Aberration Dmel\Df(3R)6-7

General Information
Symbol	Dmel\Df(3R)6-7	Species	D. melanogaster
Name		FlyBase ID	FBab0002478
Feature type	chromosomal_deletion

Computed Breakpoints include	82D5;82F3-82F6
Deleted segment	82D5--82F6
Sequence coordinates
Recent Updates
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FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	gamma ray (Wasserman, 1991.4)
Class of aberration (relative to progenitor)	chromosomal_deletion (Castrillon et al., 1993, Miyamoto et al., 1995, Pauli et al., 1995, Colas et al., 1995, Kodjabachian et al., 1998)
Breakpoints	82D3-82D8;82F (Colas et al., 1995) 82D3-82D8;82F3-82F6 (Castrillon et al., 1993, Miyamoto et al., 1995, Pauli et al., 1995) 82D-82E;82F (Kodjabachian et al., 1998)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data	atms << bk1 << bob << l(3)82Fc << bk2 << l(3)82Fj
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from non-inclusion of l(3)01456 (FBrf0104943) Right limit of break 1 from inclusion of l(3)02733 (FBrf0104943) Left limit of break 2 from inclusion of l(3)82Fc (FBrf0075380) Right limit of break 2 from polytene analysis (FBrf0064394)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	bob (Megraw and Kaufman, 1998.10.2, Castrillon et al., 1993) cno (Megraw and Kaufman, 1998.10.2, Miyamoto et al., 1995, Matsuo et al., 1997) corto (Megraw and Kaufman, 1998.10.2, Lopez et al., 2001) E(ftz)1815 (Kankel et al., 2004) fs(3)82EFa (Megraw and Kaufman, 1998.10.2) fs(3)82EFb (Megraw and Kaufman, 1998.10.2) fs(3)82EFc (Megraw and Kaufman, 1998.10.2) fs(3)82EFd (Megraw and Kaufman, 1998.10.2) fs(3)82EFe (Megraw and Kaufman, 1998.10.2) Gnf1 (Megraw and Kaufman, 1998.10.2) Hph (Szeged Stock Center, 1998-) l(3)82Da (Megraw and Kaufman, 1998.10.2) l(3)82Db (Megraw and Kaufman, 1998.10.2) l(3)82Ea (Megraw and Kaufman, 1998.10.2) l(3)82Eb (Megraw and Kaufman, 1998.10.2) l(3)82EFa (Megraw and Kaufman, 1998.10.2) l(3)82EFb (Megraw and Kaufman, 1998.10.2) l(3)82EFc (Megraw and Kaufman, 1998.10.2) l(3)82Fa (Megraw and Kaufman, 1998.10.2, Carpenter, 1999, Carpenter, 1994) l(3)82Fb (Carpenter, 1999, Carpenter, 1994) l(3)82Fc (Carpenter, 1999, Carpenter, 1994) l(3)82Fd (Carpenter, 1999, Carpenter, 1994) l(3)82Fe (Carpenter, 1999, Carpenter, 1994) l(3)02733 (Megraw and Kaufman, 1998.10.2) l(3)S024151 (Szeged Stock Center, 1998-) l(3)S047418 (Szeged Stock Center, 1998-) opa (Megraw and Kaufman, 1998.10.2)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	5-HT2 (Colas et al., 1995, Megraw and Kaufman, 1998.10.2, Schaerlinger et al., 2007) atms (Megraw and Kaufman, 1998.10.2) fs(3)82CDa (Megraw and Kaufman, 1998.10.2) fs(3)82CDb (Megraw and Kaufman, 1998.10.2) hd (Carpenter, 1999, Carpenter, 1994) ins (Green and Piergentili, 2000) Karyβ3 (Megraw and Kaufman, 1998.10.2, Schaerlinger et al., 2007) kkv (Carpenter, 1999, Carpenter, 1994) l(3)82CDc (Schaerlinger et al., 2007, Megraw and Kaufman, 1998.10.2) l(3)82CDe (Megraw and Kaufman, 1998.10.2) l(3)82Fg (Carpenter, 1999, Carpenter, 1994) l(3)82Fi (Carpenter, 1999, Carpenter, 1994) l(3)82Fj (Carpenter, 1999, Carpenter, 1994)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Heterozygosity for Df(3R)6-7 results in 4.5% X chromosome nondisjunction and 1.4% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females. (Harris et al., 2003) Homozygous embryos have normal gut morphology. (Merabet et al., 2002) Loss of cno activity in Ras85D^V12.sev pupae does not affect over production of photoreceptor R7 cells. (Matsuo et al., 1997) Heterozygosity for this deletion suppresses the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) Does remove 82F puff. (Carpenter, 1994)
Stocks ( 3 )
Bloomington	339 w¹¹¹⁸; Df(3R)6-7/TM3, Sb¹
Kyoto	105857 w¹¹¹⁸; Df(3R)6-7/TM3, Sb¹ 101918 w¹¹¹⁸ ; Df(3R)6-7 / TM3, Sb¹
Notes on Origin
Discoverer	S. Wasserman.
	selected by removal of a P-element in 82F (Wasserman, 1991.4)
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The Df(3R)6-7 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but the eye colour phenotype in the presence of Df(3R)6-7 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing. In addition, any suppression is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies. (Mason et al., 2004)
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	6-7 (Provost et al., 2006) Df82D3,8-82F3,6 (Green and Piergentili, 2000) Df(3R)6-7 (Schaerlinger et al., 2007, Lee et al., 2007, Salvaing et al., 2008) Df(3R) 6-7 (Fiehler and Wolff, 2008) Df(3R)6.7 (Kodjabachian et al., 1998)
Name Synonym
Secondary FlyBase IDs

References ( 32 )

Generate a list of	All references relating to this aberration ( 32 )

List References by type	Research paper ( 26 ) Personal communication to FlyBase ( 2 ) Abstract ( 1 ) FlyBase analysis ( 1 ) Stock list ( 1 ) Computer file ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2010 Show research papers ...