion of l(3)72Dn (FBrf0082216) Right limit of break 2 from non-inclusion of ms(3)72D (FBrf0082216)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Dominant scutellar bristle phenotype is increased in trans to Df(3L)A27 to around 48%.

    (Melendez et al., 1995)
    NOT in combination with other aberrations

    Flies heterozygous for the deletion do not show a Minute bristle phenotype.

    (Marygold et al., 2007)

    The Df(3L)th102 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion).

    (Mason et al., 2004)

    Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

    (Coyne et al., 1998)

    Dominantly causes tergite defects in less than 50% of run3 heterozygotes.

    (Duffy et al., 1996)

    Mutation changes the level of w expression in ph-plac+3 flies; eye colour is darker.

    (Fauvarque et al., 1995)

    Adults heterozygous for Df(3L)brm11 or Df(3L)th102 have a high frequency of duplications of the anterior scutellar bristles (around 24%).

    (Melendez et al., 1995)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)

    Heterozygotes for Df(3L)th102 and Df(2L)JK12 have thin bristles and weakly outstretched wings.

    (Brizuela et al., 1994)
    Stocks (3)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    "72A2;72E12" was stated as revision.

    (Zhimulev et al., 1998, Zhimulev et al., 1997.9.29)

    Used in D.melanogaster/D.simulans hybrids to map at least four non-overlapping regions on the D.simulans 3R that have effects on the species difference of cuticular hydrocarbon profile.

    (Coyne, 1996)

    "71F3--71F5;72D12" was stated as revision.

    (Brizuela et al., 1994)

    Reduces the expression of homeotic genes.

    (Tamkun et al., 1992)
    Synonyms and Secondary IDs (8)
    Reported As
    Symbol Synonym
    Df(3L) th102
    (Zhimulev et al., 1998)
    Df(3L)th102
    (Popkova et al., 2012, Adamson et al., 2011, Cooper and Kennison, 2011, Cook, 2008.12.1, Stowers and Isacoff, 2007)
    Df(3L)th102
    (Mishra et al., 2020)
    Df(3L)thSS102
    (Ashburner et al., 1980)
    th102
    (Provost et al., 2006)
    thSS102
    (Velissariou and Ashburner, 1981)
    Δth102
    (Baas et al., 2011)
    Name Synonyms
    Deficiency (3L) thread
    Secondary FlyBase IDs
      References (48)