Aberration Dmel\Df(3R)110

General Information
Symbol	Dmel\Df(3R)110	Species	D. melanogaster
Name		FlyBase ID	FBab0002468
Feature type	chromosomal_deletion

Computed Breakpoints include	82C4;82F3
Deleted segment	82C4--82F3
Sequence coordinates
Member of large scale dataset(s)
Recent Updates
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FB2013_03
FB2013_02
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Nature of the Aberration
Cytological Order
Progenitor
Mutagen	gamma ray (Wasserman, 1991.4)
Class of aberration (relative to progenitor)	chromosomal_deletion (Carpenter, 1994, Pauli et al., 1995, Colas et al., 1995, Martin-Morris et al., 1997, Colas et al., 1999)
Breakpoints	82C4;82F (Colas et al., 1999) 82C4;82F3-82F7 (Carpenter, 1994, Martin-Morris et al., 1997) 82C;82F (Pauli et al., 1995, Colas et al., 1995)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	l(3)ry103 << bk1 << laf << l(3)82Fb << bk2 << corto
Genetic mapping information
Comments
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0075380) Left limit of break 2 from polytene analysis (FBrf0075380) Right limit of break 2 from non-inclusion of l(3)82Fc (FBrf0075380)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	5-HT2 (Colas et al., 1999, Colas et al., 1995, Megraw and Kaufman, 1998.10.2, Schaerlinger et al., 2007) atms (Megraw and Kaufman, 1998.10.2, Colas et al., 1999) bob (Megraw and Kaufman, 1998.10.2) cno (Megraw and Kaufman, 1998.10.2) corto (Megraw and Kaufman, 1998.10.2) fs(3)82CDa (Megraw and Kaufman, 1998.10.2) fs(3)82CDb (Megraw and Kaufman, 1998.10.2) fs(3)82EFa (Megraw and Kaufman, 1998.10.2) fs(3)82EFb (Megraw and Kaufman, 1998.10.2) fs(3)82EFc (Megraw and Kaufman, 1998.10.2) fs(3)82EFd (Megraw and Kaufman, 1998.10.2) fs(3)82EFe (Megraw and Kaufman, 1998.10.2) Gnf1 (Megraw and Kaufman, 1998.10.2) Karyβ3 (Megraw and Kaufman, 1998.10.2, Colas et al., 1999, Schaerlinger et al., 2007) l(3)82CDc (Schaerlinger et al., 2007, Megraw and Kaufman, 1998.10.2) l(3)82CDe (Megraw and Kaufman, 1998.10.2) l(3)82Da (Megraw and Kaufman, 1998.10.2) l(3)82Db (Megraw and Kaufman, 1998.10.2) l(3)82Ea (Megraw and Kaufman, 1998.10.2) l(3)82Eb (Megraw and Kaufman, 1998.10.2) l(3)82EFa (Megraw and Kaufman, 1998.10.2) l(3)82EFb (Megraw and Kaufman, 1998.10.2) l(3)82EFc (Megraw and Kaufman, 1998.10.2) l(3)82Fa (Megraw and Kaufman, 1998.10.2, Carpenter, 1999, Carpenter, 1994) l(3)82Fb (Carpenter, 1999, Carpenter, 1994) l(3)02733 (Megraw and Kaufman, 1998.10.2, Colas et al., 1999) l(3)10112 (Colas et al., 1999) l(3)j4D1 (Colas et al., 1999) opa (Megraw and Kaufman, 1998.10.2, Colas et al., 1995) Rpp30 (Colas et al., 1999) shk (Colas et al., 1999) tacc (Gergely et al., 2000)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	corto (Megraw and Kaufman, 1998.10.2) hd (Carpenter, 1999, Carpenter, 1994) Hph (Carpenter, 1999, Carpenter, 1994) kkv (Carpenter, 1999, Carpenter, 1994) l(3)82Fc (Carpenter, 1999, Carpenter, 1994) l(3)82Fg (Carpenter, 1999, Carpenter, 1994) l(3)82Fi (Carpenter, 1999, Carpenter, 1994) l(3)82Fj (Carpenter, 1999, Carpenter, 1994) l(3)00714 (Megraw and Kaufman, 1998.10.2) l(3)01107 (Megraw and Kaufman, 1998.10.2) l(3)10112 (Megraw and Kaufman, 1998.10.2) l(3)j4B9 (Megraw and Kaufman, 1998.10.2) l(3)j4D1 (Megraw and Kaufman, 1998.10.2) l(3)ry103 (Megraw and Kaufman, 1998.10.2) l(3)s2521 (Megraw and Kaufman, 1998.10.2) mtd (Carpenter, 1999, Carpenter, 1994) S(CycE^JP)68S10 (Brumby et al., 2004)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Heterozygotes with P{RS3}3 eclose at the same frequency and have the same phenotype as their P{RS3}3/balancer siblings. (Martin-Morris et al., 1997)
NOT in combination with other aberrations	The Df(3R)110 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion). (Mason et al., 2004) Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) Does not remove 82F puff. (Carpenter, 1994)
Stocks ( 2 )
Bloomington	1559 Df(3R)110, ru¹ th¹ st¹ kni^ri-1 rn^roe-1 p^p e^s ca¹/TM3, Sb¹
Kyoto	106386 Df(3R)110, ru¹ th¹ st¹ kni^ri-1 rn^roe-1 p^p e^s ca¹/TM3, Sb¹
Notes on Origin
Discoverer	S. Wasserman.
	ru th st ri roe p^p e^s ca (Wasserman, 1991.4)
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(3R)110 (Schaerlinger et al., 2007, Lee et al., 2007, Abdu et al., 2007, Lerit and Gavis, 2011)
Name Synonym
Secondary FlyBase IDs

References ( 20 )
Research paper	Lerit and Gavis, 2011, Curr. Biol. 21(6): 439--448 Transport of germ plasm on astral microtubules directs germ cell development in Drosophila. [FBrf0213255] Abdu et al., 2007, J. Cell Sci. 120(6): 1042--1049 An essential role for Drosophila hus1 in somatic and meiotic DNA damage responses. [FBrf0193459] Lee et al., 2007, Development 134(7): 1301--1310 The Zic family member, odd-paired, regulates the Drosophila BMP, decapentaplegic, during adult head development. [FBrf0192587] Schaerlinger et al., 2007, Dev. Dyn. 236(4): 991--999 Gain of affinity point mutation in the serotonin receptor gene 5-HT(2Dro) accelerates germband extension movements during Drosophila gastrulation. [FBrf0194099] Brumby et al., 2004, Genetics 168(1): 227--251 A genetic screen for dominant modifiers of a cyclin E hypomorphic mutation identifies novel regulators of S-phase entry in Drosophila. [FBrf0180291] Frei and Edgar, 2004, Dev. Cell 6(2): 241--251 Drosophila cyclin D/Cdk4 requires Hif-1 prolyl hydroxylase to drive cell growth. [FBrf0174538] Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Cullen and Ohkura, 2001, Nat. Cell Biol. 3(7): 637--642 Msps protein is localized to acentrosomal poles to ensure bipolarity of Drosophila meiotic spindles. [FBrf0137061] Gergely et al., 2000, EMBO J. 19(2): 241--252 D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo. [FBrf0123017] Carpenter, 1999, D. I. S. 82: 113--114 Saturation mutagenesis of region 82F. [FBrf0111824] Colas et al., 1999, Mech. Dev. 87(1-2): 77--91 Serotonin synchronises convergent extension of ectoderm with morphogenetic gastrulation movements in Drosophila. [FBrf0111346] Martin-Morris et al., 1997, Genetics 147(2): 671--677 Heterochromatic trans-inactivation of Drosophila white transgenes. [FBrf0098841] Colas et al., 1995, Proc. Natl. Acad. Sci. U.S.A. 92(12): 5441--5445 Drosophila 5-HT₂ serotonin receptor: coexpression with fushi-tarazu during segmentation. [FBrf0081644] Pauli et al., 1995, Genetics 139(2): 713--732 Identification of regions interacting with ovo^D mutations: Potential new genes involved in germline sex determination or differentiation in Drosophila melanogaster. [FBrf0080317] Pauli et al., 1995, D. I. S. 76: 107--124 Dose dependent enhancers and suppressors of ovoD2. [FBrf0082455] Benedyk et al., 1994, Genes Dev. 8(1): 105--117 odd-paired: a zinc finger pair-rule protein required for the timely activation of engrailed and wingless in Drosophila embryos. [FBrf0068410]
Personal communication to FlyBase	Megraw and Kaufman, 1998.10.2, Megraw 82CfMegraw complementation groups. Megraw 82CfMegraw complementation groups. [FBrf0104943] Wasserman, 1991.4, [title not yet available] [title not yet available] [FBrf0080715]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Stock list	Carpenter, 1994, Excerpt from stocklist II. Excerpt from stocklist II. [FBrf0075380]